Major Depressive Disorder | Depression in children Rating scale | Hamilton depression rating scale (HDRS) | Depressive episode Duration
Item
diagnosed with mdd by a child and adolescent psychiatrist based on the dsm-iv, have a cdrs score of at least 60 or an hdrs score of at least 22 and have been suffering with depression during the current episode for at least 3 months
boolean
C1269683 (UMLS CUI [1])
C3826462 (UMLS CUI [2,1])
C0681889 (UMLS CUI [2,2])
C2021166 (UMLS CUI [3])
C0349217 (UMLS CUI [4,1])
C0449238 (UMLS CUI [4,2])
Patient Visit Psychiatrist
Item
currently seeing a johns hopkins psychiatrist
boolean
C1512346 (UMLS CUI [1,1])
C0033872 (UMLS CUI [1,2])
Unresponsive to Treatment
Item
excellent documentation of treatment resistance:
boolean
C0205269 (UMLS CUI [1])
Unresponsive to Antidepressant therapy Quantity | Antidepressive Agents Dose | Depressive episode | Intolerance to Antidepressive Agents Quantity
Item
to at least 2 different antidepressant treatments, defined as resistance to a minimum of two antidepressant drug trials of adequate dose and duration in the current episode or previous episodes, adequacy being defined as a minimum level of three on the athf per antidepressant drug trial (those who have not completed antidepressant trials of adequate dose and duration due to intolerance to therapy may be included if they have demonstrated intolerance to three or more antidepressant medications in the current or a previous episode)
boolean
C0205269 (UMLS CUI [1,1])
C1096649 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0003289 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0349217 (UMLS CUI [3])
C1744706 (UMLS CUI [4,1])
C0003289 (UMLS CUI [4,2])
C1265611 (UMLS CUI [4,3])
Unresponsive to Psychotherapy Course Quantity | Depressive Symptoms Relief Absent
Item
to at least one course of psychotherapy which did not result in significant alleviation of depressive symptoms
boolean
C0205269 (UMLS CUI [1,1])
C0033968 (UMLS CUI [1,2])
C0750729 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
C0086132 (UMLS CUI [2,1])
C0564405 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Medication dose unchanged | Psychotherapy Frequency unchanged
Item
no changes in medication dose or psychotherapy frequency over the previous 1 month
boolean
C3174092 (UMLS CUI [1,1])
C0442739 (UMLS CUI [1,2])
C0033968 (UMLS CUI [2,1])
C0439603 (UMLS CUI [2,2])
C0442739 (UMLS CUI [2,3])
Answer Negative | Safety Questionnaire rTMS
Item
negative answers on the safety screening questionnaire for rtms
boolean
C1706817 (UMLS CUI [1,1])
C1513916 (UMLS CUI [1,2])
C0036043 (UMLS CUI [2,1])
C0034394 (UMLS CUI [2,2])
C0872259 (UMLS CUI [2,3])
Substance Use Disorders | Substance Dependence | Exception Nicotine abuse | Exception Nicotine Dependence | Exception Caffeine abuse | Exception Caffeine dependence | Conduct Disorder Marked | Oppositional behavior
Item
history of substance abuse or dependence within the past six months (excluding nicotine and caffeine) or marked conduct disordered or oppositional behavior
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C2363943 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0028043 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C1404070 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C1386553 (UMLS CUI [6,2])
C0149654 (UMLS CUI [7,1])
C1706089 (UMLS CUI [7,2])
C2013199 (UMLS CUI [8])
Illness Unstable | Illness Surgical
Item
any current unstable medical or surgical illness
boolean
C0221423 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0221423 (UMLS CUI [2,1])
C0038895 (UMLS CUI [2,2])
Bipolar Disorder
Item
bipolar disorder
boolean
C0005586 (UMLS CUI [1])
Psychotic symptom
Item
psychotic symptoms
boolean
C0871189 (UMLS CUI [1])
Craniocerebral Trauma | Seizure | Seizure First Degree Relative
Item
history of head injury or seizure or history of seizure in a first degree relative.
boolean
C0018674 (UMLS CUI [1])
C0036572 (UMLS CUI [2])
C0036572 (UMLS CUI [3,1])
C1517194 (UMLS CUI [3,2])
Metal foreign body in head Outside Mouth
Item
history of any metal in the head (outside the mouth).
boolean
C0561024 (UMLS CUI [1,1])
C0205101 (UMLS CUI [1,2])
C0230028 (UMLS CUI [1,3])
Particles Metallic Eye | Pacemaker, Cardiac, Implantable | Lines Intracardiac | Implantable Neurostimulators | Surgical Clips | Pump
Item
known history of any metallic particles in the eye, implanted cardiac pacemaker or any intracardiac lines, implanted neurostimulators, surgical clips or any medical pumps
boolean
C0597177 (UMLS CUI [1,1])
C2986473 (UMLS CUI [1,2])
C0015392 (UMLS CUI [1,3])
C0182148 (UMLS CUI [2])
C0700221 (UMLS CUI [3,1])
C0729936 (UMLS CUI [3,2])
C2048402 (UMLS CUI [4])
C0038917 (UMLS CUI [5])
C0182537 (UMLS CUI [6])
Frequent or severe headaches | Migraines Frequent | Migraines Severe
Item
history of frequent or severe headaches or migraines
boolean
C3842524 (UMLS CUI [1])
C0149931 (UMLS CUI [2,1])
C0332183 (UMLS CUI [2,2])
C0149931 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
Hearing Loss | Cochlear Implants
Item
history of hearing loss or known history of cochlear implants.
boolean
C3887873 (UMLS CUI [1])
C0009199 (UMLS CUI [2])
Pregnancy | Contraceptive methods Absent
Item
pregnancy or not using a reliable method of birth control.
boolean
C0032961 (UMLS CUI [1])
C0700589 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Study Subject Participation Status
Item
participation in another clinical trial within 30 days of this study
boolean
C2348568 (UMLS CUI [1])
Motor Threshold Determination Unable | Motor Threshold Quantification Unable | rTMS Protocol
Item
inability to locate and quantify a motor threshold (mt) as defined by the rtms protocol
boolean
C0501384 (UMLS CUI [1,1])
C0449864 (UMLS CUI [1,2])
C1148554 (UMLS CUI [1,3])
C1299582 (UMLS CUI [1,4])
C0501384 (UMLS CUI [2,1])
C0449864 (UMLS CUI [2,2])
C1709793 (UMLS CUI [2,3])
C1299582 (UMLS CUI [2,4])
C0872259 (UMLS CUI [3,1])
C2348563 (UMLS CUI [3,2])
Pharmaceutical Preparations Causing Lowered convulsive threshold | Stimulant | Wellbutrin | Bupropion | Tricyclic Antidepressive Agents | Clomipramine | Maprotiline
Item
current use of drugs known to lower seizure threshold, such as stimulants, wellbutrin, bupropion, and certain tricyclics (e.g. clomipramine and maprotiline)
boolean
C0013227 (UMLS CUI [1,1])
C0678227 (UMLS CUI [1,2])
C0234976 (UMLS CUI [1,3])
C0304402 (UMLS CUI [2])
C0085934 (UMLS CUI [3])
C0085208 (UMLS CUI [4])
C0003290 (UMLS CUI [5])
C0009010 (UMLS CUI [6])
C0024778 (UMLS CUI [7])
Handedness
Item
left-handed
boolean
C0023114 (UMLS CUI [1])