Nasopharyngeal Nonkeratinizing Differentiated Carcinoma | Undifferentiated carcinoma of nasopharynx
Item
histologically proven differentiated non-keratinizing carcinoma, and undifferentiated carcinoma of the nasopharynx.
boolean
C1709153 (UMLS CUI [1])
C0279748 (UMLS CUI [2])
TNM clinical staging
Item
stage ⅳab disease
boolean
C3258246 (UMLS CUI [1])
Karnofsky Performance Status
Item
kps >70
boolean
C0206065 (UMLS CUI [1])
Age
Item
age between 18-70
boolean
C0001779 (UMLS CUI [1])
Bone Marrow function | Absolute neutrophil count Peripheral blood | Platelet Count measurement | Pretreatment Without Intervention | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Creatinine measurement, serum | Creatinine clearance measurement
Item
patients should have adequate bone marrow function defined as an absolute peripheral granulocyte count (agc) of > 2000 cells/mm3, platelet count of > 100,000 cells/mm3 (pre treatment without intervention). bilirubin < 1.5 mg/dl, ast or alt<2 x upper normal, serum creatinine<1.5mg/dl, creatinine clearance >50ml/min.
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0948762 (UMLS CUI [2,1])
C0229664 (UMLS CUI [2,2])
C0032181 (UMLS CUI [3])
C3539076 (UMLS CUI [4,1])
C0332288 (UMLS CUI [4,2])
C0184661 (UMLS CUI [4,3])
C1278039 (UMLS CUI [5])
C0201899 (UMLS CUI [6])
C0201836 (UMLS CUI [7])
C0201976 (UMLS CUI [8])
C0373595 (UMLS CUI [9])
Radiation therapy to the head and neck Absent | Prior Chemotherapy Absent
Item
no prior radiation treatment to the head and neck or any prior chemotherapy
boolean
C4540910 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1514457 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Malignant Neoplasms Previous Absent | Exception Basal cell carcinoma
Item
patients with no prior malignancy (not include basal cell carcinoma of skin)
boolean
C0006826 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
Neoplasm Metastasis below Clavicle Clinical examination | Distant metastasis Clinical examination | Neoplasm Metastasis below Clavicle Radiography | Distant metastasis Radiography
Item
evidence of metastases (below the clavicle or distant) by clinical or radiographic examinations.
boolean
C0027627 (UMLS CUI [1,1])
C0542339 (UMLS CUI [1,2])
C0008913 (UMLS CUI [1,3])
C1456356 (UMLS CUI [1,4])
C1269798 (UMLS CUI [2,1])
C1456356 (UMLS CUI [2,2])
C0027627 (UMLS CUI [3,1])
C0542339 (UMLS CUI [3,2])
C0008913 (UMLS CUI [3,3])
C0043299 (UMLS CUI [3,4])
C1269798 (UMLS CUI [4,1])
C0043299 (UMLS CUI [4,2])
Radiation therapy to the head and neck Reason Any
Item
prior radiotherapy to the head and neck region for any reason.
boolean
C4540910 (UMLS CUI [1,1])
C0392360 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
Operative Surgical Procedures Initial | Exception Biopsy Primary tumor site | Exception Biopsy Disorder of neck
Item
initial surgical treatment excluding diagnostic biopsy of the primary site or neck disease.
boolean
C0543467 (UMLS CUI [1,1])
C0205265 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0005558 (UMLS CUI [2,2])
C0475447 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0005558 (UMLS CUI [3,2])
C0558385 (UMLS CUI [3,3])
Primary tumor | Exception Basal cell carcinoma | Exception Squamous cell carcinoma of skin
Item
patients with previous or simultaneous primaries, excluding basal cell carcinoma or squamous cell carcinoma of skin.
boolean
C0677930 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0553723 (UMLS CUI [3,2])
Pregnancy
Item
pregnant women
boolean
C0032961 (UMLS CUI [1])