Age
Item
males and females ≥ 18 years old
boolean
C0001779 (UMLS CUI [1])
Contraceptive methods Quantity Willing
Item
must be willing to practice 2 adequate methods of contraception for the duration of the study
boolean
C0700589 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0600109 (UMLS CUI [1,3])
Rheumatoid Arthritis Functional Status Class Disease length
Item
rheumatoid arthritis present for at least 3 months; functional class i, ii, or iii as defined by acr criteria
boolean
C0003873 (UMLS CUI [1,1])
C0598463 (UMLS CUI [1,2])
C0456387 (UMLS CUI [1,3])
C0872146 (UMLS CUI [1,4])
Methotrexate U/week | Methotrexate Dose Stable
Item
treatment with methotrexate (7.5 to 25 mg per week) for at least the last 3 months, and currently receiving stable dose methotrexate for at least one month prior to the start of the study
boolean
C0025677 (UMLS CUI [1,1])
C0560588 (UMLS CUI [1,2])
C0025677 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
Informed Consent
Item
ability to provide written informed consent
boolean
C0021430 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
women who are pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Arthritis Other
Item
history of other current inflammatory arthritis
boolean
C0003864 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Opportunistic Infection
Item
history of opportunistic infection
boolean
C0029118 (UMLS CUI [1])
Recurrent infections | Communicable Disease
Item
history of recurrent infections or current infection 2 weeks prior to start of study
boolean
C0239998 (UMLS CUI [1])
C0009450 (UMLS CUI [2])
Medical Problem Uncontrolled
Item
presence of significant, uncontrolled medical problems
boolean
C1254481 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Antirheumatic Drugs, Disease-Modifying | Exception Methotrexate
Item
treatment with any disease-modifying anti-rheumatoid drugs other than methotrexate within 4 weeks prior to start of study
boolean
C0242708 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0025677 (UMLS CUI [2,2])
Chondroitin Sulfates | Glucosamine Sulfate | Minocycline | Matrix Metalloproteinase Inhibitors | H2 blockers | Proton Pump Inhibitors | Misoprostol
Item
use of chondroitin sulfate, glucosamine sulfate, minocycline, or matrix metalloproteinase inhibitors, h-2 blockers, proton pump inhibitors, or misoprostol within 4 weeks prior to study start
boolean
C0008466 (UMLS CUI [1])
C0017720 (UMLS CUI [2])
C0026187 (UMLS CUI [3])
C1513016 (UMLS CUI [4])
C0019593 (UMLS CUI [5])
C0358591 (UMLS CUI [6])
C0085174 (UMLS CUI [7])
Live vaccine
Item
receipt of live vaccine within 8 weeks prior to study start
boolean
C0042211 (UMLS CUI [1])
Rheumatoid Arthritis Functional Status Class
Item
rheumatoid arthritis, functional class iv as defined by acr criteria
boolean
C0003873 (UMLS CUI [1,1])
C0598463 (UMLS CUI [1,2])
C0456387 (UMLS CUI [1,3])