Schizophrenia
Item
patients diagnosed with schizophrenia
boolean
C0036341 (UMLS CUI [1])
PANSS
Item
patient with positive and negative syndrome scale (panss) score of 80 to 120 at screening
boolean
C4086747 (UMLS CUI [1])
Antipsychotic Agents Absent | Schizophrenia
Item
patients who have not taken any antipsychotics in the past, and those were newly diagnosed with schizophrenia who have not taken any antipsychotics for at least one month prior to screening
boolean
C0040615 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0036341 (UMLS CUI [2])
Patient Healthy Physical Examination | Patient Healthy Laboratory examination | Patient Healthy Vital signs
Item
patient healthy on the basis of a physical examination, laboratory examination, and vital signs
boolean
C0030705 (UMLS CUI [1,1])
C3898900 (UMLS CUI [1,2])
C0031809 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C3898900 (UMLS CUI [2,2])
C0260877 (UMLS CUI [2,3])
C0030705 (UMLS CUI [3,1])
C3898900 (UMLS CUI [3,2])
C0518766 (UMLS CUI [3,3])
Gender Pregnancy test negative | Gender Contraceptive methods
Item
women must have a negative pregnancy test, and agree to practice an effective method of birth control before entry and throughout the study
boolean
C0079399 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Medical condition Serious Unstable | Laboratory test result abnormal
Item
serious unstable medical condition, including known clinically relevant laboratory abnormalities
boolean
C3843040 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0443343 (UMLS CUI [1,3])
C0438215 (UMLS CUI [2])
High risk of Adverse event | High risk of Violence | High risk of Self-harm
Item
judged to be at high risk for adverse events, violence or self-harm
boolean
C0332167 (UMLS CUI [1,1])
C0877248 (UMLS CUI [1,2])
C0332167 (UMLS CUI [2,1])
C0042693 (UMLS CUI [2,2])
C0332167 (UMLS CUI [3,1])
C0424366 (UMLS CUI [3,2])
Lacking Able to swallow Investigational New Drugs
Item
inability to swallow the study medication whole with the aid of water (patients may not chew, divide, dissolve, or crush the study medication)
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0013230 (UMLS CUI [1,3])
Abnormal biochemistry finding
Item
biochemistry results that are out of the laboratory's normal reference range and are deemed to be clinically significant by the investigator
boolean
C0586680 (UMLS CUI [1])
Substance Dependence
Item
patients with a current use or known history (over the past 6 months) of substance dependence
boolean
C0038580 (UMLS CUI [1])
Urine drug screen positive
Item
positive urine drug examination
boolean
C0743300 (UMLS CUI [1])