Age
Item
age 18 years and older.
boolean
C0001779 (UMLS CUI [1])
Handedness Edinburgh Handedness Inventory
Item
right hand dominant (edinburgh handedness quotient greater than 60).
boolean
C0023114 (UMLS CUI [1,1])
C2737250 (UMLS CUI [1,2])
Informed Consent
Item
able to provide consent for the protocol.
boolean
C0021430 (UMLS CUI [1])
Parkinson Disease de novo Hoehn and Yahr Stage | Parkinson Disease Advanced Hoehn and Yahr Stage
Item
hoehn & yahr stages: i - iii (de novo pd patients); ii - iv (advanced pd patients).
boolean
C0030567 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C3639483 (UMLS CUI [1,3])
C0030567 (UMLS CUI [2,1])
C0205179 (UMLS CUI [2,2])
C3639483 (UMLS CUI [2,3])
Antiparkinson Agents Absent | Parkinson Disease de novo
Item
never treated with antiparkinsonian medications (de novo pd patients).
boolean
C0003405 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0030567 (UMLS CUI [2,1])
C1515568 (UMLS CUI [2,2])
Antiparkinson Agents Discontinue Able | Parkinson Disease Advanced | Withdrawal Overnight
Item
able to go off of antiparkinsonian medications for a minimum 14 hours (advanced pd patients), i.e. overnight withdrawal until after the experiments are completed here at nih.
boolean
C0003405 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C0085732 (UMLS CUI [1,3])
C0030567 (UMLS CUI [2,1])
C0205179 (UMLS CUI [2,2])
C2349954 (UMLS CUI [3,1])
C0439583 (UMLS CUI [3,2])
Other medical condition | Operative Surgical Procedures | Nervous system disorder | Mental condition | Exception Parkinson Disease
Item
patients with any other medical, surgical, neurological or psychiatric conditions except pd.
boolean
C3843040 (UMLS CUI [1])
C0543467 (UMLS CUI [2])
C0027765 (UMLS CUI [3])
C3840291 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C0030567 (UMLS CUI [5,2])
Wearing off effect Symptomatic
Item
patients with known symptomatic wearing off.
boolean
C1504539 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
Pregnancy
Item
pregnant women.
boolean
C0032961 (UMLS CUI [1])
Tricyclic Antidepressive Agents | Antipsychotic Agents | Pharmaceutical Preparations Lowered convulsive threshold | Exception Antiparkinson Agents
Item
concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs other than antiparkinsonian agents that could lower the seizure threshold.
boolean
C0003290 (UMLS CUI [1])
C0040615 (UMLS CUI [2])
C0013227 (UMLS CUI [3,1])
C0234976 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0003405 (UMLS CUI [4,2])
Foreign Bodies Implanted | Artificial cardiac pacemaker | Pump Implanted | Metal plates Skull | Metal Skull | Metal in eye region | Exception Dental appliances | Exception Tooth filling | Cardiac Catheters
Item
persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded.
boolean
C0016542 (UMLS CUI [1,1])
C0021102 (UMLS CUI [1,2])
C0030163 (UMLS CUI [2])
C0182537 (UMLS CUI [3,1])
C0021102 (UMLS CUI [3,2])
C0013866 (UMLS CUI [4,1])
C2951888 (UMLS CUI [4,2])
C0025552 (UMLS CUI [5,1])
C2951888 (UMLS CUI [5,2])
C0562528 (UMLS CUI [6])
C1705847 (UMLS CUI [7,1])
C0441319 (UMLS CUI [7,2])
C1705847 (UMLS CUI [8,1])
C0178866 (UMLS CUI [8,2])
C0179724 (UMLS CUI [9])
Epilepsy
Item
patients with history of seizure disorder or epilepsy.
boolean
C0014544 (UMLS CUI [1])
Informed Consent Unable
Item
subjects without the capacity to give informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Study Subject Participation Status At risk | Study Subject Participation Status Causing Stress | Fatigue Excessive | Frailty General | Apprehension Excessive
Item
if participation in the study would, in the opinion of the investigators, cause undue risk or stress for reasons such as excessive fatigue, general frailty, or excessive apprehension.
boolean
C2348568 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2,1])
C0678227 (UMLS CUI [2,2])
C0038435 (UMLS CUI [2,3])
C0015672 (UMLS CUI [3,1])
C0442802 (UMLS CUI [3,2])
C0424594 (UMLS CUI [4,1])
C0205246 (UMLS CUI [4,2])
C0233485 (UMLS CUI [5,1])
C0442802 (UMLS CUI [5,2])