Schizophrenia
Item
participants meeting diagnostic and statistical manual of mental disorders-iv (dsm-iv) diagnosis criteria of schizophrenia
boolean
C0036341 (UMLS CUI [1])
Risperdal Dose Correct | Zyprexa Dose Correct | Seroquel Dose Correct | Study Subject Poorly controlled | Change of medication Required | Etiology Effectiveness Unsatisfactory | Etiology Intolerance to substance | Etiology Safety Problem
Item
participant receiving full course of treatment (6-8 weeks) at correct dose (dose range recommended by the instruction) of risperdal, zyprexa or seroquel before enrollment, was poorly controlled and had to change medication because of unsatisfying efficacy, tolerability or safety issues, or other reason
boolean
C0592071 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C2349182 (UMLS CUI [1,3])
C0527258 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C2349182 (UMLS CUI [2,3])
C0287163 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C2349182 (UMLS CUI [3,3])
C0681850 (UMLS CUI [4,1])
C3853134 (UMLS CUI [4,2])
C0580105 (UMLS CUI [5,1])
C1514873 (UMLS CUI [5,2])
C0015127 (UMLS CUI [6,1])
C1280519 (UMLS CUI [6,2])
C0439856 (UMLS CUI [6,3])
C0015127 (UMLS CUI [7,1])
C1744706 (UMLS CUI [7,2])
C0015127 (UMLS CUI [8,1])
C0036043 (UMLS CUI [8,2])
C0033213 (UMLS CUI [8,3])
Antipsychotic Agents Quantity | Stable Disease Relative
Item
participant in the non-acute phase during screening received treatment with any of above three antipsychotics within 4 weeks before enrollment and state of illness was relatively stable
boolean
C0040615 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0677946 (UMLS CUI [2,1])
C0205345 (UMLS CUI [2,2])
Postmenopausal state | Female Sterilization | Gender Sexual Abstinence | Gender Sexually active Contraceptive methods | Hormonal contraception | Contraceptive injection | Intrauterine Devices | Barrier Contraception Double | Contraceptive patch | Partner had vasectomy | Gender Urine pregnancy test negative
Item
7. female participants must be postmenopausal for at least 1 year, surgically sterile, abstinent, or, if sexually active, agree to practice an effective method of birth control before entry and throughout the study. effective methods of birth control include prescription hormonal contraceptives, contraceptive injections, intrauterine devices, double barrier method, contraceptive patch and male partner sterilization. female participants must also have a negative urine pregnancy test at screening
boolean
C0232970 (UMLS CUI [1])
C0015787 (UMLS CUI [2])
C0079399 (UMLS CUI [3,1])
C0036899 (UMLS CUI [3,2])
C0079399 (UMLS CUI [4,1])
C0241028 (UMLS CUI [4,2])
C0700589 (UMLS CUI [4,3])
C2985296 (UMLS CUI [5])
C1656586 (UMLS CUI [6])
C0021900 (UMLS CUI [7])
C0004764 (UMLS CUI [8,1])
C0205173 (UMLS CUI [8,2])
C2985284 (UMLS CUI [9])
C0420842 (UMLS CUI [10])
C0079399 (UMLS CUI [11,1])
C0430057 (UMLS CUI [11,2])
Questionnaires Completion Self
Item
participant willing to and who could complete questionnaire by himself
boolean
C0034394 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C0036588 (UMLS CUI [1,3])
Clozapine Injection | Risperidone microspheres Injection
Item
participant receiving treatment with clozapine or risperidone microspheres for injection (hengde) within 3 months before screening
boolean
C0009079 (UMLS CUI [1,1])
C1828121 (UMLS CUI [1,2])
C1337134 (UMLS CUI [2,1])
C1828121 (UMLS CUI [2,2])
Seizure | Exception Febrile Convulsion
Item
participant having history of seizure except febrile convulsion (seizures that occur during a febrile episode [fever])
boolean
C0036572 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0009952 (UMLS CUI [2,2])
Refractory schizophrenia | Antipsychotic Agents Different Quantity | Treatment Effectiveness Unsatisfactory
Item
participant having refractory schizophrenia (previous treatment with unsatisfied efficacy of 2 or more than 2 kinds of antipsychotics with different chemical structure after adequate dose and duration)
boolean
C2063865 (UMLS CUI [1])
C0040615 (UMLS CUI [2,1])
C1705242 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0087111 (UMLS CUI [3,1])
C1280519 (UMLS CUI [3,2])
C0439856 (UMLS CUI [3,3])
Electroconvulsive Therapy
Item
participant receiving electric shock treatment within 1 month before screening
boolean
C0013806 (UMLS CUI [1])
Physical illness Serious Unstable
Item
participant having serious, unstable physical diseases
boolean
C0683323 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0443343 (UMLS CUI [1,3])