Multiple myeloma (stage ii-iii )/ progressed, plasma cell leukemia; pathology report
Item
stage ii-iii multiple myeloma or have progression after initial treatment of stage i disease (durie salmon staging). patients with plasma cell leukemia are also included. pathology reviewed and the diagnosis confirmed at stanford university medical center.
boolean
C0026764 (UMLS CUI [1,1])
C4528204 (UMLS CUI [1,2])
C0026764 (UMLS CUI [2,1])
C0242656 (UMLS CUI [2,2])
C0231290 (UMLS CUI [2,3])
C0087111 (UMLS CUI [2,4])
C0023484 (UMLS CUI [3])
C0807321 (UMLS CUI [4])
Age
Item
age > 18 years and <= 75 years.
boolean
C0001779 (UMLS CUI [1])
Karnofsky performance status
Item
karnofsky performance status > 70%.
boolean
C0206065 (UMLS CUI [1])
Carbon monoxide diffusing capacity
Item
corrected dlco > 60%
boolean
C1516251 (UMLS CUI [1])
Left ventricle ejection fraction
Item
left ventricle ejection fraction (lvef) > 50%.
boolean
C0428772 (UMLS CUI [1])
ALT, AST, total bilirubin (except hemolysis and gilbert's disease)
Item
alt and ast must be <= 2x normal. total bilirubin <= 2 mg/dl unless hemolysis or gilbert's disease.
boolean
C0201836 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201913 (UMLS CUI [3])
C0332300 (UMLS CUI [4,1])
C0019054 (UMLS CUI [4,2])
C0332300 (UMLS CUI [5,1])
C0017551 (UMLS CUI [5,2])
Creatinine clearance
Item
estimated creatinine clearance > 50 ml/min.
boolean
C0373595 (UMLS CUI [1])
Hla-identical donor/one antigen/allele mismatched in hla-a, b, c or drb1
Item
have a related or unrelated hla-identical donor or one antigen/allele mismatched in hla-a, b, c or drb1.
boolean
C0019721 (UMLS CUI [1,1])
C0205280 (UMLS CUI [1,2])
C0013018 (UMLS CUI [1,3])
C0019728 (UMLS CUI [2,1])
C1881865 (UMLS CUI [2,2])
C0019737 (UMLS CUI [3,1])
C1881865 (UMLS CUI [3,2])
C0019751 (UMLS CUI [4,1])
C1881865 (UMLS CUI [4,2])
C0122040 (UMLS CUI [5,1])
C1881865 (UMLS CUI [5,2])
Informed consent
Item
signed informed consent.
boolean
C0021430 (UMLS CUI [1])
Age
Item
age >=17.
boolean
C0001779 (UMLS CUI [1])
HIV seronegative
Item
hiv seronegative
boolean
C0019698 (UMLS CUI [1])
Informed consent
Item
donor must be capable of giving signed, informed consent
boolean
C0021430 (UMLS CUI [1])
No contraindication filgrastim
Item
no contraindication to the administration of g-csf
boolean
C1298908 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
C0210630 (UMLS CUI [1,3])
Willing to have a central venous catheter
Item
willing to have a central venous catheter placed for apheresis if peripheral veins are inadequate.
boolean
C0600109 (UMLS CUI [1,1])
C1145640 (UMLS CUI [1,2])
Prior allogeneic hematopoietic cell transplantation
Item
prior allogeneic hematopoietic cell transplantation.
boolean
C1705576 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
Uncontrolled active infection
Item
uncontrolled active infection.
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Uncontrolled congestive heart failure/angina
Item
uncontrolled congestive heart failure or angina.
boolean
C0018802 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0002962 (UMLS CUI [2])
Pregnancy/breast feeding patients
Item
pregnancy or nursing patients will be excluded from the study.
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
Hiv positive
Item
those who are hiv-positive will be excluded from the study due to high risk of lethal infection after hematopoietic cell transplantation.
boolean
C0019699 (UMLS CUI [1])
Serious medical/psychological illness
Item
serious medical or psychological illness.
boolean
C0205082 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2])
Pregnancy, lactating
Item
pregnant or lactating women are not eligible
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
Prior malignancies (except for non-melanoma skin cancers)
Item
prior malignancies within the last 5 years except for non-melanoma skin cancers
boolean
C0006826 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
C0332300 (UMLS CUI [1,3])
C0677898 (UMLS CUI [1,4])
C0699893 (UMLS CUI [1,5])