Informed Consent
Item
written informed consent prior to any study activities
boolean
C0021430 (UMLS CUI [1])
Age
Item
age 18-75 years old
boolean
C0001779 (UMLS CUI [1])
Squamous cell carcinoma of mouth | Squamous cell carcinoma of tongue | Squamous cell carcinoma of gingiva | Squamous cell carcinoma of buccal mucosa | Squamous cell carcinoma of floor of mouth | Squamous cell carcinoma of palate | Squamous cell carcinoma Retromolar region
Item
histological biopsy confirming oral squamous cell carcinoma (tongue, gingiva, buccal mucosa, floor of mouth, palate, and retromolar region)
boolean
C0585362 (UMLS CUI [1])
C0349566 (UMLS CUI [2])
C0349567 (UMLS CUI [3])
C0280299 (UMLS CUI [4])
C0280300 (UMLS CUI [5])
C0349568 (UMLS CUI [6])
C0007137 (UMLS CUI [7,1])
C4247023 (UMLS CUI [7,2])
TNM clinical staging | Lesion Resectable
Item
clinical stage iii/iva (t1-2, n1-2, m0 or t3-4, n0-2, m0, uicc 2002), resectable lesions
boolean
C3258246 (UMLS CUI [1])
C0221198 (UMLS CUI [2,1])
C1514888 (UMLS CUI [2,2])
Karnofsky Performance Status
Item
karnofsky performance status (kps) > 60
boolean
C0206065 (UMLS CUI [1])
Hematologic function | White Blood Cell Count procedure | Hemoglobin measurement | Platelet Count measurement
Item
adequate hematologic function: white blood cell > 3,000/mm^3, hemoglobin > 8g/l, platelet count > 80,000/mm^3
boolean
C0221130 (UMLS CUI [1])
C0023508 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
Liver function | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Serum total bilirubin measurement
Item
hepatic function: alat/asat < 2.5 times the upper limit of normal (uln), bilirubin < 1.5 times uln
boolean
C0232741 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
Renal function | Creatinine measurement, serum
Item
renal function: serum creatinine < 1.5 x uln
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Life Expectancy
Item
life expectancy ≥ 6 months
boolean
C0023671 (UMLS CUI [1])
Distant metastasis | Cancer Other
Item
evidence of distant metastatic disease and other cancers
boolean
C1269798 (UMLS CUI [1])
C1707251 (UMLS CUI [2])
Operative Surgical Procedures Primary tumor | Operative Surgical Procedures Lymph nodes | Exception Biopsy
Item
surgical procedure of the primary tumor or lymph nodes (except diagnostic biopsy) before study treatment
boolean
C0543467 (UMLS CUI [1,1])
C0677930 (UMLS CUI [1,2])
C0543467 (UMLS CUI [2,1])
C0024204 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0005558 (UMLS CUI [3,2])
Prior radiation therapy Primary tumor | Prior radiation therapy Lymph nodes
Item
previous radiotherapy for the primary tumor or lymph nodes
boolean
C0279134 (UMLS CUI [1,1])
C0677930 (UMLS CUI [1,2])
C0279134 (UMLS CUI [2,1])
C0024204 (UMLS CUI [2,2])
Prior Chemotherapy Primary tumor | Prior Immunotherapy Primary tumor
Item
prior chemotherapy or immunotherapy for the primary tumor
boolean
C1514457 (UMLS CUI [1,1])
C0677930 (UMLS CUI [1,2])
C1514461 (UMLS CUI [2,1])
C0677930 (UMLS CUI [2,2])
Cancer Other
Item
other previous malignancy within 5 years
boolean
C1707251 (UMLS CUI [1])
Disease systematic | Lung diseases Severe | Heart Diseases Severe
Item
systematic diseases history of severe pulmonary or cardiac diseases
boolean
C0012634 (UMLS CUI [1,1])
C0220922 (UMLS CUI [1,2])
C0024115 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0018799 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
Creatinine clearance measurement
Item
creatinine clearance < 30 ml/min
boolean
C0373595 (UMLS CUI [1])
Legal capacity Lacking | Legal capacity Limited
Item
legal incapacity or limited legal capacity
boolean
C0683673 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
C0683673 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
Pregnancy | Serum pregnancy test (B-HCG) | Choriogonadotropin.beta subunit (pregnancy test) Urine | Breast Feeding
Item
pregnancy (confirmed by serum or urine β-hcg) or lactation period
boolean
C0032961 (UMLS CUI [1])
C0430060 (UMLS CUI [2])
C2964947 (UMLS CUI [3])
C0006147 (UMLS CUI [4])