Age
Item
subjects 21 to 80 years old (inclusive).
boolean
C0001779 (UMLS CUI [1])
Heart failure Ischemic New York Heart Association Classification
Item
subjects with functional class (nyha) ii or iii ischemic heart failure.
boolean
C0018801 (UMLS CUI [1,1])
C0475224 (UMLS CUI [1,2])
C1275491 (UMLS CUI [1,3])
Therapeutic procedure cardiac optimal | Nitrates Active Long-term | Adrenergic beta-Antagonists Maximal | Angiotensin-Converting Enzyme Inhibitors | Symptoms Uncontrolled
Item
subjects who have attempted "best" cardiac medical therapy including long-acting nitrates, maximal use of beta-adrenergic blocking agents, and angiotensin-converting enzyme (ace)inhibitors without control of symptoms.
boolean
C0087111 (UMLS CUI [1,1])
C0018787 (UMLS CUI [1,2])
C2698651 (UMLS CUI [1,3])
C0028125 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0443252 (UMLS CUI [2,3])
C0001645 (UMLS CUI [3,1])
C0205289 (UMLS CUI [3,2])
C0003015 (UMLS CUI [4])
C1457887 (UMLS CUI [5,1])
C0205318 (UMLS CUI [5,2])
Patients Inappropriate Revascularization conventional
Item
subjects must be identified as non-candidates for conventional revascularization by their referring cardiologist.
boolean
C0030705 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])
C0581603 (UMLS CUI [1,3])
C0439858 (UMLS CUI [1,4])
Left ventricular ejection fraction Echocardiography
Item
subjects must have left ventricular ejection fraction <40% by echocardiography.
boolean
C0428772 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
Anatomy Coronary Coronary angiography | Coronary Artery Disease Inappropriate Standard Revascularization
Item
all subjects must have a recent coronary angiogram (within the last 6 months) to document the coronary anatomy and insure the presence of coronary disease that is not amenable to standard revascularization procedures.
boolean
C0700276 (UMLS CUI [1,1])
C1522318 (UMLS CUI [1,2])
C0085532 (UMLS CUI [1,3])
C1956346 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
C1442989 (UMLS CUI [2,3])
C0581603 (UMLS CUI [2,4])
Serum Brain natriuretic peptide measurement
Item
have serum b-type natriuretic peptide (bnp) level >100 pg/ml.
boolean
C0229671 (UMLS CUI [1,1])
C1095989 (UMLS CUI [1,2])
Myocardial Infarction | Q wave MI | Non-Q wave MI | CKMB Increased
Item
myocardial infarction (q wave or non-q wave defined as ckmb >3 times normal) within 30 days of treatment.
boolean
C0027051 (UMLS CUI [1])
C0861151 (UMLS CUI [2])
C0860155 (UMLS CUI [3])
C0010290 (UMLS CUI [4,1])
C0205217 (UMLS CUI [4,2])
Coronary revascularisation Successful
Item
successful coronary revascularization procedures within 3 months of study enrollment.
boolean
C0877341 (UMLS CUI [1,1])
C1272703 (UMLS CUI [1,2])
Cerebrovascular accident | Transient Ischemic Attack
Item
documented stroke or transient ischemic attack (tia) within 60 days of study enrollment.
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
Heart failure New York Heart Association Classification | Heart failure idiopathic | Heart failure Without Feature Ischemic
Item
nyha class iv heart failure and patients with idiopathic or non-ischemic heart failure.
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0018801 (UMLS CUI [2,1])
C0332240 (UMLS CUI [2,2])
C0018801 (UMLS CUI [3,1])
C0332288 (UMLS CUI [3,2])
C2348519 (UMLS CUI [3,3])
C0475224 (UMLS CUI [3,4])
Aortic stenosis, severe | Aortic valve area Size | Aortic Valve Insufficiency Severe | Mitral Valve Stenosis Severe | Mitral valve area Size | Mitral Valve Insufficiency Severe
Item
history of severe aortic stenosis (aortic valve area < 1.0 cm2) or insufficiency (>2+); severe mitral stenosis (mitral valve area <1.5 cm2); or severe mitral insufficiency(>2+).
boolean
C3806272 (UMLS CUI [1])
C0428817 (UMLS CUI [2,1])
C0456389 (UMLS CUI [2,2])
C0003504 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0026269 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0428818 (UMLS CUI [5,1])
C0456389 (UMLS CUI [5,2])
C0026266 (UMLS CUI [6,1])
C0205082 (UMLS CUI [6,2])
Biventricular pacemaker insertion
Item
implantation of biventricular pacemaker within 90 days of study treatment.
boolean
C3805138 (UMLS CUI [1])
Comorbidity Severe | Reduced life expectancy | Chronic disease | Severe chronic obstructive pulmonary disease | Kidney Failure | Malignant Neoplasms
Item
severe co-morbidity associated with a reduction in life expectancy of less than 1 year, such as chronic medical illness (i.e. severe chronic obstructive pulmonary disease, renal failure or cancer).
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1858274 (UMLS CUI [2])
C0008679 (UMLS CUI [3])
C0730607 (UMLS CUI [4])
C0035078 (UMLS CUI [5])
C0006826 (UMLS CUI [6])