Histologically confirmed (nasopharyngeal) non-keratinizing (WHO criteria)
Item
patients with newly histologically confirmed non-keratinizing (according to world health organization (who) histologically type).
boolean
C1334926 (UMLS CUI [1,1])
C1518321 (UMLS CUI [1,2])
C1301142 (UMLS CUI [2])
Tumor stage (american joint commission on cancer)
Item
tumor staged as t3-4n1/n2-3 (according to the 7th american joint commission on cancer edition).
boolean
C0441915 (UMLS CUI [1])
No distant metastasis
Item
no evidence of distant metastasis (m0).
boolean
C1298908 (UMLS CUI [1,1])
C1302548 (UMLS CUI [1,2])
KPS
Item
satisfactory performance status: karnofsky scale (kps) > 70.
boolean
C0206065 (UMLS CUI [1])
Leukocyte, Hemoglobin, Platelet count
Item
adequate marrow: leucocyte count ≥4000/μl, hemoglobin ≥90g/l and platelet count ≥100000/μl.
boolean
C0023508 (UMLS CUI [1])
C0019046 (UMLS CUI [2])
C0005821 (UMLS CUI [3])
ALT, AST, alkaline phosphatase, bilirubin
Item
normal liver function test: alanine aminotransferase (alt)、aspartate aminotransferase (ast) <1.5×upper limit of normal (uln) concomitant with alkaline phosphatase (alp) ≤2.5×uln, and bilirubin ≤uln.
boolean
C0232741 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0201850 (UMLS CUI [4])
C1278039 (UMLS CUI [5])
Creatinin clearance
Item
adequate renal function: creatinine clearance ≥60 ml/min.
boolean
C0232804 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Information about investigation of study, written informed consent
Item
patients must be informed of the investigational nature of this study and give written informed consent.
boolean
C0021430 (UMLS CUI [1])
WHO type keratinizing/basaloid squamous cell carcinoma
Item
who type keratinizing squamous cell carcinoma or basaloid squamous cell carcinoma.
boolean
C0334247 (UMLS CUI [1,1])
C1301142 (UMLS CUI [1,2])
C1266005 (UMLS CUI [2,1])
C1301142 (UMLS CUI [2,2])
Age
Item
age ≥60 years or <18 years.
boolean
C0001779 (UMLS CUI [1])
Palliative treatment
Item
treatment with palliative intent.
boolean
C1285530 (UMLS CUI [1])
Prior malignancy except treated basal/squamous cell cancer, cervical cancer
Item
prior malignancy except adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer.
boolean
C0006826 (UMLS CUI [1])
C0332300 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C0332300 (UMLS CUI [3,1])
C0007137 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
C0332300 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])
Pregnancy or lactation
Item
pregnancy or lactation.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Prior radiotherapy except for non-melanomatous skin cancers
Item
history of previous radiotherapy (except for non-melanomatous skin cancers outside intended rt treatment volume).
boolean
C0332152 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
C0332300 (UMLS CUI [2,1])
C1522449 (UMLS CUI [2,2])
C1518408 (UMLS CUI [2,3])
C0007114 (UMLS CUI [2,4])
Prior chemotherapy/surgery to primary tumor/nodes (except diagnostic)
Item
prior chemotherapy or surgery (except diagnostic) to primary tumor or nodes.
boolean
C1514457 (UMLS CUI [1])
C0744961 (UMLS CUI [2,1])
C0677930 (UMLS CUI [2,2])
C0744961 (UMLS CUI [3,1])
C0024204 (UMLS CUI [3,2])
C0332300 (UMLS CUI [4,1])
C0430022 (UMLS CUI [4,2])
Severe intercurrent disease bringing risk/affectin compliance (unstable cardiac disease, renal disease, chronic hepatitis, diabetes, emotional disturbance)
Item
any severe intercurrent disease, which may bring unacceptable risk or affect the compliance of the trial, for example, unstable cardiac disease requiring treatment, renal disease, chronic hepatitis, diabetes with poor control (fasting plasma glucose >1.5×uln), and emotional disturbance.
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0392760 (UMLS CUI [1,3])
C0525058 (UMLS CUI [1,4])
C0009488 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C1883420 (UMLS CUI [2,3])
C0035647 (UMLS CUI [2,4])
C0443343 (UMLS CUI [3,1])
C0018799 (UMLS CUI [3,2])
C0815189 (UMLS CUI [3,3])
C0022658 (UMLS CUI [4])
C0019189 (UMLS CUI [5])
C0011847 (UMLS CUI [6,1])
C0583513 (UMLS CUI [6,2])
C0004936 (UMLS CUI [7])