Age
Item
between 18 and 75 years of age
boolean
C0001779 (UMLS CUI [1])
Pulmonary arterial hypertension WHO classification | Idiopathic pulmonary arterial hypertension | Familial pulmonary arterial hypertension | Pulmonary arterial hypertension associated with congenital systemic-to-pulmonary shunt | Pulmonary arterial hypertension associated with congenital systemic-to-pulmonary shunt Repaired | Pulmonary arterial hypertension Associated with Collagen-vascular disease | Pulmonary arterial hypertension associated with HIV infection | Pulmonary arterial hypertension Associated with Appetite Depressants | Pulmonary arterial hypertension Associated with Use of Toxin
Item
pah diagnosis defined by following who group i categories: idiopathic/familial, associated with unrepaired or repaired congenital systemic-to-pulmonary shunts (repaired >/= 5 years), associated with collagen vascular disease, associated with hiv, associated with appetite suppressant/toxin use
boolean
C2973725 (UMLS CUI [1,1])
C4267671 (UMLS CUI [1,2])
C3203102 (UMLS CUI [2])
C1701939 (UMLS CUI [3])
C3698160 (UMLS CUI [4])
C3698160 (UMLS CUI [5,1])
C0205340 (UMLS CUI [5,2])
C2973725 (UMLS CUI [6,1])
C0332281 (UMLS CUI [6,2])
C0262428 (UMLS CUI [6,3])
C3697673 (UMLS CUI [7])
C2973725 (UMLS CUI [8,1])
C0332281 (UMLS CUI [8,2])
C0003620 (UMLS CUI [8,3])
C2973725 (UMLS CUI [9,1])
C0332281 (UMLS CUI [9,2])
C1524063 (UMLS CUI [9,3])
C0040549 (UMLS CUI [9,4])
6-Minute Walk Test Meter Quantity
Item
baseline six-minute walk distance (6mwd) >/= 250 meters
boolean
C0430515 (UMLS CUI [1,1])
C0475209 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Ventavis Dose Stable
Item
currently receiving ventavis and be stable at current dose for 30 days prior to baseline
boolean
C1541936 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Background Therapy Dose Stable | Endothelin receptor antagonist Dose Stable | Phosphodiesterase 5 inhibitor Dose Stable
Item
if currently receiving other approved background therapy (i.e. endothelin receptor antagonist or phosphodiesterase-5-inhibitor or both) must be on stable dose for 30 days prior to baseline
boolean
C1706907 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,3])
C0205360 (UMLS CUI [1,4])
C1134681 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C1318700 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0205360 (UMLS CUI [3,3])
Testing Consistent with Pulmonary arterial hypertension | Catheterization of right heart | Echocardiography
Item
previous testing (e.g. right heart catheterization, echocardiography) consistent with diagnosis of pah
boolean
C0039593 (UMLS CUI [1,1])
C0332290 (UMLS CUI [1,2])
C2973725 (UMLS CUI [1,3])
C0189896 (UMLS CUI [2])
C0013516 (UMLS CUI [3])
Breast Feeding | Pregnancy
Item
nursing or pregnant
boolean
C0006147 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
Comorbidity Except Inclusion criteria | Hypertension, Portal | Thromboembolism chronic | Pulmonary Veno-Occlusive Disease | Atrial septostomy
Item
has acute concomitant disease (e.g. portal hypertension, chronic thromboembolic disease, pulmonary veno-occlusive disease, etc) other than those accepted as part of the inclusion criteria or has had atrial septostomy
boolean
C0009488 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C1512693 (UMLS CUI [1,3])
C0020541 (UMLS CUI [2])
C0040038 (UMLS CUI [3,1])
C0205191 (UMLS CUI [3,2])
C0034091 (UMLS CUI [4])
C0397233 (UMLS CUI [5])
Sleep Apnea Uncontrolled | Heart Disease Left sided Uncontrolled | Lung disease Parenchymal Uncontrolled
Item
history of uncontrolled sleep apnea, left-sided heart disease, or parenchymal lung disease
boolean
C0037315 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0018799 (UMLS CUI [2,1])
C0443246 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
C0024115 (UMLS CUI [3,1])
C4277702 (UMLS CUI [3,2])
C0205318 (UMLS CUI [3,3])
Investigational New Drugs
Item
use of investigational drug within 30 days of baseline
boolean
C0013230 (UMLS CUI [1])