Squamous cell carcinoma of lung metastatic TNM clinical staging | Lung squamous cell carcinoma recurrent TNM clinical staging
Item
have histologically or cytologically confirmed metastatic stage iiib (pleural effusion; iva on revised iaslc staging) or stage iv, or recurrent squamous cell carcinoma of the lung.
boolean
C0149782 (UMLS CUI [1,1])
C1522484 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
C0854989 (UMLS CUI [2,1])
C3258246 (UMLS CUI [2,2])
Measurable Disease
Item
have measurable disease.
boolean
C1513041 (UMLS CUI [1])
Chemotherapy naive Squamous cell carcinoma of lung metastatic | Chemotherapy naive Lung squamous cell carcinoma recurrent | Exception Some
Item
be chemotherapy naïve for their metastatic or recurrent scclc, with some exceptions.
boolean
C0392920 (UMLS CUI [1,1])
C0919936 (UMLS CUI [1,2])
C0149782 (UMLS CUI [1,3])
C1522484 (UMLS CUI [1,4])
C0392920 (UMLS CUI [2,1])
C0919936 (UMLS CUI [2,2])
C0854989 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0205392 (UMLS CUI [3,2])
Toxicity due to radiotherapy Absent | Toxicity due to chemotherapy Absent | Absence Toxicity Due to Operative Surgical Procedures
Item
have no continuing acute toxic effects of any prior radiotherapy, chemotherapy, or surgical procedures.
boolean
C1302210 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1302255 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0332197 (UMLS CUI [3,1])
C0600688 (UMLS CUI [3,2])
C0678226 (UMLS CUI [3,3])
C0543467 (UMLS CUI [3,4])
ECOG performance status
Item
have an ecog performance score of ≤ 2.
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
have a life expectancy of at least 3 months.
boolean
C0023671 (UMLS CUI [1])
Absolute neutrophil count | Platelet Count measurement | Platelet Transfusion Absent | Hemoglobin measurement | Red Blood Cell Transfusion | Red Blood Cell Transfusion Absent | Creatinine measurement, serum | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
absolute neutrophil count (anc) ≥ 1.5 x 10^9; platelets ≥ 100 x10^9 (without platelet transfusion);hemoglobin ≥ 9.0 g/dl (with or without rbc transfusion); serum creatinine ≤ 1.5 x upper limit of normal (uln); bilirubin ≤ 1.5 x uln; ast/alt ≤ 2.5 x uln.
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0086818 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C0518015 (UMLS CUI [4])
C0086252 (UMLS CUI [5])
C0086252 (UMLS CUI [6,1])
C0332197 (UMLS CUI [6,2])
C0201976 (UMLS CUI [7])
C1278039 (UMLS CUI [8])
C0201899 (UMLS CUI [9])
C0201836 (UMLS CUI [10])
Childbearing Potential Pregnancy test negative
Item
negative pregnancy test for females with childbearing potential.
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Therapies, Investigational | Antineoplastic Agents Investigational
Item
receive concurrent therapy with any other investigational anticancer agent while on study.
boolean
C0949266 (UMLS CUI [1])
C0003392 (UMLS CUI [2,1])
C1517586 (UMLS CUI [2,2])
Metastatic malignant neoplasm to brain
Item
have a known past or current history of brain metastasis(es).
boolean
C0220650 (UMLS CUI [1])
Therapeutic immunosuppression | HIV Infection | Hepatitis B | Hepatitis C
Item
be on immunosuppressive therapy or have known hiv infection or active hepatitis b or c.
boolean
C0021079 (UMLS CUI [1])
C0019693 (UMLS CUI [2])
C0019163 (UMLS CUI [3])
C0019196 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
be a pregnant or breast-feeding woman.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Heart Disease
Item
have clinically significant cardiac disease.
boolean
C0018799 (UMLS CUI [1])
Dementia Preventing Informed Consent | Mental state altered Preventing Informed Consent
Item
have dementia or altered mental status that would prohibit informed consent.
boolean
C0497327 (UMLS CUI [1,1])
C1292733 (UMLS CUI [1,2])
C0021430 (UMLS CUI [1,3])
C0278060 (UMLS CUI [2,1])
C0392747 (UMLS CUI [2,2])
C1292733 (UMLS CUI [2,3])
C0021430 (UMLS CUI [2,4])
Medical condition Study Subject Participation Status At risk | Medical condition At risk Investigational New Drugs | Medical condition Interferes with Interpretation Research results | Medical condition Study Subject Participation Status Inappropriate | Mental condition Study Subject Participation Status At risk | Mental condition At risk Investigational New Drugs | Mental condition Interferes with Interpretation Research results | Mental condition Study Subject Participation Status Inappropriate | Laboratory test result abnormal Study Subject Participation Status At risk | Laboratory test result abnormal At risk Investigational New Drugs | Laboratory test result abnormal Interferes with Interpretation Research results | Laboratory test result abnormal Study Subject Participation Status Inappropriate
Item
have any other acute, or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or study drug administration or may interfere with the interpretation of study results and, in the judgment of the principal investigator, would make the patient inappropriate for this study.
boolean
C3843040 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1444641 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2,1])
C1444641 (UMLS CUI [2,2])
C0013230 (UMLS CUI [2,3])
C3843040 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0459471 (UMLS CUI [3,3])
C0683954 (UMLS CUI [3,4])
C3843040 (UMLS CUI [4,1])
C2348568 (UMLS CUI [4,2])
C1548788 (UMLS CUI [4,3])
C3840291 (UMLS CUI [5,1])
C2348568 (UMLS CUI [5,2])
C1444641 (UMLS CUI [5,3])
C3840291 (UMLS CUI [6,1])
C1444641 (UMLS CUI [6,2])
C0013230 (UMLS CUI [6,3])
C3840291 (UMLS CUI [7,1])
C0521102 (UMLS CUI [7,2])
C0459471 (UMLS CUI [7,3])
C0683954 (UMLS CUI [7,4])
C3840291 (UMLS CUI [8,1])
C2348568 (UMLS CUI [8,2])
C1548788 (UMLS CUI [8,3])
C0438215 (UMLS CUI [9,1])
C2348568 (UMLS CUI [9,2])
C1444641 (UMLS CUI [9,3])
C0438215 (UMLS CUI [10,1])
C1444641 (UMLS CUI [10,2])
C0013230 (UMLS CUI [10,3])
C0438215 (UMLS CUI [11,1])
C0521102 (UMLS CUI [11,2])
C0459471 (UMLS CUI [11,3])
C0683954 (UMLS CUI [11,4])
C0438215 (UMLS CUI [12,1])
C2348568 (UMLS CUI [12,2])
C1548788 (UMLS CUI [12,3])