Multiple Sclerosis Participant
Item
multiple sclerosis participants
boolean
C0026769 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
Multiple Sclerosis Primary | Multiple Sclerosis Secondary | Multiple Sclerosis, Relapsing-Remitting | Relapsing-Remitting Multiple Sclerosis Average Relapse Frequency
Item
diagnosis of primary, secondary, or relapsing-remitting ms by a neurologist. over 85% of the patient populations that come from the study sites demonstrate relapsing-remitting ms with an average relapse frequency of once every 3 years.
boolean
C0026769 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C0026769 (UMLS CUI [2,1])
C0175668 (UMLS CUI [2,2])
C0751967 (UMLS CUI [3])
C0751967 (UMLS CUI [4,1])
C1510992 (UMLS CUI [4,2])
C0035020 (UMLS CUI [4,3])
C0439603 (UMLS CUI [4,4])
Parkinson Disease Participant
Item
parkinson's disease participants
boolean
C0030567 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
Hoehn and Yahr Stage
Item
hoehn & yahr, stage ii and iii as indicated by certified movement disorders neurologist
boolean
C3639483 (UMLS CUI [1])
Participant All
Item
all participants
boolean
C0681850 (UMLS CUI [1,1])
C0444868 (UMLS CUI [1,2])
Age
Item
between 35 and 80 years of age
boolean
C0001779 (UMLS CUI [1])
Non-smoker | Tobacco use Absent Duration
Item
non-smoking or no smoking within the previous five years
boolean
C0337672 (UMLS CUI [1])
C0543414 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
Malignant Head and Neck Neoplasm Absent | Asthma Absent | Chronic Obstructive Airway Disease Absent | Hypertension untreated Absent
Item
no history of head and neck cancer, asthma or copd, untreated hypertension
boolean
C0278996 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0004096 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0024117 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C0745134 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
Muscle Strength Facial Sufficient
Item
sufficient facial muscle strength so as to achieve and maintain adequate lip closure around a circular mouthpiece
boolean
C0517349 (UMLS CUI [1,1])
C0015450 (UMLS CUI [1,2])
C0205410 (UMLS CUI [1,3])
Cognition normal Mini-mental state examination | Absence Neurologic conditions Negative Respiratory Muscles | Absence Neurologic conditions Negative Gas exchange status | Exception Multiple Sclerosis | Exception Parkinson Disease
Item
cognition within normal limits as determined by the: mini mental status exam (mmse; 1975no neurological (other than ms or pd) condition which adversely affects respiratory muscle or gas exchange system
boolean
C2712133 (UMLS CUI [1,1])
C0451306 (UMLS CUI [1,2])
C0332197 (UMLS CUI [2,1])
C4489311 (UMLS CUI [2,2])
C1513916 (UMLS CUI [2,3])
C0035231 (UMLS CUI [2,4])
C0332197 (UMLS CUI [3,1])
C4489311 (UMLS CUI [3,2])
C1513916 (UMLS CUI [3,3])
C0518226 (UMLS CUI [3,4])
C1705847 (UMLS CUI [4,1])
C0026769 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C0030567 (UMLS CUI [5,2])
Motor Evoked Potentials Reduced
Item
reduced mep's compared to published normative data for age and sex
boolean
C0282617 (UMLS CUI [1,1])
C0392756 (UMLS CUI [1,2])
Decreased peak expiratory flow rate | Young Adult | Middle Aged | Elderly
Item
reduced expiratory peak flow rates (6-8 l/s for young to middle age adults and 3.6 l/s for 65 and older) during voluntary cough production for age and sex (bolser, personal communication; smith-hammond & goldstein, 2006)
boolean
C0520843 (UMLS CUI [1])
C0238598 (UMLS CUI [2])
C0205847 (UMLS CUI [3])
C0001792 (UMLS CUI [4])
Symptoms Relationship Impaired ability to swallow
Item
participant report of symptoms related to swallow impairment
boolean
C1457887 (UMLS CUI [1,1])
C0439849 (UMLS CUI [1,2])
C4061143 (UMLS CUI [1,3])
Deep Brain Stimulation | Chronic Obstructive Airway Disease | Asthma | Tobacco use
Item
dbs copd asthma smoking or smoking within preceding 5 years
boolean
C0394162 (UMLS CUI [1])
C0024117 (UMLS CUI [2])
C0004096 (UMLS CUI [3])
C0543414 (UMLS CUI [4])