Age Groups All
Item
all age groups (amendment dated 1 june 2013)
boolean
C0027362 (UMLS CUI [1,1])
C0444868 (UMLS CUI [1,2])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Pulmonary Hypertension
Item
pulmonary hypertension (ph) of either
boolean
C0020542 (UMLS CUI [1])
Pulmonary arterial hypertension | Idiopathic pulmonary arterial hypertension
Item
pah: idiopathic form (ipah) or
boolean
C2973725 (UMLS CUI [1])
C3203102 (UMLS CUI [2])
Pulmonary arterial hypertension associated with connective tissue disease | Pulmonary arterial hypertension associated with congenital heart disease | Pulmonary arterial hypertension associated with HIV infection | Portopulmonary hypertension
Item
pah associated with connective tissue diseases (pah-ctd), with congenital heart defects (pah-chd), with hiv infection (pah-hiv), or the portopulmonary form
boolean
C3697982 (UMLS CUI [1])
C3697119 (UMLS CUI [2])
C3697673 (UMLS CUI [3])
C1868851 (UMLS CUI [4])
Chronic thromboembolic pulmonary hypertension
Item
chronic thromboembolic ph (cteph)
boolean
C2363973 (UMLS CUI [1])
Pulmonary hypertension due to left heart disease | Pulmonary hypertension due to left heart disease Associated with Isolated Diastolic dysfunction | Pulmonary hypertension due to left heart disease Associated with Systolic dysfunction
Item
ph in left heart diseases (with isolated diastolic dysfunction; with systolic dysfunction, other)
boolean
C3532326 (UMLS CUI [1])
C3532326 (UMLS CUI [2,1])
C0332281 (UMLS CUI [2,2])
C0520863 (UMLS CUI [2,3])
C0205409 (UMLS CUI [2,4])
C3532326 (UMLS CUI [3,1])
C0332281 (UMLS CUI [3,2])
C0749225 (UMLS CUI [3,3])
Pulmonary Hypertension Due to Lung disease | Pulmonary hypertension due to chronic obstructive pulmonary disease | Pulmonary Hypertension Due to Interstitial fibrosis
Item
ph in pulmonary disease (chronic obstructive pulmonary disease; interstitial fibrosis, etc.)
boolean
C0020542 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0024115 (UMLS CUI [1,3])
C3696884 (UMLS CUI [2])
C0020542 (UMLS CUI [3,1])
C0678226 (UMLS CUI [3,2])
C3887486 (UMLS CUI [3,3])
Pulmonary Hypertension Due to Congenital heart disease | Status post Cavopulmonary anastomosis | Status post Fontan type operation |
Item
"relative ph" in chd after cavopulmonary anastomosis or fontan-type surgery, even without the classical pulmonary pressure criteria of ph.
boolean
C0020542 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0152021 (UMLS CUI [1,3])
C0231290 (UMLS CUI [2,1])
C0242838 (UMLS CUI [2,2])
C0231290 (UMLS CUI [3,1])
C0190010 (UMLS CUI [3,2])
Therapeutic procedure Initiation | Endothelin receptor antagonist | Phosphodiesterase 5 inhibitor | Prostacyclin | Combined Modality Therapy
Item
newly initiated (i.e. a maximum of 3 months before documentation for the first time) therapy with era, pde-5 inhibitors or prostacyclins in mono- or combination therapy.
boolean
C0087111 (UMLS CUI [1,1])
C1704686 (UMLS CUI [1,2])
C1134681 (UMLS CUI [2])
C1318700 (UMLS CUI [3])
C0033567 (UMLS CUI [4])
C0009429 (UMLS CUI [5])
Exception | Maintenance therapy Including Pulmonary arterial hypertension associated with congenital heart disease | Therapeutic procedure Initiation Including Pulmonary arterial hypertension associated with congenital heart disease
Item
exceptions: pah-chd patients can be included on maintenance or newly initiated pah therapy (3-month rule dose not apply).
boolean
C1705847 (UMLS CUI [1])
C0677908 (UMLS CUI [2,1])
C0332257 (UMLS CUI [2,2])
C3697119 (UMLS CUI [2,3])
C0087111 (UMLS CUI [3,1])
C1704686 (UMLS CUI [3,2])
C0332257 (UMLS CUI [3,3])
C3697119 (UMLS CUI [3,4])
Pulmonary arterial hypertension with congenital heart disease Associated with Vascular disease of lung Severe | Eisenmenger Complex
Item
pah-chd patients with severe pulmonary vascular disease (e.g. eisenmenger physiology) irrespective of treatment with any pah drugs are eligible for inclusion, too.
boolean
C3697119 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C0543826 (UMLS CUI [1,3])
C0205082 (UMLS CUI [1,4])
C0013743 (UMLS CUI [2])
Maintenance therapy | Prior Therapy Endothelin receptor antagonist
Item
patients on maintenance therapy, i.e. previous treatment with any era/
boolean
C0677908 (UMLS CUI [1])
C1514463 (UMLS CUI [2,1])
C1134681 (UMLS CUI [2,2])
Phosphodiesterase 5 inhibitor | prostacyclin | soluble guanylyl cyclase | Exception Pulmonary arterial hypertension associated with congenital heart disease
Item
pde-v-inhibitor/prostacyclin/sgc stimulator drug longer than 3 months before documentation for the first time (exception: pah-chd patients).
boolean
C1318700 (UMLS CUI [1])
C0033567 (UMLS CUI [2])
C1097411 (UMLS CUI [3])
C1705847 (UMLS CUI [4,1])
C3697119 (UMLS CUI [4,2])