Central neuropathic pain Due to Multiple Sclerosis
Item
have central neuropathic pain due to multiple sclerosis (ms) based on the disease diagnostic criteria
boolean
C4087506 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Adult
Item
adult males or females
boolean
C0001675 (UMLS CUI [1])
Pain score Average 24 Hours Daily
Item
have a score of 4 or greater on the daily 24-hour average pain score
boolean
C0582148 (UMLS CUI [1,1])
C1510992 (UMLS CUI [1,2])
C1442770 (UMLS CUI [1,3])
C0332173 (UMLS CUI [1,4])
Gender Pregnancy test negative
Item
females must test negative for pregnancy at study entry
boolean
C0079399 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Subject Diary Completion
Item
complete the daily diaries for at least 70% of the days of the study
boolean
C3890583 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
Analgesic Pain Reliever Dose Stable | Analgesic Pain Reliever Non-Prescription Dose Stable
Item
participants may continue other prescription and nonprescription analgesic pain medications as long as the dose has been stable for 1 month prior to study entry, and they agree to maintain that stable dose throughout the study disease diagnostic criteria:
boolean
C0939253 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0939253 (UMLS CUI [2,1])
C0013231 (UMLS CUI [2,2])
C0178602 (UMLS CUI [2,3])
C0205360 (UMLS CUI [2,4])
Multiple Sclerosis
Item
diagnosis of ms at least 1 year prior to study entry
boolean
C0026769 (UMLS CUI [1])
Multiple sclerosis relapse Absent | Therapy change Absent
Item
no ms flares or change in disease treatment for the 3 months prior to study entry
boolean
C0856120 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C3665894 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Pain daily Due to Multiple Sclerosis | Pain daily Duration
Item
daily pain due to ms for a minimum of 3 months prior to study entry
boolean
C3845611 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
C3845611 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
Study Subject Participation Status | Multiple Sclerosis Modification Therapy
Item
are currently in a clinical trial of ms disease-modifying therapy
boolean
C2348568 (UMLS CUI [1])
C0026769 (UMLS CUI [2,1])
C0392747 (UMLS CUI [2,2])
C0087111 (UMLS CUI [2,3])
Pain | Cause Determination Difficult | Exception Multiple Sclerosis
Item
have pain that cannot be clearly differentiated from causes other than ms
boolean
C0030193 (UMLS CUI [1])
C0015127 (UMLS CUI [2,1])
C1148554 (UMLS CUI [2,2])
C0332218 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0026769 (UMLS CUI [3,2])
Manic Disorder | Bipolar Disorder | Psychotic Disorders | Schizoaffective Disorder
Item
any current or historical diagnosis of mania, bipolar disorder, psychosis, or schizoaffective disorder
boolean
C0024713 (UMLS CUI [1])
C0005586 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C0036337 (UMLS CUI [4])
Substance Use Disorders | Substance Dependence
Item
history of substance abuse or dependence
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
are pregnant or breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])