Age
Item
age: less than or equal to 18 years of age. may be greater than 18 years of age if currently a st. jude patient.
boolean
C0001779 (UMLS CUI [1])
Acute lymphocytic leukemia Recurrent | Acute lymphocytic leukemia refractory | Ineligibility Hemopoietic stem cell transplant | Absence Leukemia Remission | Blasts Bone marrow Percentage Morphology | Blasts Bone marrow Percentage Flow Cytometry
Item
patients with relapsed or refractory b-lineage all who are not eligible for hematopoietic stem cell transplantation (hsct) because their leukemia is not in remission (>5% blasts in bone marrow as evidenced either by morphology or by flow cytometry).
boolean
C0023449 (UMLS CUI [1,1])
C0277556 (UMLS CUI [1,2])
C0023449 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
C1512714 (UMLS CUI [3,1])
C0472699 (UMLS CUI [3,2])
C0332197 (UMLS CUI [4,1])
C0023418 (UMLS CUI [4,2])
C0544452 (UMLS CUI [4,3])
C1982687 (UMLS CUI [5,1])
C0439165 (UMLS CUI [5,2])
C0332437 (UMLS CUI [5,3])
C1982687 (UMLS CUI [6,1])
C0439165 (UMLS CUI [6,2])
C0016263 (UMLS CUI [6,3])
Shortening Fraction
Item
shortening fraction greater than or equal to 25%.
boolean
C1335957 (UMLS CUI [1])
Glomerular Filtration Rate
Item
glomerular filtration rate greater than or equal to 50 cc/min/1.73 m2.
boolean
C0017654 (UMLS CUI [1])
Oximetry, Pulse
Item
pulse oximetry greater than or equal to 92% on room air.
boolean
C0034108 (UMLS CUI [1])
Bilirubin, direct measurement
Item
direct bilirubin less than or equal to 3.0 mg/dl.
boolean
C0201916 (UMLS CUI [1])
Alanine aminotransferase measurement
Item
alanine aminotransferase (alt) is no more than 2 times the upper limit of normal.
boolean
C0201836 (UMLS CUI [1])
Aspartate aminotransferase measurement
Item
aspartate transaminases (ast) is no more than 2 times the upper limit of normal.
boolean
C0201899 (UMLS CUI [1])
Karnofsky Performance Status | Lansky Play-Performance Status
Item
karnofsky or lansky performance score of greater than or equal to 50.
boolean
C0206065 (UMLS CUI [1])
C1522275 (UMLS CUI [2])
Absence Hypersensitivity Product Murine | HAMA test Normal
Item
no known allergy to murine products or hama testing results within normal limits.
boolean
C0332197 (UMLS CUI [1,1])
C0020517 (UMLS CUI [1,2])
C1254351 (UMLS CUI [1,3])
C0026809 (UMLS CUI [1,4])
C1868744 (UMLS CUI [2,1])
C0205307 (UMLS CUI [2,2])
Gene Transfer Agent Absent | Retroviral vector Absent | Adenoviral Vector Absent | Other Coding
Item
no prior receipt of a gene-transfer agent (e.g. retroviral, adenoviral, lentiviral vector).
boolean
C1880946 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1514926 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C1510800 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C3846158 (UMLS CUI [4])
Pleural effusion Absent | Pericardial effusion Absent
Item
does not have a current pleural or pericardial effusion.
boolean
C0032227 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0031039 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Donor Family member Adult Available | Donor Suitable Natural Killer Cells Transplantation
Item
has a suitable adult family member donor available for nk cell donation.
boolean
C0013018 (UMLS CUI [1,1])
C0086282 (UMLS CUI [1,2])
C0001675 (UMLS CUI [1,3])
C0470187 (UMLS CUI [1,4])
C0013018 (UMLS CUI [2,1])
C3900053 (UMLS CUI [2,2])
C0022688 (UMLS CUI [2,3])
C0040732 (UMLS CUI [2,4])
Toxicity CTCAE Grades | Etiology Prior Therapy | Patient recovered
Item
has recovered from all acute nci common toxicity criteria grade ii-iv non-hematologic acute toxicities resulting from previous therapy as per the judgment of the principal investigator.
boolean
C0600688 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
C0015127 (UMLS CUI [2,1])
C1514463 (UMLS CUI [2,2])
C1115804 (UMLS CUI [3])
Biological treatment | Systemic Chemotherapy | Therapeutic radiology procedure
Item
at least two weeks since receipt of any biological therapy, systemic chemotherapy, and/or radiation therapy.
boolean
C1531518 (UMLS CUI [1])
C1883256 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
Prednisone Equivalent U/day
Item
is not receiving more than the equivalent of prednisone 10 mg daily.
boolean
C0032952 (UMLS CUI [1,1])
C0205163 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
Pregnancy | Serum pregnancy test negative Required | Urine pregnancy test negative Required
Item
pregnant (negative serum or urine pregnancy test to be conducted within 7 days prior to enrollment)
boolean
C0032961 (UMLS CUI [1])
C0430061 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0430057 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
Breast Feeding
Item
breastfeeding
boolean
C0006147 (UMLS CUI [1])