histological diagnosis of nasopharyngeal carcinoma
Item
histologically proven nasopharyngeal carcinoma for primary treatment with radical intent
boolean
C2931822 (UMLS CUI [1,1])
C0449575 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0439807 (UMLS CUI [2,2])
Non-keratinizing or undifferentiated carcinoma
Item
non-keratinizing or undifferentiated type
boolean
C1334926 (UMLS CUI [1])
C2931822 (UMLS CUI [2,1])
C0205698 (UMLS CUI [2,2])
Clinical stage UICC
Item
clinical stage iii-ivb (uicc 7th edition)
boolean
C0441914 (UMLS CUI [1,1])
C0205210 (UMLS CUI [1,2])
Age
Item
age between 18-70
boolean
C0001779 (UMLS CUI [1])
Karnofsky performance status
Item
satisfactory performance status: karnofsky scale (kps) > 70.
boolean
C0206065 (UMLS CUI [1])
Hemoglobin, wbc, platelet count
Item
hemoglobin > 100g/l, wbc > 4.0x10*9/l, plt > 100x10*9/l
boolean
C0023508 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0518015 (UMLS CUI [3])
serum creatinine, creatinine clearance
Item
serum creatinine level < 1.6 mg/dl or creatinine clearance ≥ 60 ml/min.
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
ALT, AST, ALP, Bilirubin
Item
normal liver function test: alanine aminotransferase (alt)、aspartate aminotransferase (ast) <1.5×upper limit of normal (uln) concomitant with alkaline phosphatase (alp)≤2.5×uln, and bilirubin ≤1.5uln
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201850 (UMLS CUI [3])
C0201913 (UMLS CUI [4])
Informed consent
Item
patients must be informed of the investigational nature of this study and give written informed consent.
boolean
C0021430 (UMLS CUI [1])
Life expectancy
Item
anticipated life span more than 6 month
boolean
C0023671 (UMLS CUI [1])
Palliative intent
Item
primary treatment with palliative intent
boolean
C1285530 (UMLS CUI [1])
Keratinizing or basaloid squamous cell carcinoma
Item
who type keratinizing squamous cell carcinoma or basaloid squamous cell carcinoma
boolean
C1301142 (UMLS CUI [1,1])
C0334247 (UMLS CUI [1,2])
C1266005 (UMLS CUI [1,3])
C1301142 (UMLS CUI [2,1])
C1266005 (UMLS CUI [2,2])
C1266005 (UMLS CUI [2,3])
Status of distant metastases
Item
Evidence of distant metastases
boolean
C1302548 (UMLS CUI [1])
Pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Previous radiotherapy
Item
history of previous radiotherapy (except for non-melanomatous skin cancers outside intended rt treatment volume).
boolean
C1522449 (UMLS CUI [1,1])
C2114510 (UMLS CUI [1,2])
C0332300 (UMLS CUI [2,1])
C0007114 (UMLS CUI [2,2])
C1518408 (UMLS CUI [2,3])
C1522449 (UMLS CUI [2,4])
Prior chemotherapy or surgery
Item
prior chemotherapy or surgery (except diagnostic) to primary tumor or nodes
boolean
C1514457 (UMLS CUI [1])
C0262926 (UMLS CUI [2,1])
C0597029 (UMLS CUI [2,2])
Prior malignancies
Item
prior malignancy except adequately treated basal cell or squamous cell skin cancer, in-situ cervical cancer or other cancer for which the patient has been disease-free for 5 years
boolean
C0006826 (UMLS CUI [1,1])
C0332132 (UMLS CUI [1,2])
C0332300 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C0332154 (UMLS CUI [2,3])
C0332300 (UMLS CUI [3,1])
C0007137 (UMLS CUI [3,2])
C0332154 (UMLS CUI [3,3])
C0332300 (UMLS CUI [4,1])
C0278587 (UMLS CUI [4,2])
C0332300 (UMLS CUI [5,1])
C0006826 (UMLS CUI [5,2])
C0242793 (UMLS CUI [5,3])
C3843495 (UMLS CUI [5,4])
Comorbidity or other medical contraindication
Item
any severe intercurrent disease, which may bring unacceptable risk or affect the compliance of the trial, for example, unstable cardiac disease requiring treatment, renal disease, chronic hepatitis, diabetes with poor control (fasting plasma glucose >1.5×uln), and emotional disturbance.
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0018799 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C0019189 (UMLS CUI [4])
C0421258 (UMLS CUI [5])
C0013985 (UMLS CUI [6])