Age
Item
age 18-75
boolean
C0001779 (UMLS CUI [1])
Pulmonary arterial hypertension WHO classification | Peripheral Vascular Resistance Wood units Quantity | Pulmonary Capillary Wedge Pressure
Item
world health organization (who) group i pah with prior documentation of peripheral vascular resistance (pvr) > 3 wu and wedge(pcw) 16 or less.
boolean
C2973725 (UMLS CUI [1,1])
C4267671 (UMLS CUI [1,2])
C1258192 (UMLS CUI [2,1])
C0439525 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0086879 (UMLS CUI [3])
WHO classification
Item
who functional class i-iii
boolean
C4267671 (UMLS CUI [1])
6-Minute Walk Test Meter Quantity
Item
6 minute walk distance 150-575 meters
boolean
C0430515 (UMLS CUI [1,1])
C0475209 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Childbearing Potential Pregnancy test negative | Childbearing Potential Contraceptive methods
Item
women of child bearing potential must have a negative pregnancy test and be using effective contraception
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Phosphodiesterase 5 inhibitor Dose Stable Pulmonary arterial hypertension | sildenafil | tadalafil
Item
receiving therapy with phosphodiesterase-5 inhibitor for pah (sildenafil or tadalafil) for at least 3 months and with stable dose for at least 30 days
boolean
C1318700 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C2973725 (UMLS CUI [1,4])
C0529793 (UMLS CUI [2])
C1176316 (UMLS CUI [3])
Endothelin receptor antagonist Dose Stable
Item
if already receiving therapy with endothelin receptor antagonists must have been on therapy for at least 3 months and on stable dose for at least 30 days
boolean
C1134681 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Captopril allergy | Intolerance to Captopril | Angiotensin-converting-enzyme inhibitor allergy | Intolerance to Angiotensin-Converting Enzyme Inhibitors
Item
allergy or intolerance to captopril or other angiotensin converting enzyme inhibitors
boolean
C0571940 (UMLS CUI [1])
C1744706 (UMLS CUI [2,1])
C0006938 (UMLS CUI [2,2])
C0571939 (UMLS CUI [3])
C1744706 (UMLS CUI [4,1])
C0003015 (UMLS CUI [4,2])
Systolic Pressure Systemic
Item
systemic systolic blood pressure less than 100 mm hg
boolean
C0871470 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
Prostaglandins | Iloprost | Treprostinil | Epoprostenol
Item
therapy with prostanoids (iloprost, treprostinil, epoprostenol) within preceding 3 months
boolean
C0033554 (UMLS CUI [1])
C0079594 (UMLS CUI [2])
C1145760 (UMLS CUI [3])
C0033567 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
pregnant or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Creatinine measurement, serum
Item
creatinine > 2.0 mg/dl
boolean
C0201976 (UMLS CUI [1])
Serum potassium measurement
Item
potassium > 5.0 meq/dl
boolean
C0302353 (UMLS CUI [1])
Informed Consent Unable
Item
unable to provide informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Percent Predicted Total Lung Capacity | Percentage of predicted vital capacity
Item
tlc or vc <60% predicted
boolean
C3828589 (UMLS CUI [1])
C2919340 (UMLS CUI [2])
Obstructive Sleep Apnea untreated
Item
untreated obstructive sleep apnea
boolean
C0520679 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Left ventricular ejection fraction
Item
lvef < 40%
boolean
C0428772 (UMLS CUI [1])
Hemoglobin measurement
Item
hb < 10 mg/dl
boolean
C0518015 (UMLS CUI [1])