Diffuse Large B-Cell Lymphoma CD20 positive WHO tumor classification
Item
histologically confirmed, cd20+, diffuse large b-cell lymphoma (dlbcl) according to who lymphoma classification
boolean
C0079744 (UMLS CUI [1,1])
C0882818 (UMLS CUI [1,2])
C1301142 (UMLS CUI [1,3])
Indolent Lymphoma Transformation
Item
histological transformation of a previously known indolent lymphoma allowed
boolean
C1334170 (UMLS CUI [1,1])
C1536010 (UMLS CUI [1,2])
Diffuse Large B-Cell Lymphoma Origin Indolent Lymphoma
Item
biopsy-proven dlbcl arising from an indolent lymphoma not diagnosed previously allowed
boolean
C0079744 (UMLS CUI [1,1])
C0439659 (UMLS CUI [1,2])
C1334170 (UMLS CUI [1,3])
First Relapse Post Complete remission | Partial response | Less Than Partial response Post First line treatment
Item
disease in first relapse after complete remission, partial response (pr), or less than a pr after first-line of treatment
boolean
C4054953 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C0677874 (UMLS CUI [1,3])
C1521726 (UMLS CUI [2])
C0439092 (UMLS CUI [3,1])
C1521726 (UMLS CUI [3,2])
C0687676 (UMLS CUI [3,3])
C1708063 (UMLS CUI [3,4])
Primary central nervous system lymphoma Absent
Item
no primary cns lymphoma
boolean
C0280803 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-2
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy > 3 months
boolean
C0023671 (UMLS CUI [1])
Creatinine measurement, serum
Item
serum creatinine < 150 μmol/l
boolean
C0201976 (UMLS CUI [1])
Serum total bilirubin measurement
Item
serum bilirubin < 35 μmol/l
boolean
C1278039 (UMLS CUI [1])
Transaminase Assay | Exception Relationship Lymphoma
Item
transaminases < 2.5 times upper limit of normal (unless attributed to lymphoma)
boolean
C0919834 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0439849 (UMLS CUI [2,2])
C0024299 (UMLS CUI [2,3])
Pregnancy Absent | Breast Feeding Absent
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Pregnancy test negative
Item
negative pregnancy test
boolean
C0427780 (UMLS CUI [1])
Fertility Contraceptive methods
Item
fertile patients must use effective contraception
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Exclusion | Medical contraindication Pharmaceutical Preparations Immunochemotherapy
Item
no contraindication to any of the drugs contained in the immunochemotherapy regimen
boolean
C2828389 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C4087148 (UMLS CUI [2,3])
Exclusion Cancer Other | Exception Basal cell carcinoma | Exception Squamous cell carcinoma of skin | Exception Carcinoma in situ of uterine cervix
Item
no other malignancy within the past 2 years, except basal cell or squamous cell carcinoma of the skin or carcinoma in situ of the cervix
boolean
C2828389 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0553723 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])
Exclusion | Disease Serious Preventing Chemotherapy
Item
no other serious active disease that, in the opinion of the investigator, would preclude the patient from having conventional chemotherapy
boolean
C2828389 (UMLS CUI [1])
C0012634 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C1292733 (UMLS CUI [2,3])
C0392920 (UMLS CUI [2,4])
Exclusion HIV Seropositivity
Item
no hiv positivity
boolean
C2828389 (UMLS CUI [1,1])
C0019699 (UMLS CUI [1,2])
Exclusion Criteria | Medical condition compromises Informed Consent | Mental condition compromises Informed Consent
Item
no medical or psychiatric conditions that compromise the patient's ability to give informed consent
boolean
C0680251 (UMLS CUI [1])
C3843040 (UMLS CUI [2,1])
C2945640 (UMLS CUI [2,2])
C0021430 (UMLS CUI [2,3])
C3840291 (UMLS CUI [3,1])
C2945640 (UMLS CUI [3,2])
C0021430 (UMLS CUI [3,3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
Unspecified
Item
not specified
boolean
C0205370 (UMLS CUI [1])