Informed Consent | Informed Consent Legal Guardian
Item
subjects who (or as appropriate whose legal guardian) have been informed of the study procedures and medications and have given their written informed consent
boolean
C0021430 (UMLS CUI [1])
C0021430 (UMLS CUI [2,1])
C0023226 (UMLS CUI [2,2])
Allergic asthma Severe | omalizumab | Treatment Requirement Fulfill
Item
subjects with severe allergic asthma that based on standard practice have been assigned to omalizumab treatment and fulfill all requirements for such treatment
boolean
C0155877 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0966225 (UMLS CUI [2])
C0087111 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
C1550543 (UMLS CUI [3,3])
Requirement Included
Item
the requirements include:
boolean
C1514873 (UMLS CUI [1,1])
C0332257 (UMLS CUI [1,2])
Severe asthma Uncontrolled | Therapy Optimal Maximal | Initiative Global Asthma Stage
Item
uncontrolled severe asthma despite maximal and optimal therapy , gina stage iv
boolean
C0581126 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C2698651 (UMLS CUI [2,2])
C0205289 (UMLS CUI [2,3])
C0424093 (UMLS CUI [3,1])
C2348867 (UMLS CUI [3,2])
C0004096 (UMLS CUI [3,3])
C1306673 (UMLS CUI [3,4])
Airway Obstruction Reversible | Change Percentage FEV1 Post bronchodilator
Item
reversible airway obstruction ( a change of 12% of fev1 after bronchodilator inhalation)
boolean
C0001883 (UMLS CUI [1,1])
C0205343 (UMLS CUI [1,2])
C0392747 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0849974 (UMLS CUI [2,3])
C2599594 (UMLS CUI [2,4])
Non-smoker | Tobacco use Smoking cigarettes: ____ pack-years history
Item
non smoking or smoking less then 10 py.
boolean
C0337672 (UMLS CUI [1])
C0543414 (UMLS CUI [2,1])
C2230126 (UMLS CUI [2,2])
Allergen skin test positive | RAST positive
Item
positive skin test or rast test for relevant allergen
boolean
C0855854 (UMLS CUI [1])
C0855586 (UMLS CUI [2])
Blood immunoglobulin E
Item
ige blood level between 30-700 iu and
boolean
C0853329 (UMLS CUI [1])
Exacerbation of asthma Quantity | Systemic steroids Required | Systemic steroids Continuing therapy
Item
two or more asthma exacerbation needed systemic steroids treatment during the last twelve months or continuing systemic steroid treatment. or
boolean
C0349790 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C2825233 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C2825233 (UMLS CUI [3,1])
C1553904 (UMLS CUI [3,2])
Medical contraindication Systemic steroids | Etiology Side effects | Osteoporosis | Diabetic - poor control
Item
contraindication to systemic steroid treatment due to side effects, such as osteoporosis and uncontrolled diabetes.
boolean
C1301624 (UMLS CUI [1,1])
C2825233 (UMLS CUI [1,2])
C0015127 (UMLS CUI [2,1])
C0879626 (UMLS CUI [2,2])
C0029456 (UMLS CUI [3])
C0421258 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
pregnancy or nursing mothers
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Severe allergy Xolair
Item
subject who have experienced a severe hypersensitivity reaction to xolair®
boolean
C2945656 (UMLS CUI [1,1])
C1174773 (UMLS CUI [1,2])