Multiple Myeloma
Item
meet established criteria for the diagnosis of multiple myeloma
boolean
C0026764 (UMLS CUI [1])
Disease Durie/Salmon Stage
Item
durie-salmon stage ii or iii disease
boolean
C0012634 (UMLS CUI [1,1])
C4528204 (UMLS CUI [1,2])
Measurable Disease Serum | Measurable Disease In Urine
Item
measurable disease in the serum and/or urine
boolean
C1513041 (UMLS CUI [1,1])
C0229671 (UMLS CUI [1,2])
C1513041 (UMLS CUI [2,1])
C0042037 (UMLS CUI [2,2])
High-dose chemotherapy Scheduled Multiple Myeloma | Autologous hematopoietic stem cell transplant Scheduled Multiple Myeloma
Item
scheduled to receive high dose chemotherapy and autologous stem cell transplant for multiple myeloma
boolean
C1328050 (UMLS CUI [1,1])
C0205539 (UMLS CUI [1,2])
C0026764 (UMLS CUI [1,3])
C2193200 (UMLS CUI [2,1])
C0205539 (UMLS CUI [2,2])
C0026764 (UMLS CUI [2,3])
Elapsed Time Since Autologous hematopoietic stem cell transplant
Item
individuals who have previously undergone autologous stem cell transplant are eligible for this study provided more than 6 months have elapsed from the prior transplant.
boolean
C2826303 (UMLS CUI [1,1])
C1711239 (UMLS CUI [1,2])
C2193200 (UMLS CUI [1,3])
Stem cells Dose CD34 positive | Stem cells Storage Minimum Autologous Stem Cell Rescue
Item
minimum stem cell dose of 4x106 cd34+ mnc / kg stored for autologous stem cell rescue.
boolean
C0038250 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0882849 (UMLS CUI [1,3])
C0038250 (UMLS CUI [2,1])
C1698986 (UMLS CUI [2,2])
C1524031 (UMLS CUI [2,3])
C2825926 (UMLS CUI [2,4])
Hematologic function | Absolute neutrophil count | Platelet Count measurement
Item
adequate hematologic reserve as evidenced by anc ≥ 1500/mm3 and platelets ≥
boolean
C0221130 (UMLS CUI [1])
C0948762 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
ID.8
Item
100,000/mm3.
boolean
Serum direct bilirubin measurement | Transaminase Assay
Item
serum direct bilirubin ≤ 2.0 mg/dl and transaminases ≤ 3x institution upper limit of normal.
boolean
C1883011 (UMLS CUI [1])
C0919834 (UMLS CUI [2])
Creatinine measurement, serum | Estimation of creatinine clearance by Cockcroft-Gault formula | Creatinine clearance measurement
Item
serum creatinine ≤ 2 mg/dl with creatinine clearance ≥ 60 ml/min (either calculated or measured).
boolean
C0201976 (UMLS CUI [1])
C2711451 (UMLS CUI [2])
C0373595 (UMLS CUI [3])
Multiple Myeloma Durie/Salmon Stage | Smoldering myeloma | Plasmacytoma Isolated | Monoclonal Gammopathy Benign
Item
stage i or smoldering myeloma, isolated plasmacytoma, or benign monoclonal gammopathy
boolean
C0026764 (UMLS CUI [1,1])
C4528204 (UMLS CUI [1,2])
C1531608 (UMLS CUI [2])
C0032131 (UMLS CUI [3,1])
C0205409 (UMLS CUI [3,2])
C1136085 (UMLS CUI [4,1])
C0205183 (UMLS CUI [4,2])
Non-secretory myeloma
Item
non-secretory multiple myeloma
boolean
C0456845 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Contraceptive methods Unwilling
Item
males and females who do not agree to practice approved methods of birth control for the duration of the study
boolean
C0700589 (UMLS CUI [1,1])
C0558080 (UMLS CUI [1,2])
Communicable Disease
Item
presence of active infection
boolean
C0009450 (UMLS CUI [1])
Prior radiation therapy Organ Critical | Kidney Greater Than cGy Quantity | Liver Greater Than cGy Quantity | Lung Greater Than cGy Quantity
Item
receipt of previous radiation therapy to critical organs exceeding any of the following limits: kidney 500 cgy, liver 1000 cgy, lungs 500 cgy
boolean
C0279134 (UMLS CUI [1,1])
C0178784 (UMLS CUI [1,2])
C1511545 (UMLS CUI [1,3])
C0022646 (UMLS CUI [2,1])
C0439093 (UMLS CUI [2,2])
C0556645 (UMLS CUI [2,3])
C1265611 (UMLS CUI [2,4])
C0023884 (UMLS CUI [3,1])
C0439093 (UMLS CUI [3,2])
C0556645 (UMLS CUI [3,3])
C1265611 (UMLS CUI [3,4])
C0024109 (UMLS CUI [4,1])
C0439093 (UMLS CUI [4,2])
C0556645 (UMLS CUI [4,3])
C1265611 (UMLS CUI [4,4])