Blood pressure determination | Antihypertensive therapy
Item
bp≥140/90 mmhg in both of the two screening visits or currently under anti-hypertension treatment
boolean
C0005824 (UMLS CUI [1])
C0585941 (UMLS CUI [2])
Age
Item
45 - 75 years old
boolean
C0001779 (UMLS CUI [1])
MTHFR c677t Genotype determination
Item
successful determination of mthfr c677t genotype
boolean
C0943672 (UMLS CUI [1,1])
C1285573 (UMLS CUI [1,2])
Premenopausal state Contraceptive methods
Item
for pre-menopausal women, agreed to use contraceptives during the trial
boolean
C0232969 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Informed Consent
Item
signed the written informed consent
boolean
C0021430 (UMLS CUI [1])
Cerebrovascular accident
Item
having a history of stroke
boolean
C0038454 (UMLS CUI [1])
Myocardial Infarction
Item
having a history of myocardial infarction
boolean
C0027051 (UMLS CUI [1])
Heart failure
Item
having a history of physician diagnosed heart failure
boolean
C0018801 (UMLS CUI [1])
Status post Coronary revascularisation
Item
post- coronary revascularization
boolean
C0231290 (UMLS CUI [1,1])
C0877341 (UMLS CUI [1,2])
Disease Somatic Severe | Malignant Neoplasms
Item
severe somatic disease such as cancer
boolean
C0012634 (UMLS CUI [1,1])
C2986476 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C0006826 (UMLS CUI [2])
Secondary hypertension
Item
secondary hypertension
boolean
C0155616 (UMLS CUI [1])
Organic heart disease Congenital | Organic heart disease Acquired
Item
congenital or acquired organic heart diseases
boolean
C0747057 (UMLS CUI [1,1])
C1744681 (UMLS CUI [1,2])
C0747057 (UMLS CUI [2,1])
C0439661 (UMLS CUI [2,2])
Medical contraindication Angiotensin-Converting Enzyme Inhibitors
Item
contraindicated to angiotensin-converting enzyme inhibitor(acei)
boolean
C1301624 (UMLS CUI [1,1])
C0003015 (UMLS CUI [1,2])
Adverse effects ACEI
Item
history of acei adverse effects
boolean
C0879626 (UMLS CUI [1,1])
C0003015 (UMLS CUI [1,2])
Folic Acid Long-term | Vitamin B 12 Long-term | Vitamin B6 Long-term
Item
currently long-term use of folic acid or vitamin b12 or vitamin b6
boolean
C0016410 (UMLS CUI [1,1])
C0443252 (UMLS CUI [1,2])
C0042845 (UMLS CUI [2,1])
C0443252 (UMLS CUI [2,2])
C0087162 (UMLS CUI [3,1])
C0443252 (UMLS CUI [3,2])
Pregnancy | Breast Feeding
Item
pregnant or child breastfeeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Mental Disorders, Severe
Item
severe mental disorders
boolean
C4046029 (UMLS CUI [1])
Liver Dysfunction Laboratory Procedures | Abnormal renal function Laboratory Procedures
Item
lab tests indicating abnormal liver or kidney function
boolean
C0086565 (UMLS CUI [1,1])
C0022885 (UMLS CUI [1,2])
C0151746 (UMLS CUI [2,1])
C0022885 (UMLS CUI [2,2])
Study Subject Participation Status Unwilling | Antihypertensive therapy Change Unwilling
Item
unwilling to participate the trial, unwilling to change the current antihypertensive treatment
boolean
C2348568 (UMLS CUI [1,1])
C0558080 (UMLS CUI [1,2])
C0585941 (UMLS CUI [2,1])
C0392747 (UMLS CUI [2,2])
C0558080 (UMLS CUI [2,3])