Histological Diagnosis of nasopharyngeal carcinoma
Item
histologic diagnosis of nasopharyngeal carcinoma
boolean
C2931822 (UMLS CUI [1,1])
C0679557 (UMLS CUI [1,2])
Age group
Item
range from 18～69 years old
boolean
C0001779 (UMLS CUI [1])
TNM Stage
Item
t3-4，n0-2，m0 (ajcc 2009)
boolean
C0441915 (UMLS CUI [1])
KPS Score
Item
kps ≥ 80
boolean
C0206065 (UMLS CUI [1])
Nonmetastatic diseases
Item
nonmetastatic diseases
boolean
C0445092 (UMLS CUI [1])
WBC, hemoglobin and platelet count
Item
wbc count ≥ 4×10^9/l，hemoglobin ≥ 100g/l， platelet count ≥ 100×10^9/l
boolean
C0023508 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
Alt, ast and bilirubin
Item
alt or ast ＜ 1.5×uln, bilirubin ＜ 1.5×uln
boolean
C0201836 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
Creatinine
Item
serum creatinine ＜ 1.5×uln
boolean
C0201976 (UMLS CUI [1])
Distant metastases
Item
distan metastases
boolean
C1302548 (UMLS CUI [1])
Cancer previously treated with chemotherapy, surgery, immunotherapy, radiotherapy and/or egfr targeted therapy
Item
previously treated (surgery，chemotherapy, radiation therapy，egfr targeted therapy or immunotherapy)
boolean
C2114510 (UMLS CUI [1,1])
C0543467 (UMLS CUI [1,2])
C1514457 (UMLS CUI [2])
C1514461 (UMLS CUI [3])
C2114510 (UMLS CUI [4,1])
C1522449 (UMLS CUI [4,2])
C2114510 (UMLS CUI [5,1])
C1739039 (UMLS CUI [5,2])
C2985566 (UMLS CUI [5,3])
Previous malignancy
Item
second malignancy within 5 years
boolean
C0262926 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
Previous therapy with investigational agent
Item
previous therapy with an investigational agent
boolean
C2114510 (UMLS CUI [1,1])
C1521826 (UMLS CUI [1,2])
Uncontrolled seizure or serious neurologic disease
Item
uncontrolled seizure disorder or other serious neurologic disease
boolean
C0036572 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0027765 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Allergy to drugs in the study
Item
≥ grade ш allergic reaction to any drug including in this study
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
Cardiac or respiratory comorbidity
Item
clinically significant cardiac or respiratory disease
boolean
C0018799 (UMLS CUI [1])
C0024115 (UMLS CUI [2])
Creatinine clearance
Item
creatinine clearance < 30ml/min
boolean
C0373595 (UMLS CUI [1])
Substance abuse
Item
drug or alcohol addition
boolean
C0038586 (UMLS CUI [1])
Capacity for civil acts
Item
do not have full capacity for civil acts
boolean
C0683673 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
Active infection or severe complication
Item
severe complication, active infection
boolean
C0009450 (UMLS CUI [1])
C3495031 (UMLS CUI [2])
Concomitant immunotherapy or hormone therapy
Item
concurrent immunotherapy or hormone therapy for other diseases
boolean
C2347852 (UMLS CUI [1,1])
C0021083 (UMLS CUI [1,2])
C2347852 (UMLS CUI [2,1])
C0279025 (UMLS CUI [2,2])
Pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])