Japanese | Age
Item
japanese male or female, age 35-65 (part 1), age 35-75 (part 2)
boolean
C1556094 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Osteoarthritis, Knee
Item
diagnosis of osteoarthritis (oa) of the knee based on american college of rheumatology criteria
boolean
C0409959 (UMLS CUI [1])
Knee pain | Knee Osteoarthritis Kellgren-Lawrence score Radiography
Item
knee pain, and radiographic evidence of knee oa (kellgren-lawrence x-ray grade ≥2) obtained within 1 year of enrollment
boolean
C0231749 (UMLS CUI [1])
C0409959 (UMLS CUI [2,1])
C3177117 (UMLS CUI [2,2])
C0034571 (UMLS CUI [2,3])
Age | Morning stiffness Duration | Joint crepitus | Knee Osteoarthritis Involving Index Tibiofemoral joint | Knee Osteoarthritis Disease length
Item
at least one of the following: age >50, morning stiffness <30 minutes in duration, crepitus, and oa of the knee must involve the index tibiofemoral joint and must have present for at least 6 months
boolean
C0001779 (UMLS CUI [1])
C0457086 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
C0231592 (UMLS CUI [3])
C0409959 (UMLS CUI [4,1])
C1314939 (UMLS CUI [4,2])
C2986546 (UMLS CUI [4,3])
C0447795 (UMLS CUI [4,4])
C0409959 (UMLS CUI [5,1])
C0872146 (UMLS CUI [5,2])
Unwilling Analgesics Except Opiates | Analgesics Except Opiates failed | Invasive procedure intended | Intra-Articular Injections | Knee Arthroplasty | Operative procedure on knee Total
Item
patients who meet at least one of the following: unwilling to take non-opiate pain medications, or for whom non-opiate pain medications have failed, or are candidates for or seeking invasive interventions such as intraarticular injections, knee arthroplasty, or total knee surgery
boolean
C0558080 (UMLS CUI [1,1])
C0002771 (UMLS CUI [1,2])
C0332300 (UMLS CUI [1,3])
C0376196 (UMLS CUI [1,4])
C0002771 (UMLS CUI [2,1])
C0332300 (UMLS CUI [2,2])
C0376196 (UMLS CUI [2,3])
C0231175 (UMLS CUI [2,4])
C4048276 (UMLS CUI [3,1])
C1283828 (UMLS CUI [3,2])
C0021488 (UMLS CUI [4])
C0086511 (UMLS CUI [5])
C0187769 (UMLS CUI [6,1])
C0439810 (UMLS CUI [6,2])
Pain level Study Protocol Required
Item
pain levels as required by the protocol at screening and baseline
boolean
C0518087 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C1514873 (UMLS CUI [1,3])
Rheumatoid Arthritis | Arthritis | Gout | Paget Disease | Disease Interferes with Pain assessment | Disease Interferes with Symptom Assessment Osteoarthritis
Item
diagnosis or history of ra, any inflammatory arthritis, gout, paget's disease or any other disease that in the investigator's opinion would interfere with the assessment of pain and other symptoms of oa
boolean
C0003873 (UMLS CUI [1])
C0003864 (UMLS CUI [2])
C0018099 (UMLS CUI [3])
C1368019 (UMLS CUI [4])
C0012634 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0030198 (UMLS CUI [5,3])
C0012634 (UMLS CUI [6,1])
C0521102 (UMLS CUI [6,2])
C3494437 (UMLS CUI [6,3])
C0029408 (UMLS CUI [6,4])
Regional pain syndrome Suggestive of Fibromyalgia | Pain regional caused by LUMBAR SPINAL CORD COMPRESSION | Pain regional caused by Cervical cord compression | Radiculopathy | At risk Radiculopathy
Item
patients with regional pain syndromes suggestive of fibromyalgia or regional pain caused by lumbar or cervical compressions with radiculopathy or at risk of developing radiculopathy.
boolean
C0850603 (UMLS CUI [1,1])
C0332299 (UMLS CUI [1,2])
C0016053 (UMLS CUI [1,3])
C0030193 (UMLS CUI [2,1])
C0205147 (UMLS CUI [2,2])
C0015127 (UMLS CUI [2,3])
C0745990 (UMLS CUI [2,4])
C0030193 (UMLS CUI [3,1])
C0205147 (UMLS CUI [3,2])
C0015127 (UMLS CUI [3,3])
C0852866 (UMLS CUI [3,4])
C0700594 (UMLS CUI [4])
C1444641 (UMLS CUI [5,1])
C0700594 (UMLS CUI [5,2])
Fibromyalgia
Item
diagnosis or history of fibromyalgia
boolean
C0016053 (UMLS CUI [1])
Operative Surgical Procedure Planned
Item
planned surgical procedure during the duration of the study
boolean
C0543467 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])