Knee Osteoarthritis Disease length
Item
participants who have suffered from knee osteoarthritis at least for one year and meet the criteria of american college of rheumatology
boolean
C0409959 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
Meloxicam Dose Stable | Aceclofenac Dosage
Item
participants who are taking stable dose of meloxicam 7.5 milligram (mg) or 15 mg daily or aceclofenac 100 mg twice a day at least for four weeks
boolean
C0083381 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0050403 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
Pain intensity mean Numeric Rating Scale
Item
participants whose mean pain intensity has been 5 or higher on the numeric rating scale (nrs) for the last 48 hours
boolean
C1320357 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C4050142 (UMLS CUI [1,3])
General health Favorable | Medical History | Medication history | Physical Examination | Vital signs | Blood Pressure | Pulse | Laboratory Procedures | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Renal function | Creatinine measurement, serum
Item
participants whose general health conditions are favorable, according to the criteria below: medical and medication history, physical examination before the study medication administration, vital signs: blood pressure, pulse, clinical laboratory tests: serum glutamic oxaloacetic transaminase (sgot)/serum glutamic pyruvate transaminase (sgpt) less-than or equal to (=<) 2 x normal range, renal function: creatinine less than (<) 2.0 milligrams per deciliter (mg/dl)
boolean
C0424575 (UMLS CUI [1,1])
C3640814 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2])
C1553893 (UMLS CUI [3])
C0031809 (UMLS CUI [4])
C0518766 (UMLS CUI [5])
C0005823 (UMLS CUI [6])
C0391850 (UMLS CUI [7])
C0022885 (UMLS CUI [8])
C0201899 (UMLS CUI [9])
C0201836 (UMLS CUI [10])
C0232804 (UMLS CUI [11])
C0201976 (UMLS CUI [12])
Childbearing Potential Contraceptive methods | Childbearing Potential Urine pregnancy test negative
Item
female participants of childbearing potential to use the proper contraceptive methods during the study period (urine pregnancy test prior to the study participation should be negative)
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0430057 (UMLS CUI [2,2])
Study Subject Applicable Kellgren-Lawrence score
Item
participants who are applicable to kellgren and lawrence grade
boolean
C0681850 (UMLS CUI [1,1])
C1706839 (UMLS CUI [1,2])
C3177117 (UMLS CUI [1,3])
Tramadol Unresponsive to Treatment | Tramadol Due to Adverse event | Tramadol Discontinued Due to Adverse event
Item
participants who had failed tramadol treatment before or stopped taking tramadol due to adverse event(s)
boolean
C0040610 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0040610 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0877248 (UMLS CUI [2,3])
C0040610 (UMLS CUI [3,1])
C1444662 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C0877248 (UMLS CUI [3,4])
Rheumatoid Arthritis | Ankylosing spondylitis | Gout | Pseudogout | Fibromyalgia | Anserine bursitis | Major injury Target Joint | Communicable Disease Target Joint | Avascular necrosis Target Joint | Anatomical Deformities Target Joint | Interference Assessment Target Joint | Operative Surgical Procedures Associated with Target Joint | Arthroscopy Associated with Target Joint
Item
participants who are applicable to one of the following conditions: rheumatoid arthritis, ankylosing spondylitis, active gout or active pseudo-gout, diagnosis of fibromyalgia (according to acr criteria), anserine bursitis, major trauma of the target joint within six months prior to the study medication administration, infection of the target joint within six months prior to the study medication administration, apparent avascular necrosis of the target joint within six months prior to the study medication administration, anatomical deformities of the target joint, which may interfere with assessment of the target joint, surgical procedures associated with the target joint within one year prior to the study medication administration, arthroscopic procedures associated with the target joint within six months prior to the study medication administration
boolean
C0003873 (UMLS CUI [1])
C0038013 (UMLS CUI [2])
C0018099 (UMLS CUI [3])
C0033802 (UMLS CUI [4])
C0016053 (UMLS CUI [5])
C2005674 (UMLS CUI [6])
C0332677 (UMLS CUI [7,1])
C1521840 (UMLS CUI [7,2])
C0022417 (UMLS CUI [7,3])
C0009450 (UMLS CUI [8,1])
C1521840 (UMLS CUI [8,2])
C0022417 (UMLS CUI [8,3])
C3887513 (UMLS CUI [9,1])
C1521840 (UMLS CUI [9,2])
C0022417 (UMLS CUI [9,3])
C0302142 (UMLS CUI [10,1])
C1521840 (UMLS CUI [10,2])
C0022417 (UMLS CUI [10,3])
C0521102 (UMLS CUI [11,1])
C1516048 (UMLS CUI [11,2])
C1521840 (UMLS CUI [11,3])
C0022417 (UMLS CUI [11,4])
C0543467 (UMLS CUI [12,1])
C0332281 (UMLS CUI [12,2])
C1521840 (UMLS CUI [12,3])
C0022417 (UMLS CUI [12,4])
C0003904 (UMLS CUI [13,1])
C0332281 (UMLS CUI [13,2])
C1521840 (UMLS CUI [13,3])
C0022417 (UMLS CUI [13,4])
Disease Unstable | Sleep Disorders | Sleep Apnea | Narcolepsy | Dementia | Damage Functional | Disease Causing Malabsorption | Accumulation Excessive | Metabolic Diseases | Excretion Disease
Item
participants who have one of the following diseases: significantly unstable diseases such as sleep disorder (e.g., sleep apnea or narcolepsy) or dementia, functional damage or disease which may cause malabsorption, excessive accumulation, or metabolism or excretion disorder
boolean
C0012634 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0851578 (UMLS CUI [2])
C0037315 (UMLS CUI [3])
C0027404 (UMLS CUI [4])
C0497327 (UMLS CUI [5])
C1883709 (UMLS CUI [6,1])
C0205245 (UMLS CUI [6,2])
C0012634 (UMLS CUI [7,1])
C0678227 (UMLS CUI [7,2])
C3714745 (UMLS CUI [7,3])
C4055506 (UMLS CUI [8,1])
C0442802 (UMLS CUI [8,2])
C0025517 (UMLS CUI [9])
C0221102 (UMLS CUI [10,1])
C0012634 (UMLS CUI [10,2])
Pregnancy | Breast Feeding
Item
participants who are pregnant or breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])