Prior Therapy Multiple Myeloma
Item
subjects with previously treated multiple myeloma
boolean
C1514463 (UMLS CUI [1,1])
C0026764 (UMLS CUI [1,2])
Serum M Protein Level Measurable | M Protein In Urine Level 24 hour urine sample
Item
measurable levels of m-protein in serum >= 0.5 g/dl [5g/l]) or urine (>= 0.2 g excreted in a 24-hour collection sample)
boolean
C0229671 (UMLS CUI [1,1])
C0700271 (UMLS CUI [1,2])
C0441889 (UMLS CUI [1,3])
C1513040 (UMLS CUI [1,4])
C0700271 (UMLS CUI [2,1])
C0042037 (UMLS CUI [2,2])
C0441889 (UMLS CUI [2,3])
C0456209 (UMLS CUI [2,4])
ECOG performance status
Item
ecog performance status of 0 - 2
boolean
C1520224 (UMLS CUI [1])
Contraceptive methods Adherence
Item
willing to follow pregnancy precautions
boolean
C0700589 (UMLS CUI [1,1])
C1510802 (UMLS CUI [1,2])
Myocardial Infarction | Deep Vein Thrombosis | Pulmonary Embolism
Item
patients with acute an myocardial infarction (mi) within the past 6 months, or patients with a history of deep vein thrombosis (dvt) or pulmonary embolism (pe) within the past 3 years
boolean
C0027051 (UMLS CUI [1])
C0149871 (UMLS CUI [2])
C0034065 (UMLS CUI [3])
Tuberculosis | Keratitis, Herpetic | Systemic mycosis | Communicable Diseases
Item
patients with tuberculous diseases, herpes simplex keratitis, systemic mycosis or other active infectious diseases
boolean
C0041296 (UMLS CUI [1])
C0019357 (UMLS CUI [2])
C0553576 (UMLS CUI [3])
C0009450 (UMLS CUI [4])
Diabetic - poor control | Uncontrolled hypertension | Ulcer Digestive Uncontrolled | Glaucoma Uncontrolled
Item
patients with non-controlled diabetes, hypertension, digestive ulcer or glaucoma
boolean
C0421258 (UMLS CUI [1])
C1868885 (UMLS CUI [2])
C0041582 (UMLS CUI [3,1])
C0012238 (UMLS CUI [3,2])
C0205318 (UMLS CUI [3,3])
C0017601 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
Posterior subcapsular cataract
Item
patients with posterior subcapsular cataracts
boolean
C0858617 (UMLS CUI [1])
Mental disorders
Item
patients with mental illness
boolean
C0004936 (UMLS CUI [1])
Medical History Study Subject Participation Status Inappropriate | Complications Study Subject Participation Status Inappropriate
Item
patients with past histories or complications which make the investigator or other staff member deem them inappropriate for this study
boolean
C0262926 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1548788 (UMLS CUI [1,3])
C0009566 (UMLS CUI [2,1])
C2348568 (UMLS CUI [2,2])
C1548788 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
pregnant or lactating females
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Neuropathy CTCAE Grades
Item
grade 2 or worse neuropathy
boolean
C0442874 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Laboratory test result abnormal
Item
any of the following laboratory abnormalities:
boolean
C0438215 (UMLS CUI [1])
Absolute neutrophil count | Platelet Count measurement | Creatinine measurement, serum | Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
absolute neutrophil count (anc) < 1,000cells/ml platelet count < 75,000/ml serum creatinine > 2.5 mg/dl serum sgot/ast or sgpt/alt > 3.0 x upper limit of normal (uln)
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0201976 (UMLS CUI [3])
C0151904 (UMLS CUI [4])
C0151905 (UMLS CUI [5])
Malignant Neoplasms | Exception Multiple Myeloma | Exception Disease Free of | Therapeutic radiology procedure
Item
prior history of malignancies, other than multiple myeloma, unless the subject has been free of the disease for >= 3 years. - patients who received radiation therapy within 14 days of the start of study drug
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0026764 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0012634 (UMLS CUI [3,2])
C0332296 (UMLS CUI [3,3])
C1522449 (UMLS CUI [4])
Scars Due to Operative Surgical Procedures Viscera
Item
patients with scars from a recent viscus operation
boolean
C0241158 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0543467 (UMLS CUI [1,3])
C0042779 (UMLS CUI [1,4])
Rash desquamating | Blistering rash | Thalidomide
Item
patients with history of a desquamating (blistering) rash while taking thalidomide
boolean
C0542171 (UMLS CUI [1])
C0344311 (UMLS CUI [2])
C0039736 (UMLS CUI [3])
Lenalidomide
Item
patients with prior use of lenalidomide
boolean
C1144149 (UMLS CUI [1])
HIV Seropositivity
Item
patients with known hiv positivity.
boolean
C0019699 (UMLS CUI [1])
Cytotoxic Chemotherapy | Immunomodulators | Investigational New Drugs | Intent Treatment Multiple Myeloma
Item
patients who used cytotoxic chemotherapeutic agents, immunomodulating agents, or other experimental agents (agents that are not commercially available) intended for the treatment of mm within 28 days of the start of lenalidomide therapy.
boolean
C0677881 (UMLS CUI [1])
C1527392 (UMLS CUI [2])
C0013230 (UMLS CUI [3])
C1283828 (UMLS CUI [4,1])
C0087111 (UMLS CUI [4,2])
C0026764 (UMLS CUI [4,3])
Dexamethasone allergy
Item
patients with known history of hypersensitivity to dexamethasone.
boolean
C0571611 (UMLS CUI [1])