Informed Consent
Item
written informed consent (signed and dated).
boolean
C0021430 (UMLS CUI [1])
Age
Item
age equal or greater than 18 at the time of consent.
boolean
C0001779 (UMLS CUI [1])
Follicular Lymphoma Ann Arbor lymphoma staging system
Item
histologically confirmed follicular nhl according to the revised european american lymphoma (real)/ world health organization (who) classification (from initial diagnosis) grades 1,2, or 3a.
boolean
C0024301 (UMLS CUI [1,1])
C0432516 (UMLS CUI [1,2])
Lymph nodes Malignant Size Quantity | Site of access Suitable Excision biopsy
Item
at least 2 malignant lymph nodes of similar size (>1 cm in minimal dimension) and location that are readily accessible for excisional biopsy at the time of study entry.
boolean
C0024204 (UMLS CUI [1,1])
C0205282 (UMLS CUI [1,2])
C0456389 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
C0589360 (UMLS CUI [2,1])
C3900053 (UMLS CUI [2,2])
C0184921 (UMLS CUI [2,3])
Consent Tumor Excision biopsy | Excision biopsy pre treatment Quantity | Excision biopsy post treatment Quantity
Item
consent to 1 pretreatment and 1 post-treatment excisional biopsy of accessible tumor.
boolean
C1511481 (UMLS CUI [1,1])
C0027651 (UMLS CUI [1,2])
C0184921 (UMLS CUI [1,3])
C0184921 (UMLS CUI [2,1])
C2709094 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0184921 (UMLS CUI [3,1])
C2709088 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
Hematologic function | Liver function | Renal function
Item
acceptable hematologic, hepatic, and renal function parameters.
boolean
C0221130 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
WHO performance status scale
Item
who performance status equal or less than 2.
boolean
C1298650 (UMLS CUI [1])
Females & males of reproductive potential Contraceptive methods
Item
subjects of reproductive potential must agree to follow accepted birth control methods.
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Central nervous system lymphoma
Item
presence of lymphoma in cns.
boolean
C0742472 (UMLS CUI [1])
Cancer treatment Systemic NHL | Therapeutic radiology procedure | Myeloablative Chemotherapy | Therapy, Investigational
Item
previous systemic anticancer treatment for nhl (including but not limited to radiation, myeloablative, or investigational therapy).
boolean
C0920425 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,3])
C1522449 (UMLS CUI [2])
C1513784 (UMLS CUI [3])
C0949266 (UMLS CUI [4])
Systemic steroids
Item
concurrent treatment with systemic steroids within 14 days of day 1.
boolean
C2825233 (UMLS CUI [1])
Lymphoma Transformed
Item
evidence of transformed lymphoma.
boolean
C0024299 (UMLS CUI [1,1])
C0457344 (UMLS CUI [1,2])
Malignant Neoplasms | Exception Carcinoma in situ of uterine cervix Treated | Exception DCIS Treated | Exception Basal cell carcinoma Treated | Exception Squamous cell carcinoma of skin Treated
Item
presence of malignancies within 3 years of study day 1 (except for adequately treated carcinoma in situ of the cervix, ductal carcinoma in situ (dcis) of breast, or basal or squamous cell skin cancer).
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0851140 (UMLS CUI [2,2])
C1522326 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0007124 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0007117 (UMLS CUI [4,2])
C1522326 (UMLS CUI [4,3])
C1705847 (UMLS CUI [5,1])
C0553723 (UMLS CUI [5,2])
C1522326 (UMLS CUI [5,3])
HIV Infection | Acquired Immunodeficiency Syndrome
Item
history of hiv infection or aids.
boolean
C0019693 (UMLS CUI [1])
C0001175 (UMLS CUI [2])
Disease Serious | Exception Malignant Neoplasms
Item
serious nonmalignant disease.
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0006826 (UMLS CUI [2,2])
Pregnancy
Item
pregnant.
boolean
C0032961 (UMLS CUI [1])
Protocol Compliance Unable
Item
inability to comply with study and follow-up procedures.
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Disease Contraindicated Investigational New Drugs | Dysfunction Metabolic Contraindicated Investigational New Drugs | Physical Examination Contraindicated Investigational New Drugs | Laboratory Results Contraindicated Investigational New Drugs
Item
any other disease, metabolic dysfunction, physical examination finding, or clinical laboratory finding that contraindicates the use of an investigational drug.
boolean
C0012634 (UMLS CUI [1,1])
C1444657 (UMLS CUI [1,2])
C0013230 (UMLS CUI [1,3])
C3887504 (UMLS CUI [2,1])
C0311400 (UMLS CUI [2,2])
C1444657 (UMLS CUI [2,3])
C0013230 (UMLS CUI [2,4])
C0031809 (UMLS CUI [3,1])
C1444657 (UMLS CUI [3,2])
C0013230 (UMLS CUI [3,3])
C1254595 (UMLS CUI [4,1])
C1444657 (UMLS CUI [4,2])
C0013230 (UMLS CUI [4,3])