Ischaemic mitral regurgitation Severe chronic Transthoracic echocardiography | Effective Regurgitant Orifice Area | Echocardiography, Doppler, Color | Mitral Regurgitant Jet Area to Left Atrial Area Ratio | Vena contracta
Item
chronic severe ischemic mitral regurgitation (often with tethering as a major mechanism) in the judgment of the clinical site echocardiographer, assessed by transthoracic echocardiogram. assessment of mitral regurgitation will be performed using an integrative method (zoghbi w. et al. j. american society of echocardiography. 2003:16:777-802. see appendix). quantitative guidelines as proposed would be: ero ≥ 0.4 cmsq. if ero < 0.4, then the degree of mitral regurgitation will be guided by other color doppler quantitative methods (jet area/left atrial area ratio, vena contracta, supportive criteria in an integrated fashion
boolean
C4087284 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0205191 (UMLS CUI [1,3])
C0430462 (UMLS CUI [1,4])
C4264252 (UMLS CUI [2])
C0013521 (UMLS CUI [3])
C4288733 (UMLS CUI [4])
C2732913 (UMLS CUI [5])
Eligibility Mitral valvuloplasty | Eligibility Replacement of mitral valve
Item
eligible for surgical repair and replacement of mitral valve
boolean
C1548635 (UMLS CUI [1,1])
C0396849 (UMLS CUI [1,2])
C1548635 (UMLS CUI [2,1])
C0026268 (UMLS CUI [2,2])
Coronary Artery Disease | Patient need for Coronary revascularisation | Absence Need Coronary revascularisation
Item
cad with or without the need for coronary revascularization
boolean
C1956346 (UMLS CUI [1])
C0686904 (UMLS CUI [2,1])
C0877341 (UMLS CUI [2,2])
C0332197 (UMLS CUI [3,1])
C0027552 (UMLS CUI [3,2])
C0877341 (UMLS CUI [3,3])
Diseases of mitral valve structural | Diseases of mitral valve Chorda tendinea | Diseases of mitral valve Leaflet | Mitral papillary muscle rupture
Item
any evidence of structural (chordal or leaflet) mitral valve disease or ruptured papillary muscle
boolean
C0026265 (UMLS CUI [1,1])
C0678594 (UMLS CUI [1,2])
C0026265 (UMLS CUI [2,1])
C0008484 (UMLS CUI [2,2])
C0026265 (UMLS CUI [3,1])
C0447009 (UMLS CUI [3,2])
C0238414 (UMLS CUI [4])
Mitral valvuloplasty Previous
Item
prior mitral valve repair
boolean
C0396849 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
Pulmonary Hypertension Severe
Item
severe irreversible pulmonary hypertension in the judgment of the investigator
boolean
C0020542 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Cardiopulmonary Bypass Receive Unable
Item
medically unable to undergo cardiopulmonary bypass (cpb)
boolean
C0007202 (UMLS CUI [1,1])
C1514756 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Effective Regurgitant Orifice Area Transthoracic echocardiography Unsuccessful | Other Coding
Item
inability to derive ero and end-systolic volume index (esvi) by transthoracic echocardiography
boolean
C4264252 (UMLS CUI [1,1])
C0430462 (UMLS CUI [1,2])
C1272705 (UMLS CUI [1,3])
C3846158 (UMLS CUI [2])
Intraoperative procedures Planned | Exception Repair of tricuspid valve | Exception Closure of patent foramen ovale | Exception Atrioseptoplasty | Exception Surgical Maze Procedure
Item
planned concomitant intra-operative procedures (with the exception of tricuspid valve repair, closure of patent foramen ovale [pfo] or atrial septal defect [asd] or maze procedure)
boolean
C0243164 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0396899 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0189967 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0189965 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C3272262 (UMLS CUI [5,2])
Sign or Symptom Cardiogenic Shock
Item
clinical signs of cardiogenic shock at the time of surgery
boolean
C3540840 (UMLS CUI [1,1])
C0036980 (UMLS CUI [1,2])
Inotropic agent Intravenous Long-term
Item
treatment with long-term intravenous inotropic therapy at the time of surgery
boolean
C0304509 (UMLS CUI [1,1])
C1522726 (UMLS CUI [1,2])
C0443252 (UMLS CUI [1,3])
ST segment elevation myocardial infarction Requirement Intervention
Item
st segment elevation myocardial infarction (mi) requiring intervention in the 7 days before surgery
boolean
C1536220 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0184661 (UMLS CUI [1,3])
Congenital heart disease | Exception Patent Foramen Ovale | Exception Atrial Septal Defects
Item
congenital heart disease (except pfo or asd)
boolean
C0152021 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0016522 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0018817 (UMLS CUI [3,2])
Liver Cirrhosis | Liver synthetic function Failure
Item
evidence of cirrhosis or liver synthetic failure
boolean
C0023890 (UMLS CUI [1])
C4313898 (UMLS CUI [2,1])
C0231174 (UMLS CUI [2,2])
Risk Surgical Excessive
Item
excessive surgical risk, as judged by the surgical investigator
boolean
C0035647 (UMLS CUI [1,1])
C0543467 (UMLS CUI [1,2])
C0442802 (UMLS CUI [1,3])
Mental disorders Impairing Protocol Compliance | Substance Use Disorders
Item
recent history of psychiatric disease (including drug or alcohol abuse) that is likely to impair compliance with the study, as judged by the investigator
boolean
C0004936 (UMLS CUI [1,1])
C0221099 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C0038586 (UMLS CUI [2])
Intervention Investigational | Study Subject Participation Status | Intervention Investigational Additional
Item
therapy with an investigational intervention at the time of screening, or planning to enroll in an additional investigational intervention study during participation in this study
boolean
C0184661 (UMLS CUI [1,1])
C1517586 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])
C0184661 (UMLS CUI [3,1])
C1517586 (UMLS CUI [3,2])
C1524062 (UMLS CUI [3,3])
Comorbidity | Life Expectancy
Item
any concurrent disease with a life expectancy of less than 2 years
boolean
C0009488 (UMLS CUI [1])
C0023671 (UMLS CUI [2])
Pregnancy
Item
pregnant
boolean
C0032961 (UMLS CUI [1])