Obesity | Body mass index
Item
obese (bmi >/= 30)
boolean
C0028754 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
Insulin Resistance Homeostasis model assessment
Item
insulin resistant (homa-ir >/= 2.1)
boolean
C0021655 (UMLS CUI [1,1])
C1829779 (UMLS CUI [1,2])
Patients Genotype Number
Item
genotype 3 patients
boolean
C0030705 (UMLS CUI [1,1])
C0017431 (UMLS CUI [1,2])
C0237753 (UMLS CUI [1,3])
Pregnancy | Breast Feeding
Item
women with ongoing pregnancy or who are breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Liver disease | Liver disease Viral | Alcoholic Liver Disease | Liver disease Drug-induced | Autoimmune liver disease | Liver disease Metabolic | Liver disease Genetic
Item
patients with any other other underlying liver disease (viral, alcoholic, druginduced, autoimmune, metabolic, genetic).
boolean
C0023895 (UMLS CUI [1])
C0023895 (UMLS CUI [2,1])
C0521026 (UMLS CUI [2,2])
C0023896 (UMLS CUI [3])
C0023895 (UMLS CUI [4,1])
C0458082 (UMLS CUI [4,2])
C0400936 (UMLS CUI [5])
C0023895 (UMLS CUI [6,1])
C0311400 (UMLS CUI [6,2])
C0023895 (UMLS CUI [7,1])
C0314603 (UMLS CUI [7,2])
Antiviral Therapy | Therapeutic procedure Discontinued
Item
patients currently on antiviral therapy, or who have ceased therapy within 6 months of recruitment to the study.
boolean
C0280274 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C1444662 (UMLS CUI [2,2])
Causes Insulin Resistance | Glucocorticoids | Catecholamines | Growth Hormone | Polycystic Ovary Syndrome
Item
patients with other causes for insulin resistance e.g., excess counter-regulatory hormones: glucocorticoids, catecholamines, growth hormone, polycystic ovary syndrome).
boolean
C0015127 (UMLS CUI [1,1])
C0021655 (UMLS CUI [1,2])
C0017710 (UMLS CUI [2])
C0007412 (UMLS CUI [3])
C0037663 (UMLS CUI [4])
C0032460 (UMLS CUI [5])
Steroids Affecting Insulin Resistance | Pharmaceutical Preparations Affecting Insulin Resistance | Steroids Unable to discontinue | Pharmaceutical Preparations Unable to discontinue
Item
patients on steroids or other drug that affects insulin resistance, which are unable to be stopped for 3 days prior to ir testing.
boolean
C0038317 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0021655 (UMLS CUI [1,3])
C0013227 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0021655 (UMLS CUI [2,3])
C0038317 (UMLS CUI [3,1])
C1548265 (UMLS CUI [3,2])
C0013227 (UMLS CUI [4,1])
C1548265 (UMLS CUI [4,2])
Diabetes mellitus, overt | Plasma fasting glucose measurement
Item
patients with overt diabetes (based on results of fasting plasma glucose) will be excluded from participation as we are focusing on insulin resistance in the absence of diabetes.
boolean
C0543567 (UMLS CUI [1])
C0583513 (UMLS CUI [2])
Condition Excludes Increase Physical activity
Item
conditions which preclude a sudden increase in physical activity:
boolean
C0348080 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
C0442805 (UMLS CUI [1,3])
C0026606 (UMLS CUI [1,4])
Chronic lung disease Associated with Functional Limitation
Item
history or other evidence of chronic pulmonary disease associated with functional limitation.
boolean
C0746102 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C4542603 (UMLS CUI [1,3])
Heart Disease Severe New York Heart Association Classification | Myocardial Infarction | Ventricular Tachycardia Treatment required for | Angina, Unstable | Cardiovascular Diseases
Item
history of severe cardiac disease (e.g., nyha functional class iii or iv, myocardial infarction within 6 months, ventricular tachyarrhythmias requiring ongoing treatment, unstable angina or other significant cardiovascular diseases).
boolean
C0018799 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1275491 (UMLS CUI [1,3])
C0027051 (UMLS CUI [2])
C0042514 (UMLS CUI [3,1])
C0332121 (UMLS CUI [3,2])
C0002965 (UMLS CUI [4])
C0007222 (UMLS CUI [5])
Lacking Able to walk Number of steps per day | Physical disability | Obesity, Morbid
Item
unable to 10000 steps/day eg physical disability, morbid obesity.
boolean
C0332268 (UMLS CUI [1,1])
C2712089 (UMLS CUI [1,2])
C1651669 (UMLS CUI [1,3])
C0439505 (UMLS CUI [1,4])
C0520817 (UMLS CUI [2])
C0028756 (UMLS CUI [3])
Substance Use Disorders | Alcohol consumption Gram per day | Gender
Item
evidence of ongoing substance use (including alcohol consumption >20g/day for men and >10g/day for women) within one year of study recruitment.
boolean
C0038586 (UMLS CUI [1])
C0001948 (UMLS CUI [2,1])
C0439417 (UMLS CUI [2,2])
C0079399 (UMLS CUI [3])
Poor venous access
Item
poor veins (inadequate venous access)
boolean
C0577866 (UMLS CUI [1])
Informed Consent Unable | Informed Consent Unwilling | Protocol Compliance Unable | Protocol Compliance Unwilling | Mental Disorders, Severe | Living place Remote | Time commitment
Item
inability or unwillingness to provide informed consent or abide by study requirements eg severe psychiatric illness, lives remotely, time commitment.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
C0525058 (UMLS CUI [3,1])
C1299582 (UMLS CUI [3,2])
C0525058 (UMLS CUI [4,1])
C0558080 (UMLS CUI [4,2])
C4046029 (UMLS CUI [5])
C0337646 (UMLS CUI [6,1])
C0205157 (UMLS CUI [6,2])
C0040223 (UMLS CUI [7,1])
C0870312 (UMLS CUI [7,2])