Idiopathic osteoarthritis | Age | Idiopathic osteoarthritis Tibiofemoral Kellgren-Lawrence score X-ray
Item
primary osteoarthritis patients recruited were between 35 to 60 years of age, with x-ray confirmed kellgren-lawrence grade13 ii or iii severity primary tibiofemoral oa, according to the american college of rheumatology criteria.
boolean
C0409952 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0409952 (UMLS CUI [3,1])
C1269072 (UMLS CUI [3,2])
C3177117 (UMLS CUI [3,3])
C0034571 (UMLS CUI [3,4])
Childbearing Potential Contraceptive methods
Item
women of childbearing age had to provide evidence of adequate contraception prior to inclusion.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Patients Excluded
Item
those patients were excluded from the present study who:
boolean
C0030705 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
Age
Item
were of age less than 35 years or more than 60 years
boolean
C0001779 (UMLS CUI [1])
Gastroduodenal disorder | Hepatic impairment | Renal Insufficiency
Item
presented with active concomitant gastroduodenal disorders, hepatic and renal impairment within last 30 days prior to receiving the study drug
boolean
C3874418 (UMLS CUI [1])
C0948807 (UMLS CUI [2])
C1565489 (UMLS CUI [3])
Arthritis | Gout | Knee Injuries | HIP INJURY TRAUMA | SPINE INJURY TRAUMA | Osteoarthritis of hip | Interference Functional assessment Knee
Item
were diagnosed to have any inflammatory arthritis, gout or acute trauma of the knee, hip or spine; accompanying oa of the hip of sufficient severity to interfere with the functional assessment of the knee
boolean
C0003864 (UMLS CUI [1])
C0018099 (UMLS CUI [2])
C0022744 (UMLS CUI [3])
C0744931 (UMLS CUI [4])
C0748916 (UMLS CUI [5])
C0029410 (UMLS CUI [6])
C0521102 (UMLS CUI [7,1])
C0278372 (UMLS CUI [7,2])
C0022742 (UMLS CUI [7,3])
Pharmacotherapy Oral Osteoarthritis | Glucosamine Sulfate | Chondroitin Sulfates | Diacetylrhein | Piascledine | Antidepressive Agents | Tranquilizing Agents | Antacids | Antibiotics | Cardiac lesion | Hypertensive disease | Pregnancy | Pregnancy, Planned
Item
had previous or ongoing treatment with oral sysdoa (e.g., glucosamine sulphate, chondroitin sulphate, diacerein, piascledine), anti-depressants, tranquillisers, antacids or antibiotics; were having active cardiac lesion or hypertension, were pregnant females and those who were planning their pregnancy during the study
boolean
C0013216 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0029408 (UMLS CUI [1,3])
C0017720 (UMLS CUI [2])
C0008466 (UMLS CUI [3])
C0057678 (UMLS CUI [4])
C0071027 (UMLS CUI [5])
C0003289 (UMLS CUI [6])
C0040614 (UMLS CUI [7])
C0003138 (UMLS CUI [8])
C0003232 (UMLS CUI [9])
C1391976 (UMLS CUI [10])
C0020538 (UMLS CUI [11])
C0032961 (UMLS CUI [12])
C0032992 (UMLS CUI [13])
Hypersensitivity Diclofenac Sodium | Hypersensitivity Diacetylrhein | Hypersensitivity Compound Similar | Hypersensitivity Acetaminophen Excipient | Knee pain Except Osteoarthritis
Item
were having a known hypersensitivity to diclofenac sodium, to diacerein, to similar compounds, to the excipients or paracetamol, have history of painful knee conditions other than oa
boolean
C0020517 (UMLS CUI [1,1])
C0700583 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0057678 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C1706082 (UMLS CUI [3,2])
C2348205 (UMLS CUI [3,3])
C0020517 (UMLS CUI [4,1])
C0000970 (UMLS CUI [4,2])
C0015237 (UMLS CUI [4,3])
C0231749 (UMLS CUI [5,1])
C0332300 (UMLS CUI [5,2])
C0029408 (UMLS CUI [5,3])
Diarrhea persistent | Laxative usage | Gastrointestinal Diseases Severe | Obesity, Morbid | Parenchymal Organ Disease Severe | Anemia | Hemoglobin measurement | Hematocrit level
Item
have persistent diarrhoea or laxative use; severe gastrointestinal disorders, severe obesity, severe parenchymal organ disease, or anaemia (haemoglobin< 10.0 g/ dl or haematocrit < 30%).
boolean
C0743188 (UMLS CUI [1])
C0240170 (UMLS CUI [2])
C0017178 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0028756 (UMLS CUI [4])
C4277702 (UMLS CUI [5,1])
C0178784 (UMLS CUI [5,2])
C0012634 (UMLS CUI [5,3])
C0205082 (UMLS CUI [5,4])
C0002871 (UMLS CUI [6])
C0518015 (UMLS CUI [7])
C0518014 (UMLS CUI [8])
Adrenal Cortex Hormones Oral | Adrenal Cortex Hormones Intramuscular injection | Intraarticular injection of corticosteroids | Adrenal Cortex Hormones Injection of soft tissue | Joint lavage | Arthroscopy
Item
patients who received oral, intramuscular, intraarticular or soft tissue injections of corticosteroids within last eight weeks before receiving the first dose of the study medication, or had undergone joint lavage and arthroscopic procedures in the previous 6 months, were also excluded.
boolean
C0001617 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0001617 (UMLS CUI [2,1])
C0021492 (UMLS CUI [2,2])
C2064783 (UMLS CUI [3])
C0001617 (UMLS CUI [4,1])
C0185357 (UMLS CUI [4,2])
C0022417 (UMLS CUI [5,1])
C0022100 (UMLS CUI [5,2])
C0003904 (UMLS CUI [6])