Primary central nervous system lymphoma
Item
first diagnosis of pcnsl, histologically confirmed
boolean
C0280803 (UMLS CUI [1])
Age
Item
age > 65 years
boolean
C0001779 (UMLS CUI [1])
Informed Consent Patient Representative | Informed Consent
Item
written signed and dated informed consent of the legal representative and - if possible - of the patient
boolean
C0021430 (UMLS CUI [1,1])
C0030701 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2])
Manifestation of Lymphoma Additional | Exception Central Nervous System
Item
manifestations of further lymphoma outside the cns
boolean
C1280464 (UMLS CUI [1,1])
C0024299 (UMLS CUI [1,2])
C1524062 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C3714787 (UMLS CUI [2,2])
HIV Seropositivity
Item
sero-positive for hiv
boolean
C0019699 (UMLS CUI [1])
Pulmonary function impairment Severe | Impairment cardiac Severe | Hepatic impairment Severe | Renal Insufficiency Severe
Item
severe pulmonary, cardiac, hepatic, renal impairment
boolean
C0858943 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0221099 (UMLS CUI [2,1])
C0018787 (UMLS CUI [2,2])
C0205082 (UMLS CUI [2,3])
C0948807 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C1565489 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
Communicable Disease Uncontrolled
Item
uncontrolled infection
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Neutrophil count | Platelet Count measurement
Item
neutrophil count < 1.500/µl, platelet count < 100.000/µl
boolean
C0200633 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
Lung disease | Inspiratory Vital Capacity Test | DLCO
Item
pulmonary disease with ivc < 55%, dlco < 40%
boolean
C0024115 (UMLS CUI [1])
C4085887 (UMLS CUI [2])
C1516251 (UMLS CUI [3])
Cardiac ejection fraction | Cardiac Arrhythmia Malignant Uncontrolled
Item
cardiac ejection fraction < 50%, uncontrolled malign arrhythmia
boolean
C0232174 (UMLS CUI [1])
C0003811 (UMLS CUI [2,1])
C0205282 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
Creatinine measurement, serum | Creatinine clearance measurement
Item
creatinine > 1,5 mg% or creatinine-clearance < 50ml/min
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Serum total bilirubin measurement
Item
bilirubin > 2mg/dl
boolean
C1278039 (UMLS CUI [1])
Ascites | Pleural effusion
Item
ascites or pleural effusion (> 500ml)
boolean
C0003962 (UMLS CUI [1])
C0032227 (UMLS CUI [2])
Methotrexate allergy | Lomustine allergy | Procarbazine allergy | Hypersensitivity Rituximab | Hypersensitivity Leucovorin | Dexamethasone allergy
Item
known hypersensitivity against methotrexate, lomustine, procarbazine, rituximab, leukovorin, or dexamethasone
boolean
C0570693 (UMLS CUI [1])
C0570678 (UMLS CUI [2])
C0570704 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0393022 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0023413 (UMLS CUI [5,2])
C0571611 (UMLS CUI [6])
Study Subject Participation Status
Item
participation in another clinical trial within the last 30 days prior to the begin or parallel to this study
boolean
C2348568 (UMLS CUI [1])
Substance Use Disorders
Item
known or current drug or alcohol abuse
boolean
C0038586 (UMLS CUI [1])