Mitral Valve Insufficiency Moderate Transthoracic echocardiography | Effective Regurgitant Orifice Area | Echocardiography, Doppler, Color | Mitral Regurgitant Jet Area to Left Atrial Area Ratio | Vena contracta
Item
moderate mitral regurgitation in the judgment of the clinical site echocardiographer, assessed by transthoracic echocardiogram. assessment of mitral regurgitation will be performed using an integrative method (zoghbi w. et al. j. american society of echocardiography. 2003:16:777-802. see appendix). quantitative guidelines as proposed would be: ero between 0.2 cmsq to 0.39 cmsq. if ero < 0.2, then the degree of mitral regurgitation will be guided by other color doppler quantitative methods (jet area/left atrial area ratio, vena contracta, supportive criteria in an integrated fashion
boolean
C0026266 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
C0430462 (UMLS CUI [1,3])
C4264252 (UMLS CUI [2])
C0013521 (UMLS CUI [3])
C4288733 (UMLS CUI [4])
C2732913 (UMLS CUI [5])
Coronary Artery Disease Amenable Coronary Artery Bypass Surgery | Indication Revascularization
Item
cad that is amenable to cabg and a clinical indication for revascularization
boolean
C1956346 (UMLS CUI [1,1])
C3900053 (UMLS CUI [1,2])
C0010055 (UMLS CUI [1,3])
C3146298 (UMLS CUI [2,1])
C0581603 (UMLS CUI [2,2])
Age
Item
age ≥ 18 years
boolean
C0001779 (UMLS CUI [1])
Diseases of mitral valve structural | Diseases of mitral valve Chorda tendinea | Diseases of mitral valve Leaflet
Item
any evidence of structural (chordal or leaflet) mitral valve disease
boolean
C0026265 (UMLS CUI [1,1])
C0678594 (UMLS CUI [1,2])
C0026265 (UMLS CUI [2,1])
C0008484 (UMLS CUI [2,2])
C0026265 (UMLS CUI [3,1])
C0447009 (UMLS CUI [3,2])
Effective Regurgitant Orifice Area Transthoracic echocardiography Unsuccessful | Other Coding
Item
inability to derive ero and end-systolic volume index (esvi) by transthoracic echocardiography
boolean
C4264252 (UMLS CUI [1,1])
C0430462 (UMLS CUI [1,2])
C1272705 (UMLS CUI [1,3])
C3846158 (UMLS CUI [2])
Intraoperative procedures Planned | Exception Closure of patent foramen ovale | Exception Atrioseptoplasty | Exception Surgical Maze Procedure | Exception Excision Left Atrial Appendage
Item
planned concomitant intra-operative procedures (with the exception of closure of patent foramen ovale [pfo] or atrial septal defect [asd]or maze procedure or left atrial appendage excision)
boolean
C0243164 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0189967 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0189965 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C3272262 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C0728940 (UMLS CUI [5,2])
C4284918 (UMLS CUI [5,3])
Mitral valvuloplasty | Percutaneous Mitral Valve Repair
Item
prior surgical or percutaneous mitral valve repair
boolean
C0396849 (UMLS CUI [1])
C3272248 (UMLS CUI [2])
Medical contraindication Cardiopulmonary Bypass
Item
contraindication to cardiopulmonary bypass (cpb)
boolean
C1301624 (UMLS CUI [1,1])
C0007202 (UMLS CUI [1,2])
Sign or Symptom Cardiogenic Shock
Item
clinical signs of cardiogenic shock at the time of surgery
boolean
C3540840 (UMLS CUI [1,1])
C0036980 (UMLS CUI [1,2])
Inotropic agent Intravenous chronic
Item
treatment with chronic intravenous inotropic therapy at the time of surgery
boolean
C0304509 (UMLS CUI [1,1])
C1522726 (UMLS CUI [1,2])
C0205191 (UMLS CUI [1,3])
Pulmonary Hypertension Severe
Item
severe, irreversible pulmonary hypertension in the judgment of the investigator
boolean
C0020542 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
ST segment elevation myocardial infarction Requirement Intervention
Item
st segment elevation myocardial infarction (mi) requiring intervention in the 7 days before surgery
boolean
C1536220 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0184661 (UMLS CUI [1,3])
Congenital heart disease | Exception Patent Foramen Ovale | Exception Atrial Septal Defects
Item
congenital heart disease (except pfo or asd)
boolean
C0152021 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0016522 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0018817 (UMLS CUI [3,2])
Liver Cirrhosis | Liver synthetic function Failure
Item
evidence of cirrhosis or liver synthetic failure
boolean
C0023890 (UMLS CUI [1])
C4313898 (UMLS CUI [2,1])
C0231174 (UMLS CUI [2,2])
Mental disorders Impairing Protocol Compliance | Substance Use Disorders
Item
recent history of psychiatric disease (including drug or alcohol abuse) that is likely to impair compliance with the study, in the judgment of the investigator
boolean
C0004936 (UMLS CUI [1,1])
C0221099 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C0038586 (UMLS CUI [2])
Intervention Investigational | Study Subject Participation Status | Intervention Investigational Additional
Item
therapy with an investigational intervention at the time of screening, or planning to enroll in an additional investigational intervention study during participation in the study
boolean
C0184661 (UMLS CUI [1,1])
C1517586 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])
C0184661 (UMLS CUI [3,1])
C1517586 (UMLS CUI [3,2])
C1524062 (UMLS CUI [3,3])
Comorbidity | Life Expectancy
Item
any concurrent disease with a life expectancy of less than 2 years
boolean
C0009488 (UMLS CUI [1])
C0023671 (UMLS CUI [2])
Pregnancy
Item
pregnancy at the time of randomization
boolean
C0032961 (UMLS CUI [1])