Malignant Head and Neck Neoplasm Adult | Squamous cell carcinoma TNM clinical staging | Squamous Cell Carcinoma in situ | Adjuvant therapy Additional | Adjuvant therapy Additional Absent | Disease Free of
Item
eligible subjects includes all adult hn cancer patients who have been previously diagnosed with stage 1-4 and in-situ squamous cell carcinoma within the past 36 months (mos); with or without further adjuvant therapy and have been determined to be disease free at the time of consent
boolean
C0278996 (UMLS CUI [1,1])
C0001675 (UMLS CUI [1,2])
C0007137 (UMLS CUI [2,1])
C3258246 (UMLS CUI [2,2])
C0334245 (UMLS CUI [3])
C0677850 (UMLS CUI [4,1])
C1524062 (UMLS CUI [4,2])
C0677850 (UMLS CUI [5,1])
C1524062 (UMLS CUI [5,2])
C0332197 (UMLS CUI [5,3])
C0012634 (UMLS CUI [6,1])
C0332296 (UMLS CUI [6,2])
Able to swallow food Orally | Able to swallow Oral medication
Item
patients must be able to take nutrition/medications orally
boolean
C0566359 (UMLS CUI [1,1])
C0442027 (UMLS CUI [1,2])
C2712086 (UMLS CUI [2,1])
C0175795 (UMLS CUI [2,2])
Absence Intolerance Berry | Absence Hypersensitivity Berry | Absence Intolerance Berry product | Absence Hypersensitivity Berry product
Item
have no prior history of intolerance or allergy to berry or berry-containing products
boolean
C0332197 (UMLS CUI [1,1])
C0231199 (UMLS CUI [1,2])
C0005135 (UMLS CUI [1,3])
C0332197 (UMLS CUI [2,1])
C0020517 (UMLS CUI [2,2])
C0005135 (UMLS CUI [2,3])
C0332197 (UMLS CUI [3,1])
C0231199 (UMLS CUI [3,2])
C0005135 (UMLS CUI [3,3])
C1514468 (UMLS CUI [3,4])
C0332197 (UMLS CUI [4,1])
C0020517 (UMLS CUI [4,2])
C0005135 (UMLS CUI [4,3])
C1514468 (UMLS CUI [4,4])
Cyclooxygenase Inhibitors chronic | Cyclooxygenase 1 inhibitors chronic | Cyclooxygenase 2 Inhibitors chronic | Indomethacin chronic | Ibuprofen chronic | Celebrex chronic | Herbal Supplements | Pharmaceutical Preparations Discontinue Unsuccessful | Pharmaceutical Preparations Dose Daily
Item
patients taking cyclooxygenase (cox)-1/cox-2 inhibitors (indomethacin, ibuprofen, celebrex) chronically, herbal supplements, who cannot be taken off the medication/supplement due to their clinical condition are eligible to participate in the study but should document daily doses of these medications in their logbooks
boolean
C0085387 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0389003 (UMLS CUI [2,1])
C0243077 (UMLS CUI [2,2])
C0205191 (UMLS CUI [2,3])
C1257954 (UMLS CUI [3,1])
C0205191 (UMLS CUI [3,2])
C0021246 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
C0020740 (UMLS CUI [5,1])
C0205191 (UMLS CUI [5,2])
C0719198 (UMLS CUI [6,1])
C0205191 (UMLS CUI [6,2])
C1504473 (UMLS CUI [7])
C0013227 (UMLS CUI [8,1])
C1444662 (UMLS CUI [8,2])
C1272705 (UMLS CUI [8,3])
C0013227 (UMLS CUI [9,1])
C0178602 (UMLS CUI [9,2])
C0332173 (UMLS CUI [9,3])
Intolerance Berry | Hypersensitivity Berry | Intolerance Berry product | Hypersensitivity Berry product
Item
history of intolerance (including hypersensitivity or allergy) to berry or berry-containing products
boolean
C0231199 (UMLS CUI [1,1])
C0005135 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0005135 (UMLS CUI [2,2])
C0231199 (UMLS CUI [3,1])
C0005135 (UMLS CUI [3,2])
C1514468 (UMLS CUI [3,3])
C0020517 (UMLS CUI [4,1])
C0005135 (UMLS CUI [4,2])
C1514468 (UMLS CUI [4,3])
Lacking Able to swallow food Orally | Lacking Able to swallow fluid Orally | Aspiration Pneumonia
Item
inability to take oral nutrition/liquids or history of aspiration pneumonia
boolean
C0332268 (UMLS CUI [1,1])
C0566359 (UMLS CUI [1,2])
C0442027 (UMLS CUI [1,3])
C0332268 (UMLS CUI [2,1])
C0566364 (UMLS CUI [2,2])
C0442027 (UMLS CUI [2,3])
C0032290 (UMLS CUI [3])
Pregnancy | Black raspberry Adverse effects Unknown | Lyophilized Black Raspberry Lozenge To be stopped
Item
pregnant women: although there are no known adverse effects of black raspberries upon the fetus, if patients become pregnant during period of lyophilized black raspberries (lbr) administration, then lbr will be discontinued and patient will be removed from the study; we should however emphasize, given this is a food based-study, that risks are likely extremely low even though a participant should become pregnant; as such, we are not recommending active contraception for women, but rather if participants become pregnant, that they notify their study doctor, and that they will likely be removed from study; there are no expected or logical risks if men were to father a child, and as such, no contraception will be recommended for men
boolean
C0032961 (UMLS CUI [1])
C1031004 (UMLS CUI [2,1])
C0879626 (UMLS CUI [2,2])
C0439673 (UMLS CUI [2,3])
C3274577 (UMLS CUI [3,1])
C1272691 (UMLS CUI [3,2])
Informed Consent Unable
Item
inability to grant informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Strict vegetarian
Item
strict vegetarians will be excluded from the study; it was found that consuming one portion per day of fruit or vegetables resulted in a significant decrease in oral cancer incidence; in those persons consuming multiple portions each day, there was a 50% reduction in risk; we assume that strict vegetarians will consume multiple portions each day of foods with chemopreventive activity and therefore inclusion of these individuals would have a negative impact on the study; there are several reports in the literature that herbal or multivitamin/mineral supplements have no effect on oral cancer incidence
boolean
C3241968 (UMLS CUI [1])