Gender | Age
Item
female between the ages of 19 to 40 years of age
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Birth Recently
Item
given birth in the last 6 months
boolean
C0005615 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Breast Feeding Absent
Item
not currently breastfeeding
boolean
C0006147 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Major Depressive Disorder
Item
meet criteria for major depressive disorder as per the diagnostic and statistical manual of mental disorders, 4th edition (dsm-iv tr)
boolean
C1269683 (UMLS CUI [1])
Montgomery-Asberg Depression Rating Scale Questionnaire
Item
montgomery-asberg depression rating scale (madrs) score greater than or equal to 25 at enrolment
boolean
C4054475 (UMLS CUI [1])
Able to read English Language | Able to write English Language
Item
able to read and write english
boolean
C0586740 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0584993 (UMLS CUI [2,1])
C0376245 (UMLS CUI [2,2])
Informed Consent
Item
sign written informed consent to participate in the study.
boolean
C0021430 (UMLS CUI [1])
At risk for suicide | Feeling suicidal MADRS
Item
have a significant risk of suicide according to the investigator's opinion or presents a score of 5 or greater on item 10 (suicidal thoughts) of of the madrs
boolean
C0563664 (UMLS CUI [1])
C0424000 (UMLS CUI [2,1])
C4054475 (UMLS CUI [2,2])
Manic episode | Hypomanic episode | Psychotic symptom | Psychotic Disorders | Substance Use Disorders | Substance Dependence
Item
meets dsm-iv-tr criteria for past or current manic or hypomanic episode, past or current psychotic symptoms or disorder, and/or has a history of drug or alcohol abuse/dependence within the last 6 months
boolean
C0349208 (UMLS CUI [1])
C1396834 (UMLS CUI [2])
C0871189 (UMLS CUI [3])
C0033975 (UMLS CUI [4])
C0038586 (UMLS CUI [5])
C0038580 (UMLS CUI [6])
Antidepressive Agents | Fluoxetine | Benzodiazepines | Anti-Anxiety Agents | Sedative hypnotics (non-benzodiazepines) | Antipsychotic Agents Oral | Antipsychotic Agents Depot | Serotonin Agents | Triptans | Tryptophan | Tramadol | Herbal medicine Psychoactive | ST. JOHN'S WORT EXTRACT | Kava preparation | Valerian | Ginkgo biloba extract | Psychotropic Drugs | Anticonvulsants | Investigational New Drugs
Item
uses the following disallowed recent or concomitant medication within the specified time periods - any antidepressant or any drug used for augmentation of antidepressant action within the last 2 weeks (5 weeks for fluoxetine) prior to baseline, any benzodiazepines or other anxiolytics within the last week prior to baseline, any non-benzodiazepine hypnotics within the last week prior to baseline, oral antipsychotics within 2 weeks or depot antipsychotics within 6 months prior to baseline, serotonergic medicinal products (for example triptans, tryptophan, tramadol) within the last week prior to baseline, psychoactive herbal remedies (for example st. johns wort, kava kava, valerian, gingko biloba) within the last 2 weeks prior to baseline, any other drug with potential psychotropic effects within the last 2 weeks prior to baseline, any anticonvulsant drug within the last 2 weeks prior to baseline, or any investigational product within 3 months prior to baseline
boolean
C0003289 (UMLS CUI [1])
C0016365 (UMLS CUI [2])
C0005064 (UMLS CUI [3])
C0040616 (UMLS CUI [4])
C3854290 (UMLS CUI [5])
C0040615 (UMLS CUI [6,1])
C1527415 (UMLS CUI [6,2])
C0040615 (UMLS CUI [7,1])
C0086129 (UMLS CUI [7,2])
C0242701 (UMLS CUI [8])
C1567966 (UMLS CUI [9])
C0041249 (UMLS CUI [10])
C0040610 (UMLS CUI [11])
C2240391 (UMLS CUI [12,1])
C0682880 (UMLS CUI [12,2])
C0813171 (UMLS CUI [13])
C0939882 (UMLS CUI [14])
C0795674 (UMLS CUI [15])
C0772125 (UMLS CUI [16])
C0033978 (UMLS CUI [17])
C0003286 (UMLS CUI [18])
C0013230 (UMLS CUI [19])
Cognitive Therapy | Behavior Therapy | Psychotherapy systematic | Cognitive Therapy Planned | Behavior Therapy Planned | Psychotherapy systematic Planned
Item
is currently receiving formal cognitive or behavioural therapy, systematic psychotherapy, or plans to initiate such therapy during the study
boolean
C0009244 (UMLS CUI [1])
C0004933 (UMLS CUI [2])
C0033968 (UMLS CUI [3,1])
C0220922 (UMLS CUI [3,2])
C0009244 (UMLS CUI [4,1])
C1301732 (UMLS CUI [4,2])
C0004933 (UMLS CUI [5,1])
C1301732 (UMLS CUI [5,2])
C0033968 (UMLS CUI [6,1])
C0220922 (UMLS CUI [6,2])
C1301732 (UMLS CUI [6,3])
Depressive Symptoms | Resistant to Antidepressant therapy Quantity
Item
current depressive symptoms of the patient are considered by the investigator to have been resistant to two well-conducted antidepressant treatments of at least 6 weeks duration
boolean
C0086132 (UMLS CUI [1])
C0332325 (UMLS CUI [2,1])
C1096649 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
Illness Serious | Illness Sequelae Serious | Hepatic Insufficiency | Renal Insufficiency | Cardiovascular Disease | Lung disease | Gastrointestinal Disease | Endocrine System Disease | Nervous system disorder | Epilepsy | Communicable Disease | Neoplastic disease | Metabolic Disease
Item
has a serious illness or serious sequelae thereof, including liver or renal insufficiency, or a cardiovascular, pulmonary, gastrointestinal, endocrine, neurological (including epilepsy), infectious, neoplastic, or metabolic disturbance (if there is a history of such disease but the condition has been stable for at least one year and is judged by the investigator not to render inclusion unsafe and not to interfere with the patient's participation in the study, the patient may be included.)
boolean
C0221423 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0221423 (UMLS CUI [2,1])
C0243088 (UMLS CUI [2,2])
C0205404 (UMLS CUI [2,3])
C1306571 (UMLS CUI [3])
C1565489 (UMLS CUI [4])
C0007222 (UMLS CUI [5])
C0024115 (UMLS CUI [6])
C0017178 (UMLS CUI [7])
C0014130 (UMLS CUI [8])
C0027765 (UMLS CUI [9])
C0014544 (UMLS CUI [10])
C0009450 (UMLS CUI [11])
C1882062 (UMLS CUI [12])
C0025517 (UMLS CUI [13])