Schizophrenia
Item
patient meets the criteria for schizophrenia
boolean
C0036341 (UMLS CUI [1])
Antipsychotic Agents Oral Dose Adequate | Prior Therapy Unsuccessful | Lack of Efficacy | Intolerance to substance | Safety Lacking | Medication Compliance Lacking | Change Antipsychotic Agent Other
Item
patient is previously non-acute and has been given an adequate dose of an appropriate oral antipsychotic for an adequate period of time prior to enrollment, but previous treatment is considered unsuccessful due to one or more of the following reasons: lack of efficacy, lack of tolerability or safety, lack of compliance and/or other reasons to switch to another antipsychotic medication
boolean
C0040615 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,3])
C0205411 (UMLS CUI [1,4])
C1514463 (UMLS CUI [2,1])
C1272705 (UMLS CUI [2,2])
C0235828 (UMLS CUI [3])
C1744706 (UMLS CUI [4])
C0036043 (UMLS CUI [5,1])
C0332268 (UMLS CUI [5,2])
C3489773 (UMLS CUI [6,1])
C0332268 (UMLS CUI [6,2])
C0392747 (UMLS CUI [7,1])
C0040615 (UMLS CUI [7,2])
C0205394 (UMLS CUI [7,3])
Healthy Volunteer Physical Examination | Healthy Volunteer Vital signs
Item
patient is healthy on the basis of a physical examination and vital signs at screening
boolean
C1708335 (UMLS CUI [1,1])
C0031809 (UMLS CUI [1,2])
C1708335 (UMLS CUI [2,1])
C0518766 (UMLS CUI [2,2])
Postmenopausal state | Female Sterilization | Gender Sexual Abstinence | Gender Sexually active Contraceptive methods
Item
women must be postmenopausal for at least 1 year, surgically sterile, abstinent, or, if sexually active, agree to practice an effective method of birth control before entry and throughout the study
boolean
C0232970 (UMLS CUI [1])
C0015787 (UMLS CUI [2])
C0079399 (UMLS CUI [3,1])
C0036899 (UMLS CUI [3,2])
C0079399 (UMLS CUI [4,1])
C0241028 (UMLS CUI [4,2])
C0700589 (UMLS CUI [4,3])
Clozapine | Injection of depot antipsychotic agent | Risperidone Injection Active Long-term
Item
patients on clozapine, any conventional depot neuroleptic or risperidone long-acting injections during the last 3 months
boolean
C0009079 (UMLS CUI [1])
C2585377 (UMLS CUI [2])
C4084406 (UMLS CUI [3,1])
C0205177 (UMLS CUI [3,2])
C0443252 (UMLS CUI [3,3])
Medical condition Unstable Serious | Laboratory test result abnormal
Item
patients with serious unstable medical condition, including known clinically relevant laboratory abnormalities
boolean
C3843040 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0205404 (UMLS CUI [1,3])
C0438215 (UMLS CUI [2])
Tardive Dyskinesia | Symptoms Tardive Dyskinesia | Neuroleptic Malignant Syndrome | Symptoms Neuroleptic Malignant Syndrome
Item
patients with history or current symptoms of tardive dyskinesia and neuroleptic malignant syndrome
boolean
C0686347 (UMLS CUI [1])
C1457887 (UMLS CUI [2,1])
C0686347 (UMLS CUI [2,2])
C0027849 (UMLS CUI [3])
C1457887 (UMLS CUI [4,1])
C0027849 (UMLS CUI [4,2])
High risk of Adverse event | High risk of Violence | High risk of Self-harm
Item
patients judged to be at high risk for adverse events, violence, or self-harm
boolean
C0332167 (UMLS CUI [1,1])
C0877248 (UMLS CUI [1,2])
C0332167 (UMLS CUI [2,1])
C0042693 (UMLS CUI [2,2])
C0332167 (UMLS CUI [3,1])
C0424366 (UMLS CUI [3,2])
Hypersensitivity Paliperidone | Risperidone allergy
Item
patients with known hypersensitivity to paliperidone er or to risperidone
boolean
C0020517 (UMLS CUI [1,1])
C0753678 (UMLS CUI [1,2])
C0570837 (UMLS CUI [2])
Substance Dependence
Item
patients with a current use or known history (over the past 6 months) of substance dependence
boolean
C0038580 (UMLS CUI [1])