Age
Item
age range: 18-75 years old
boolean
C0001779 (UMLS CUI [1])
Incurable, relapsed or metastatic nasopharyngeal carcinoma
Item
histological confirmed incurable relapsed or metastatic nasopharyngeal carcinoma
boolean
C2931822 (UMLS CUI [1,1])
C0175969 (UMLS CUI [1,2])
C2931822 (UMLS CUI [2,1])
C0277556 (UMLS CUI [2,2])
C2931822 (UMLS CUI [3,1])
C0027627 (UMLS CUI [3,2])
Pre-treatment with platinum-containing regimen
Item
prior exposure of at least one line of platinum-containing regimen
boolean
C1514463 (UMLS CUI [1,1])
C3536920 (UMLS CUI [1,2])
ECOG Status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Life expectancy
Item
life expectancy of more than 3 months
boolean
C0023671 (UMLS CUI [1])
ANC, Platelet count, Hemoglobin
Item
bone marrow function: anc≧1.5×10^9/l, plt≧100×10^9/l, hb≧80g/l
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
Bilirubin, ALT and AST
Item
liver function: total bilirubin, alt and ast <1.5×unl
boolean
C0201913 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
Creatinine, Creatinine clearance
Item
renal function: cr<1.5×unl, ccr≧50ml/min
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Neuropathy
Item
without > 1 grade of neuropathy
boolean
C0442874 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1298908 (UMLS CUI [1,3])
Curative intent
Item
with curable treatment option
boolean
C1276305 (UMLS CUI [1,1])
C0332149 (UMLS CUI [1,2])
CNS involvement
Item
with cns involvement
boolean
C0449389 (UMLS CUI [1])
Prior platinum exposure in radiochemotherapy or as neo-/adjuvant regimen
Item
prior platinum exposure only in neo-adjuvant/adjuvant setting or concurrently used with radiotherapy
boolean
C1514457 (UMLS CUI [1,1])
C3536920 (UMLS CUI [1,2])
C0600558 (UMLS CUI [1,3])
C1514457 (UMLS CUI [2,1])
C3536920 (UMLS CUI [2,2])
C1522673 (UMLS CUI [2,3])
C0521116 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
Chemotherapy lines
Item
treated with > 2 lines of palliative chemotherapy
boolean
C0392920 (UMLS CUI [1,1])
C1285530 (UMLS CUI [1,2])
Prior exposure of s-1 or oxaliplatin
Item
with prior exposure of s-1 or oxaliplatin
boolean
C1514457 (UMLS CUI [1,1])
C0069717 (UMLS CUI [1,2])
C1514457 (UMLS CUI [2,1])
C0879262 (UMLS CUI [2,2])
History of malignancies
Item
history of other malignancies except cured basal cell carcinoma of skin and carcinoma in-situ of uterine cervix
boolean
C0262926 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0332300 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C0332300 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
Active infection
Item
significant active infection
boolean
C0009450 (UMLS CUI [1,1])
C0205177 (UMLS CUI [1,2])
Pregnancy status
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])