Criteria Fulfill
Item
a subject must meet all of the following criteria to be eligible for the study. these will be evaluated within the four weeks prior to enrolment.
boolean
C0243161 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
Refractory multiple myeloma Primary | Recurrent multiple myeloma Primary
Item
subject must have primary refractory or relapsed multiple myeloma.
boolean
C0278620 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C1370446 (UMLS CUI [2,1])
C0205225 (UMLS CUI [2,2])
Serum Monoclonal gammopathy Measurable | Urine Monoclonal gammopathy Measurable
Item
subject must have a measurable serum or urine monoclonal gammopathy at the time of their latest relapse.
boolean
C0229671 (UMLS CUI [1,1])
C1136085 (UMLS CUI [1,2])
C1513040 (UMLS CUI [1,3])
C0042036 (UMLS CUI [2,1])
C1136085 (UMLS CUI [2,2])
C1513040 (UMLS CUI [2,3])
Transplantation of autologous hematopoietic stem cell Guidelines Fulfill | Renal function | Cardiac function | Pulmonary function | Liver function
Item
subject must meet institutional guidelines for autologous hsct with adequate renal, cardiac, pulmonary and hepatic function.
boolean
C1831743 (UMLS CUI [1,1])
C0162791 (UMLS CUI [1,2])
C1550543 (UMLS CUI [1,3])
C0232804 (UMLS CUI [2])
C0232164 (UMLS CUI [3])
C0231921 (UMLS CUI [4])
C0232741 (UMLS CUI [5])
Graft Hematopoietic stem cells Autologous CD34 positive
Item
an autologous hematopoietic stem cell graft containing more than 2.5 x 106 cd34+
boolean
C0332835 (UMLS CUI [1,1])
C0018956 (UMLS CUI [1,2])
C0439859 (UMLS CUI [1,3])
C0882849 (UMLS CUI [1,4])
Graft CD34 positive Amount Cryopreserved | Graft Available Transplantation
Item
cells/kg must be cryopreserved and available for transplantation.
boolean
C0332835 (UMLS CUI [1,1])
C0882849 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0010405 (UMLS CUI [1,4])
C0332835 (UMLS CUI [2,1])
C0470187 (UMLS CUI [2,2])
C0040732 (UMLS CUI [2,3])
Age
Item
subject must be of age more than 18 and less than 60 years.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
subject must have an ecog performance score of 0,1, or 2.
boolean
C1520224 (UMLS CUI [1])
Protocol Compliance
Item
subject must have the ability to comply with the protocol visit schedule and other protocol requirements.
boolean
C0525058 (UMLS CUI [1])
Criteria Fulfill
Item
a subject meeting any of the following criteria is not eligible for participation in the study:
boolean
C0243161 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
Non-secretory myeloma | Plasma Cell Disease | Exception Multiple Myeloma
Item
subject with non-secretory multiple myeloma or any plasma cell disorders other that mm.
boolean
C0456845 (UMLS CUI [1])
C0032112 (UMLS CUI [2,1])
C0012634 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0026764 (UMLS CUI [3,2])
Absence Prior Therapy Multiple Myeloma | Absence Adrenal Cortex Hormones intense
Item
subjects that have not received previous therapy with adequate intense corticosteroids for multiple myeloma.
boolean
C0332197 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
C0026764 (UMLS CUI [1,3])
C0332197 (UMLS CUI [2,1])
C0001617 (UMLS CUI [2,2])
C0522510 (UMLS CUI [2,3])
Life Expectancy Limited Severe | Etiology Comorbidity
Item
subjects with a severely limited life expectancy by concomitant illness, defined as a life-expectancy of less than 6 months.
boolean
C0023671 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C0015127 (UMLS CUI [2,1])
C0009488 (UMLS CUI [2,2])
Prior radiation therapy | Cancer Other
Item
subjects who have previously received radiation treatments or other neoplastic disorders.
boolean
C0279134 (UMLS CUI [1])
C1707251 (UMLS CUI [2])
Study Subject Participation Status | Compliance behavior Lacking
Item
subjects with a history of non-compliance in other studies.
boolean
C2348568 (UMLS CUI [1])
C1321605 (UMLS CUI [2,1])
C0332268 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnant or lactating female subjects.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])