Non-Small Cell Lung Carcinoma Advanced TNM clinical staging | Ineligibility Chemoradiotherapy | Non-Small Cell Lung Carcinoma TNM clinical staging | Non-small cell lung cancer recurrent
Item
histologically or cytologically documented nsclc with advanced disease (stage iiib not eligible for chemoradiotherapy or stage iv or recurrent disease)
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
C1512714 (UMLS CUI [2,1])
C0436307 (UMLS CUI [2,2])
C0007131 (UMLS CUI [3,1])
C3258246 (UMLS CUI [3,2])
C0278517 (UMLS CUI [4])
Organ function Laboratory tests
Item
adequate organ function as assessed by laboratory tests
boolean
C0678852 (UMLS CUI [1,1])
C0022885 (UMLS CUI [1,2])
Evaluable Disease | Measurable Disease
Item
evaluable disease or disease measurable per response evaluation criteria in solid tumors (recist)
boolean
C1516986 (UMLS CUI [1])
C1513041 (UMLS CUI [2])
Cancer treatment Quantity Non-Small Cell Lung Carcinoma Advanced | Chemotherapy | Therapeutic radiology procedure
Item
more than one anti-cancer regimen (chemotherapy or radiotherapy) for advanced nsclc prior to initiation of study treatment
boolean
C0920425 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0007131 (UMLS CUI [1,3])
C0205179 (UMLS CUI [1,4])
C0392920 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
Cancer treatment Adjuvant | Cancer treatment Neoadjuvant
Item
any adjuvant or neoadjuvant anti-cancer therapy within a specified timeframe prior to first study treatment
boolean
C0920425 (UMLS CUI [1,1])
C1522673 (UMLS CUI [1,2])
C0920425 (UMLS CUI [2,1])
C0600558 (UMLS CUI [2,2])
Fasting hyperglycaemia CTCAE Grades | Diabetes Mellitus Requirement Pharmaceutical Preparations Regular
Item
history of grade >= 3 fasting hyperglycemia or diabetes requiring regular medication
boolean
C2609269 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
C0011849 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0013227 (UMLS CUI [2,3])
C0205272 (UMLS CUI [2,4])
Autoimmune Disease | Communicable Disease Requirement Antibiotics Intravenous | Illness Uncontrolled
Item
active autoimmune disease, active infection requiring iv antibiotics, or other current uncontrolled illness
boolean
C0004364 (UMLS CUI [1])
C0009450 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0003232 (UMLS CUI [2,3])
C1522726 (UMLS CUI [2,4])
C0221423 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
Cardiac dysfunction | Pulmonary Dysfunction
Item
history of clinically significant cardiac or pulmonary dysfunction
boolean
C3277906 (UMLS CUI [1])
C1709770 (UMLS CUI [2])
Malabsorption Syndrome | Condition Interferes with Intestinal Absorption
Item
history of malabsorption syndrome or other condition that would interfere with enteral absorption
boolean
C0024523 (UMLS CUI [1])
C0348080 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0021826 (UMLS CUI [2,3])
Liver disease
Item
clinically significant history of liver disease
boolean
C0023895 (UMLS CUI [1])
Condition Requirement Anticoagulants Dose Full | Warfarin | Heparin | Fibrinolytic Agents
Item
any condition requiring full-dose anticoagulants, such as warfarin, heparin, or thrombolytic agents
boolean
C0348080 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0003280 (UMLS CUI [1,3])
C0178602 (UMLS CUI [1,4])
C0443225 (UMLS CUI [1,5])
C0043031 (UMLS CUI [2])
C0019134 (UMLS CUI [3])
C0016018 (UMLS CUI [4])
Metastatic malignant neoplasm to brain untreated | Metastatic malignant neoplasm to brain Symptomatic | Metastatic malignant neoplasm to brain Treatment required for
Item
known brain metastases that are untreated, symptomatic, or require therapy
boolean
C0220650 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C0220650 (UMLS CUI [2,1])
C0231220 (UMLS CUI [2,2])
C0220650 (UMLS CUI [3,1])
C0332121 (UMLS CUI [3,2])
Pregnancy | Lactation | Breast Feeding
Item
pregnancy, lactation, or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0022925 (UMLS CUI [2])
C0006147 (UMLS CUI [3])