Perimenopausal state | Postmenopausal state | Age
Item
peri-/postmenopausal women, aged 40-60 year
boolean
C3839366 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Moderate major depressive episode | Major depressive disorder, Single episode, Severe
Item
moderate to severe major depressive episode
boolean
C0154404 (UMLS CUI [1])
C4237172 (UMLS CUI [2])
Axis I diagnosis | Exception Major Depressive Disorder
Item
dsm-iv axis i diagnosis other than mdd
boolean
C0270287 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1269683 (UMLS CUI [2,2])
Medical contraindication Magnetic Resonance Imaging
Item
contraindications to magnetic resonance imaging
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
Unresponsive to Treatment
Item
treatment-resistent
boolean
C0205269 (UMLS CUI [1])
Prior Therapy failed | Duloxetine
Item
previous failed treatment with duloxetine
boolean
C1514463 (UMLS CUI [1,1])
C0231175 (UMLS CUI [1,2])
C0245561 (UMLS CUI [2])
Substance Use Disorders | Substance Dependence
Item
history of substance abuse or dependence in past year
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
At risk for suicide Serious
Item
serious suicidal risk
boolean
C0563664 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
Psychotropic Drugs
Item
use of other psychotropic medications
boolean
C0033978 (UMLS CUI [1])
Electroconvulsive Therapy | Transcranial magnetic stimulation
Item
electroconvulsive therapy or transmagnetic stimulation in past year
boolean
C0013806 (UMLS CUI [1])
C0436548 (UMLS CUI [2])
Allergic Reaction Duloxetine
Item
history of allergic reactions to duloxetine
boolean
C1527304 (UMLS CUI [1,1])
C0245561 (UMLS CUI [1,2])
Laboratory test result abnormal
Item
significant laboratory abnormalities at baseline
boolean
C0438215 (UMLS CUI [1])
Hepatic impairment Severe
Item
severe hepatic impairment
boolean
C0948807 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Kidney Failure, Chronic | Dialysis
Item
end stage renal disease and undergoing dialysis
boolean
C0022661 (UMLS CUI [1])
C0011946 (UMLS CUI [2])
Angle Closure Glaucoma Uncontrolled
Item
uncontrolled narrow-angle glaucoma
boolean
C0017605 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Hyperthyroidism Uncontrolled | Hypothyroidism Uncontrolled | Hyperthyroidism untreated | Hypothyroidism (if untreated) | Serum TSH level abnormal
Item
uncontrolled or untreated hyper-/hypothyroidism, or abnormal thyroid stimulating hormone concentration
boolean
C0020550 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0020676 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0020550 (UMLS CUI [3,1])
C0332155 (UMLS CUI [3,2])
C2749407 (UMLS CUI [4])
C0580434 (UMLS CUI [5])