Adenocarcinoma of prostate
Item
histologically or cytologically confirmed adenocarcinoma of the prostate.
boolean
C0007112 (UMLS CUI [1])
Castration-resistant prostate cancer metastatic progressive | Status post Docetaxel Chemotherapy failed | Resistant to Docetaxel Chemotherapy | Intolerance to Docetaxel
Item
progressive, metastatic castration-resistant prostate cancer after failure of docetaxel chemotherapy (resistant or intolerant).
boolean
C1328504 (UMLS CUI [1,1])
C1522484 (UMLS CUI [1,2])
C0205329 (UMLS CUI [1,3])
C0231290 (UMLS CUI [2,1])
C0246415 (UMLS CUI [2,2])
C0392920 (UMLS CUI [2,3])
C0231175 (UMLS CUI [2,4])
C0332325 (UMLS CUI [3,1])
C0246415 (UMLS CUI [3,2])
C0392920 (UMLS CUI [3,3])
C1744706 (UMLS CUI [4,1])
C0246415 (UMLS CUI [4,2])
Progressive Disease PSA Progression | Progressive Disease Bone scan Positive
Item
progressive disease based on psa progression, recist, or positive bone scan.
boolean
C1335499 (UMLS CUI [1,1])
C4054264 (UMLS CUI [1,2])
C1335499 (UMLS CUI [2,1])
C0203668 (UMLS CUI [2,2])
C1514241 (UMLS CUI [2,3])
ECOG performance status
Item
ecog 0 or 1.
boolean
C1520224 (UMLS CUI [1])
Sunitinib | Chemotherapy Regimen Quantity Neoplasm Metastasis
Item
prior treatment with sunitinib and/or more than 1 prior chemotherapy regimen in the metastatic disease setting.
boolean
C1176020 (UMLS CUI [1])
C0392920 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0027627 (UMLS CUI [2,3])
Chemotherapy
Item
chemotherapy within 3 weeks.
boolean
C0392920 (UMLS CUI [1])
Complications Impending Due to Secondary malignant neoplasm of bone
Item
impending complications from bone metastases.
boolean
C0009566 (UMLS CUI [1,1])
C0332190 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C0153690 (UMLS CUI [1,4])
Urinary tract obstruction
Item
ongoing urinary obstruction.
boolean
C0178879 (UMLS CUI [1])
Cardiac dysfunction | Prolonged QTc
Item
cardiac dysfunction, qtc >470 msec.
boolean
C3277906 (UMLS CUI [1])
C1969409 (UMLS CUI [2])
Central Nervous System Involvement
Item
cns involvement.
boolean
C4050309 (UMLS CUI [1])