Adult | Age
Item
adult patients >/= 18 years of age
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Rheumatoid arthritis moderate Duration | Rheumatoid Arthritis Severe Duration | Methotrexate Response Inadequate | Anti-TNF drug Response Inadequate
Item
active moderate or severe rheumatoid arthritis of <10 years duration with inadequate response to methotrexate or anti-tnf
boolean
C2368567 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C0003873 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
C0025677 (UMLS CUI [3,1])
C1704632 (UMLS CUI [3,2])
C0205412 (UMLS CUI [3,3])
C1562242 (UMLS CUI [4,1])
C1704632 (UMLS CUI [4,2])
C0205412 (UMLS CUI [4,3])
Methotrexate Dose Stable
Item
on methotrexate treatment for at least 10 weeks, at least 8 weeks on stable dose
boolean
C0025677 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Adrenal Cortex Hormones Oral Dose Stable | NSAIDs Dose Stable
Item
patients receiving oral corticosteroids and/or nsaids should be at stable dose for 4 weeks
boolean
C0001617 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,3])
C0205360 (UMLS CUI [1,4])
C0003211 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
Autoimmune Disease Rheumatic | Exception Rheumatoid Arthritis | Rheumatoid arthritis with systemic involvement
Item
rheumatic autoimmune disease other than ra, or significant systemic involvement secondary to ra
boolean
C0004364 (UMLS CUI [1,1])
C0035435 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0003873 (UMLS CUI [2,2])
C0494896 (UMLS CUI [3])
Rheumatoid Arthritis Functional Status Class
Item
functional class iv by acr classification
boolean
C0003873 (UMLS CUI [1,1])
C0598463 (UMLS CUI [1,2])
C0456387 (UMLS CUI [1,3])
Inflammatory joint disease | Exception Rheumatoid Arthritis
Item
history of inflammatory joint disease other than ra
boolean
C0683381 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0003873 (UMLS CUI [2,2])
B-cell depletion therapy | abatacept | rituximab
Item
previous treatment with cell-depleting therapies, abatacept or rituximab
boolean
C1171324 (UMLS CUI [1])
C1619966 (UMLS CUI [2])
C0393022 (UMLS CUI [3])
Communicable Disease | Recurrent infection | Episode Major Communicable Disease | Hospitalization Required | Requirement Antibiotics Intravenous | Requirement Antibiotics Oral
Item
active current or history of recurrent infection, or any major episode of infection requiring hospitalization or treatment with iv antibiotics <4 weeks or oral antibiotics <2 weeks prior to screening
boolean
C0009450 (UMLS CUI [1])
C0239998 (UMLS CUI [2])
C0332189 (UMLS CUI [3,1])
C0205164 (UMLS CUI [3,2])
C0009450 (UMLS CUI [3,3])
C1708385 (UMLS CUI [4])
C1514873 (UMLS CUI [5,1])
C0003232 (UMLS CUI [5,2])
C1522726 (UMLS CUI [5,3])
C1514873 (UMLS CUI [6,1])
C0003232 (UMLS CUI [6,2])
C1527415 (UMLS CUI [6,3])