Major Depressive Disorder, DSM-IV, Axis I diagnosis, Hamilton rating scale for depression
Item
currently in an episode of nonpsychotic major depression, as defined by the dsm-iv and documented by both the structured clinical interview for axis i, dsm-iv disorders (scid) and by a rating of greater than 15 on the 25-item hamilton rating scale for depression (hrsd)
boolean
C1269683 (UMLS CUI [1,1])
C0220952 (UMLS CUI [1,2])
C0270287 (UMLS CUI [1,3])
C0451203 (UMLS CUI [1,4])
Panic disorder
Item
panic spectrum risk category of at least 7, as defined by the panic-agoraphobic spectrum self-report (pas-sr), last month version
boolean
C0030319 (UMLS CUI [1])
Antidepressive Agents, Effectiveness, No
Item
not currently receiving effective treatment
boolean
C0003289 (UMLS CUI [1,1])
C1280519 (UMLS CUI [1,2])
C1298908 (UMLS CUI [1,3])
Suicidal, Outpatient procedure, Effective
Item
participants with suicidal ideation are eligible as long as outpatient treatment is deemed safe.
boolean
C0438696 (UMLS CUI [1,1])
C1299353 (UMLS CUI [1,2])
C1704419 (UMLS CUI [1,3])
Manic episode, Previous; hypomanic episode, Previous
Item
history of manic or hypomanic episode(s)
boolean
C0349208 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C1396834 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
Schizophrenia, Previous; Schizoaffective Disorder, Previous
Item
history of schizophrenia or schizoaffective disorder
boolean
C0036341 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0036337 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
Mood Disorders Due to Disease; Mood Disorders Due to Substance Use Disorders
Item
mood disorder due to a general medical condition or induced by substance use
boolean
C0525045 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0012634 (UMLS CUI [1,3])
C0525045 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0038586 (UMLS CUI [2,3])
Psychotic Disorders, Present
Item
presence of psychosis
boolean
C0033975 (UMLS CUI [1,1])
C0150312 (UMLS CUI [1,2])
Pregnancy; Pregnancy, Planned
Item
current pregnancy or plans to become pregnant
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Anorexia Nervosa, primary disorders, current; Bulimia Nervosa, primary disorders, current
Item
of anorexia nervosa or bulimia nervosa (this does not include an eating disorder not otherwise specified [nos])
boolean
C0003125 (UMLS CUI [1,1])
C0277554 (UMLS CUI [1,2])
C0521116 (UMLS CUI [1,3])
C2267227 (UMLS CUI [2,1])
C0277554 (UMLS CUI [2,2])
C0521116 (UMLS CUI [2,3])
Obsessive-Compulsive Disorder, Severe, primary disorders, Current
Item
current primary diagnosis of severe obsessive-compulsive disorder (ocd), as determined by clinician evaluation of symptom severity and temporal onset of symptoms
boolean
C0028768 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0277554 (UMLS CUI [1,3])
C0521116 (UMLS CUI [1,4])
Substance Use Disorders, Previous; Substance Dependence, Previous
Item
drug or alcohol abuse or dependence within the past 3 months (participants with episodic abuse related to mood episodes will not be excluded)
boolean
C0038586 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0038580 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
Antisocial Personality Disorder, DSM-IV
Item
satisfies full dsm-iv criteria for antisocial personality disorder, as determined by scid-ii evaluation
boolean
C0003431 (UMLS CUI [1,1])
C0220952 (UMLS CUI [1,2])
Suicidal,Therapeutic procedure, inpatient; Psychotic symptom, Therapeutic procedure, inpatient
Item
requires inpatient treatment because of suicidal risk or (current suicidal thinking or parasuicidal behavior is not exclusionary if, in clinician judgment, it can be managed on an outpatient basis)
boolean
C0438696 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0021562 (UMLS CUI [1,3])
C0871189 (UMLS CUI [2,1])
C0087111 (UMLS CUI [2,2])
C0021562 (UMLS CUI [2,3])
ID.15
Item
any of the following medical conditions:
boolean
Depressive episode Due to Prescribed medications
Item
1. an index episode that is secondary to the effect of medically prescribed drugs, i.e., reserpine, antihistamines, etc.
boolean
C0349217 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C3166216 (UMLS CUI [1,3])
Illness (finding), Significant, Uncontrolled, Present
Item
2. presence of significant uncontrolled medical illness including cardiovascular disorder, kidney or liver disease, epilepsy, untreated hypertension, or unstabilized endocrine disease (stable medical conditions such as well-controlled diabetes or hiv positive status are not exclusionary provided the participant meets other inclusion and exclusion criteria)
boolean
C0221423 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0205318 (UMLS CUI [1,3])
C0150312 (UMLS CUI [1,4])
Depressive disorder, Current Therapy, Pharmacotherapy; Depressive disorder, Current Therapy,Over The Counter Pharmaceutical Preparations; Depressive disorder, Current Therapy, Herbal Drugs; Anxiety, Current Therapy, Pharmacotherapy; Anxiety, Current Therapy, Over The Counter Pharmaceutical Preparations; Anxiety, Current Therapy, Herbal Drugs
Item
3. current treatment with a pharmacologic, over-the-counter, or herbal therapy for depression or anxiety (unless the participant wishes to discontinue an ineffective treatment)
boolean
C0011581 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
C0013216 (UMLS CUI [1,3])
C0011581 (UMLS CUI [2,1])
C2827774 (UMLS CUI [2,2])
C2709201 (UMLS CUI [2,3])
C0013227 (UMLS CUI [2,4])
C0011581 (UMLS CUI [3,1])
C2827774 (UMLS CUI [3,2])
C1360419 (UMLS CUI [3,3])
C0003467 (UMLS CUI [4,1])
C2827774 (UMLS CUI [4,2])
C0013216 (UMLS CUI [4,3])
C0003467 (UMLS CUI [5,1])
C2827774 (UMLS CUI [5,2])
C2709201 (UMLS CUI [5,3])
C0013227 (UMLS CUI [5,4])
C0003467 (UMLS CUI [6,1])
C2827774 (UMLS CUI [6,2])
C1360419 (UMLS CUI [6,3])
Poor response to treatment, Citalopram, Previous
Item
history of poor or failed treatment response to an adequate dose and duration of citalopram
boolean
C1320680 (UMLS CUI [1,1])
C0008845 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,3])