Multiple Sclerosis EDSS
Item
1. clinical diagnosis of ms by mcdonald criteria (mcdonald, compston et al. 2001). edss level between 3.5-5.5, who report ambulation problems.
boolean
C0026769 (UMLS CUI [1,1])
C0451246 (UMLS CUI [1,2])
Age
Item
2. men and women between the ages 18-75 years.
boolean
C0001779 (UMLS CUI [1])
Foot-drop Unilateral
Item
3. presence of unilateral foot drop that is clinically apparent to the pi or pi designate.
boolean
C0085684 (UMLS CUI [1,1])
C0205092 (UMLS CUI [1,2])
Able to walk Without Walking aid | Able to walk Feet Quantity
Item
4. must be able to ambulate 25 feet without an assisting device
boolean
C2712089 (UMLS CUI [1,1])
C0332288 (UMLS CUI [1,2])
C0557834 (UMLS CUI [1,3])
C2712089 (UMLS CUI [2,1])
C0347981 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
Exclusion Criteria Cardiovascular | Myocardial Infarction | Uncontrolled hypertension | Diabetic - poor control
Item
1. cardiovascular: recent mi < 4 wk, uncontrolled htn >190/110 mmhg, history of uncontrolled diabetes.
boolean
C0680251 (UMLS CUI [1,1])
C3887460 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2])
C1868885 (UMLS CUI [3])
C0421258 (UMLS CUI [4])
Symptoms Orthostasis Standing up
Item
2. symptoms of orthostasis when standing up.
boolean
C1457887 (UMLS CUI [1,1])
C0149746 (UMLS CUI [1,2])
C0444796 (UMLS CUI [1,3])
Circulation problem | Claudication Vascular | Pitting edema
Item
3. circulatory problems, history of vascular claudication or pitting edema.
boolean
C0848724 (UMLS CUI [1])
C1456822 (UMLS CUI [2,1])
C1801960 (UMLS CUI [2,2])
C0333243 (UMLS CUI [3])
Instructions Comprehension Unable | Protocol Compliance Unable
Item
4. unable to fully understand instructions in order to use the equipment or the process of the study.
boolean
C1442085 (UMLS CUI [1,1])
C0162340 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C0525058 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
Body Weight
Item
5. body weight over 150 kg.
boolean
C0005910 (UMLS CUI [1])
Leg Injuries Limitation of joint movement | Leg Injuries Limited function
Item
6. lower extremity injuries that limit range of motion or function.
boolean
C0023220 (UMLS CUI [1,1])
C0231589 (UMLS CUI [1,2])
C0023220 (UMLS CUI [2,1])
C1331405 (UMLS CUI [2,2])
Joint problem Limitation of joint movement | Joint problem Causing Movement pain | Hip Joint Problem | Joint of lower extremity Problem | Treatment Resistant
Item
7. joint problems (hip or leg) that limit range of motion or cause pain with movement despite treatment.
boolean
C0575044 (UMLS CUI [1,1])
C0231589 (UMLS CUI [1,2])
C0575044 (UMLS CUI [2,1])
C0678227 (UMLS CUI [2,2])
C0240386 (UMLS CUI [2,3])
C0019558 (UMLS CUI [3,1])
C0033213 (UMLS CUI [3,2])
C0584731 (UMLS CUI [4,1])
C0033213 (UMLS CUI [4,2])
C0087111 (UMLS CUI [5,1])
C0332325 (UMLS CUI [5,2])
Unstable fracture
Item
8. unstable fractures.
boolean
C0559876 (UMLS CUI [1])
Pressure Ulcer | Broken skin | Other Coding
Item
9. pressure sores with any skin breakdown in areas in contact with the body harness or lokomat apparatus.
boolean
C0011127 (UMLS CUI [1])
C0150077 (UMLS CUI [2])
C3846158 (UMLS CUI [3])
Substance Use Disorders chronic
Item
10. chronic and ongoing alcohol or drug abuse.
boolean
C0038586 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
Premorbidity Depressive disorder | Premorbidity Psychotic Disorders
Item
11. pre-morbid, ongoing depression or psychosis.
boolean
C0871122 (UMLS CUI [1,1])
C0011581 (UMLS CUI [1,2])
C0871122 (UMLS CUI [2,1])
C0033975 (UMLS CUI [2,2])
Physical therapy
Item
12. ongoing physical therapy.
boolean
C0949766 (UMLS CUI [1])