Diabetes Mellitus, Non-Insulin-Dependent | Age
Item
has type 2 diabetes and is at least 18 years of age and no older than 78 years of age
boolean
C0011860 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Gender | Pregnancy Unlikely
Item
is male or is a female who is unlikely to conceive children
boolean
C0079399 (UMLS CUI [1])
C0032961 (UMLS CUI [2,1])
C0750558 (UMLS CUI [2,2])
PPAR-gamma Agonist Dose Stable | Metformin Dose Stable | Sulfonylurea Dose Stable
Item
is on stable doses of a peroxisome proliferator-activated receptor gamma agonist and metformin or metformin and a sulfonylurea agent
boolean
C2917405 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0025598 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0038766 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0205360 (UMLS CUI [3,3])
Diabetes Mellitus, Insulin-Dependent
Item
has type 1 diabetes
boolean
C0011854 (UMLS CUI [1])
Dipeptidyl-Peptidase IV Inhibitors | GLP-1 analogues
Item
has taken a dipeptidyl peptidase (dpp-4) inhibitor or a glucagon-like peptide-1 (glp-1) analogue
boolean
C1827106 (UMLS CUI [1])
C4301632 (UMLS CUI [2])
Weight Reduction Program | Maintenance Phase Absent | Weight-Loss Agents
Item
is on a weight loss program that is not in the maintenance phase or has started a weight loss medication within 8 weeks of screening
boolean
C3179079 (UMLS CUI [1])
C0024501 (UMLS CUI [2,1])
C0205390 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
C0376606 (UMLS CUI [3])
Operative Surgical Procedures | Major surgery Planned
Item
has had surgery within 30 days of screening or has major surgery planned during the study
boolean
C0543467 (UMLS CUI [1])
C0679637 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
Adrenal Cortex Hormones | Requirement Probably Adrenal Cortex Hormones
Item
is on or is likely to require treatment with corticosteroids for more than 2 weeks
boolean
C0001617 (UMLS CUI [1])
C1514873 (UMLS CUI [2,1])
C0750492 (UMLS CUI [2,2])
C0001617 (UMLS CUI [2,3])
Liver disease | Hepatitis B | Hepatitis C | Liver Cirrhosis | Gall Bladder Disease
Item
has a history of active liver disease, including hepatitis b or c, cirrhosis, or gallbladder disease
boolean
C0023895 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019196 (UMLS CUI [3])
C0023890 (UMLS CUI [4])
C0016977 (UMLS CUI [5])
HIV Seropositivity
Item
is human immunodeficiency virus (hiv) positive
boolean
C0019699 (UMLS CUI [1])
Congestive heart failure | New or Worsening Symptom Coronary heart disease
Item
has congestive heart failure, or has had new or worsening symptoms of coronary heart disease within 3 months prior to screening
boolean
C0018802 (UMLS CUI [1])
C3898139 (UMLS CUI [2,1])
C0010068 (UMLS CUI [2,2])
Acute Coronary Syndrome | Coronary artery Intervention | Cerebrovascular accident
Item
has had acute coronary syndrome, coronary artery intervention, or stroke within 3 months of screening
boolean
C0948089 (UMLS CUI [1])
C0205042 (UMLS CUI [2,1])
C0184661 (UMLS CUI [2,2])
C0038454 (UMLS CUI [3])
Peripheral Vascular Disease Severe
Item
has severe active peripheral vascular disease
boolean
C0085096 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Malignant Neoplasms | Hematological Disease
Item
has a history of cancer or blood disorder
boolean
C0006826 (UMLS CUI [1])
C0018939 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
is pregnant or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])