Nasopharynx carcinoma relapse or refractory disease, EBV-genome or -anitgens
Item
nasopharyngeal carcinoma in first or subsequent relapse or with primary refractory disease in whom the ebv-genome or antigens have been demonstrated in tissue biopsy samples
boolean
C2931822 (UMLS CUI [1,1])
C0277556 (UMLS CUI [1,2])
C2931822 (UMLS CUI [2,1])
C1514815 (UMLS CUI [2,2])
C0014644 (UMLS CUI [3,1])
C0017428 (UMLS CUI [3,2])
C0005558 (UMLS CUI [3,3])
C0014644 (UMLS CUI [4,1])
C0003320 (UMLS CUI [4,2])
C0005558 (UMLS CUI [4,3])
Age
Item
age 10 years or older
boolean
C0001779 (UMLS CUI [1])
Life Expectancy
Item
life expectancy of 8 weeks or more
boolean
C0023671 (UMLS CUI [1])
Karnofsky Performance Status
Item
karnofsky or lansky score of 50 or more
boolean
C0206065 (UMLS CUI [1])
Normal bilirubin
Item
normal bilirubin level (per institutional standard)
boolean
C0005437 (UMLS CUI [1])
AST and ALT upper limit of normal
Item
ast and alt 1.5 x or less upper limit of normal
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
Alkaline phosphatase upper limit of normal
Item
alk phos level less than 2.5 x upper limit of normal
boolean
C0002059 (UMLS CUI [1])
ANC
Item
anc greater than 1500 cells/ul
boolean
C0948762 (UMLS CUI [1])
Hemoglobin
Item
hgb 8.0 or greater
boolean
C0019046 (UMLS CUI [1])
Platelets
Item
platelets 100,000 cells/ul or more
boolean
C0005821 (UMLS CUI [1])
Creatinin upper limit of normal, GFR
Item
creatinine 2 x or less uln or gfr 50 ml/min/1.73 m2 or more
boolean
C0201976 (UMLS CUI [1])
C0017654 (UMLS CUI [2])
Female of child bearing age; Contraceptive methods
Item
women of child-bearing potential must take/use effective birth control while participating in the study.
boolean
C1960468 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Pregnancy
Item
due to the unknown effects of this therapy on a fetus, pregnant women will be excluded from this research.
boolean
C0032961 (UMLS CUI [1])
Prior allergic to study drugs or other drugs formulated with polysorbate 80
Item
prior allergic reaction to the study drugs used in this protocol or other drugs formulated with polysorbate 80.
boolean
C0020517 (UMLS CUI [1,1])
C2603343 (UMLS CUI [1,2])
C0013227 (UMLS CUI [1,3])
C0020517 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C0032601 (UMLS CUI [2,3])
HIV positive
Item
known hiv positive subjects since treatment may be significantly immunosuppressive
boolean
C0019699 (UMLS CUI [1])
Breast Feeding
Item
women who are breast-feeding
boolean
C0006147 (UMLS CUI [1])
Communicable Diseases, uncontrolled medical condition
Item
severe intercurrent infection or uncontrolled condition
boolean
C0009450 (UMLS CUI [1])
C0205318 (UMLS CUI [2,1])
C0012634 (UMLS CUI [2,2])
Ability complying safety monitoring requirements
Item
patients, who in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study
boolean
C0036043 (UMLS CUI [1,1])
C1516647 (UMLS CUI [1,2])
C1321605 (UMLS CUI [1,3])
C0439801 (UMLS CUI [1,4])