Diabetes Mellitus, Non-Insulin-Dependent | Poor glycemic control | Hemoglobin A1c measurement
Item
subjects with type 2 diabetes and inadequate glycemic control, defined as a1c ≥ 7.0 and ≤ 10.0% at the enrollment visit
boolean
C0011860 (UMLS CUI [1])
C0342299 (UMLS CUI [2])
C0474680 (UMLS CUI [3])
Metformin | Pills Insulin Release
Item
subjects should have been receiving either metformin therapy or metformin therapy and one insulin secretagogue for at least 12 weeks prior to enrollment
boolean
C0025598 (UMLS CUI [1])
C0994475 (UMLS CUI [2,1])
C0021641 (UMLS CUI [2,2])
C1283071 (UMLS CUI [2,3])
C-peptide measurement
Item
c-peptide ≥ 1.0 ng/ml (0.34 nmol/l)
boolean
C0202100 (UMLS CUI [1])
Body mass index
Item
bmi ≤ 45.0 kg/m2
boolean
C1305855 (UMLS CUI [1])
Urine albumin/creatinine ratio measurement
Item
urine albumin to creatinine ratio (uacr) > 1,800 mg/g (203.4 mg/mmol/cr)
boolean
C0455271 (UMLS CUI [1])
Aspartate aminotransferase increased
Item
aspartate aminotransferase (ast) > 3x upper limit of normal (uln)
boolean
C0151904 (UMLS CUI [1])
Alanine aminotransferase increased
Item
alanine aminotransferase (alt) > 3x uln
boolean
C0151905 (UMLS CUI [1])
Serum total bilirubin measurement
Item
serum total bilirubin > 2 mg/dl (34.2 μmol/l)
boolean
C1278039 (UMLS CUI [1])
Creatinine measurement, serum | Gender
Item
serum creatinine (scr) ≥ 1.50 mg/dl (133 μmol/l) for men; scr ≥ 1.40 mg/dl (124
boolean
C0201976 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
ID.10
Item
μmol/l) for women
boolean
Cardiovascular Diseases Unstable | Kidney Diseases Unstable | Liver diseases Unstable | Hematological Disease Unstable | Malignant disease Unstable | Endocrine System Diseases Unstable | Mental disorders Unstable | Rheumatism Unstable | Cardiovascular Diseases Serious | Kidney Diseases Serious | Liver diseases Serious | Hematological Disease Serious | Malignant disease Serious | Endocrine System Diseases Serious | Mental disorders Serious | Rheumatism Serious
Item
currently unstable or serious cardiovascular, renal, hepatic, hematological, oncological, endocrine, psychiatric, or rheumatic diseases
boolean
C0007222 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0022658 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0023895 (UMLS CUI [3,1])
C0443343 (UMLS CUI [3,2])
C0018939 (UMLS CUI [4,1])
C0443343 (UMLS CUI [4,2])
C0442867 (UMLS CUI [5,1])
C0443343 (UMLS CUI [5,2])
C0014130 (UMLS CUI [6,1])
C0443343 (UMLS CUI [6,2])
C0004936 (UMLS CUI [7,1])
C0443343 (UMLS CUI [7,2])
C0035435 (UMLS CUI [8,1])
C0443343 (UMLS CUI [8,2])
C0007222 (UMLS CUI [9,1])
C0205404 (UMLS CUI [9,2])
C0022658 (UMLS CUI [10,1])
C0205404 (UMLS CUI [10,2])
C0023895 (UMLS CUI [11,1])
C0205404 (UMLS CUI [11,2])
C0018939 (UMLS CUI [12,1])
C0205404 (UMLS CUI [12,2])
C0442867 (UMLS CUI [13,1])
C0205404 (UMLS CUI [13,2])
C0014130 (UMLS CUI [14,1])
C0205404 (UMLS CUI [14,2])
C0004936 (UMLS CUI [15,1])
C0205404 (UMLS CUI [15,2])
C0035435 (UMLS CUI [16,1])
C0205404 (UMLS CUI [16,2])