Solid Neoplasm Unresponsive to Treatment | Malignant lymphoid neoplasm Unresponsive to Treatment
Item
solid tumors or lymphoid malignancies refractory to standard therapy
boolean
C0280100 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0746336 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
Measurable Disease
Item
measurable disease
boolean
C1513041 (UMLS CUI [1])
Toxicity Due to Adverse event | Toxicity Due to Prior Chemotherapy | Recovery CTCAE Grades
Item
recovery to grade < 1 toxicity due to prior adverse event or chemotherapy
boolean
C0600688 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0877248 (UMLS CUI [1,3])
C0600688 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C1514457 (UMLS CUI [2,3])
C2004454 (UMLS CUI [3,1])
C1516728 (UMLS CUI [3,2])
Chemotherapy Absent
Item
no chemotherapy within 4 weeks of entering study
boolean
C0392920 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Age
Item
age > 18 years
boolean
C0001779 (UMLS CUI [1])
Karnofsky Performance Status
Item
karnofsy >= 60%
boolean
C0206065 (UMLS CUI [1])
Life Expectancy
Item
life expectancy > 3 months
boolean
C0023671 (UMLS CUI [1])
Organ function | Bone Marrow function
Item
normal or adequate organ and marrow function
boolean
C0678852 (UMLS CUI [1])
C0005953 (UMLS CUI [2,1])
C0031843 (UMLS CUI [2,2])
Investigational New Drugs
Item
receiving other investigational agents
boolean
C0013230 (UMLS CUI [1])
Metastatic malignant neoplasm to brain
Item
brain metastases
boolean
C0220650 (UMLS CUI [1])
Illness Uncontrolled
Item
uncontrolled medical illness
boolean
C0221423 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
HIV Seropositivity | Antiretroviral therapy combination
Item
hiv+ receiving combination antiretroviral therapy
boolean
C0019699 (UMLS CUI [1])
C1963724 (UMLS CUI [2,1])
C2193864 (UMLS CUI [2,2])
Gastrointestinal Disease
Item
significant gi disease
boolean
C0017178 (UMLS CUI [1])