ID

30286

Description

Impact of Endostar Combined With Chemotherapy on the Angiogenesis of Advanced Non-small Cell Lung Cancer (NSCLC); ODM derived from: https://clinicaltrials.gov/show/NCT00657423

Link

https://clinicaltrials.gov/show/NCT00657423

Keywords

  1. 5/27/18 5/27/18 -
Copyright Holder

See clinicaltrials.gov

Uploaded on

May 27, 2018

DOI

To request one please log in.

License

Creative Commons BY 4.0

Model comments :

You can comment on the data model here. Via the speech bubbles at the itemgroups and items you can add comments to those specificially.

Itemgroup comments for :

Item comments for :

In order to download data models you must be logged in. Please log in or register for free.

Eligibility Lung Neoplasms NCT00657423

Eligibility Lung Neoplasms NCT00657423

Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
clinical diagnosis of advanced or metastatic nsclc (confirmed histologically, with a tumor that was measurable by clinical and/or radiologic examination.
Description

Non-Small Cell Lung Carcinoma Advanced | Non-small cell lung cancer metastatic | Measurable Disease Clinical examination | Measurable Disease Radiologic examination

Data type

boolean

Alias
UMLS CUI [1,1]
C0007131
UMLS CUI [1,2]
C0205179
UMLS CUI [2]
C0278987
UMLS CUI [3,1]
C1513041
UMLS CUI [3,2]
C1456356
UMLS CUI [4,1]
C1513041
UMLS CUI [4,2]
C0043299
have an eastern cooperative oncology group performance status 0 to 2.
Description

ECOG performance status

Data type

boolean

Alias
UMLS CUI [1]
C1520224
adequate renal, cardiac, hepatic, and hematologic function as indicated by the following parameters: absolute neutrophil count 2 x the ninth power of ten/l, thrombocytes 100 x the ninth power of ten/l, hemoglobin 10 g/dl, total bilirubin 1.25x the upper limit of normal range (uln), alt and ast 1.5x uln, alkaline phosphatase 5x uln, creatinine 1.15x uln.
Description

Renal function | Cardiac function | Liver function | Hematologic function | Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement | Elevated total bilirubin | Alanine aminotransferase increased | Aspartate aminotransferase increased | Alkaline phosphatase raised | Serum creatinine raised

Data type

boolean

Alias
UMLS CUI [1]
C0232804
UMLS CUI [2]
C0232164
UMLS CUI [3]
C0232741
UMLS CUI [4]
C0221130
UMLS CUI [5]
C0948762
UMLS CUI [6]
C0032181
UMLS CUI [7]
C0518015
UMLS CUI [8]
C0741494
UMLS CUI [9]
C0151905
UMLS CUI [10]
C0151904
UMLS CUI [11]
C0151849
UMLS CUI [12]
C0700225
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
known brain metastases or secondary neoplasia.
Description

Metastatic malignant neoplasm to brain | Neoplasia Secondary

Data type

boolean

Alias
UMLS CUI [1]
C0220650
UMLS CUI [2,1]
C1882062
UMLS CUI [2,2]
C0175668
myocardial insufficiency or myocardial infarction within the preceding 6 months.
Description

Myocardial insufficiency | Myocardial Infarction

Data type

boolean

Alias
UMLS CUI [1]
C1401079
UMLS CUI [2]
C0027051
severe renal or hepatic insufficiency.
Description

Renal Insufficiency Severe | Hepatic Insufficiency Severe

Data type

boolean

Alias
UMLS CUI [1,1]
C1565489
UMLS CUI [1,2]
C0205082
UMLS CUI [2,1]
C1306571
UMLS CUI [2,2]
C0205082
pre-existing motor or sensor neurotoxicity who grade 2.
Description

Neurotoxicity Motor Pre-existing Grade | Neurotoxicity Sensory Pre-existing Grade | WHO classification

Data type

boolean

Alias
UMLS CUI [1,1]
C0235032
UMLS CUI [1,2]
C0501384
UMLS CUI [1,3]
C2347662
UMLS CUI [1,4]
C0441800
UMLS CUI [2,1]
C0235032
UMLS CUI [2,2]
C0445254
UMLS CUI [2,3]
C2347662
UMLS CUI [2,4]
C0441800
UMLS CUI [3]
C4267671
severe psychologic disease.
Description

Mental Disorder, Severe

Data type

boolean

Alias
UMLS CUI [1]
C4046029
active infection, or other condition that could compromise protocol compliance.
Description

Communicable Disease compromises Protocol Compliance | Condition compromises Protocol Compliance

Data type

boolean

Alias
UMLS CUI [1,1]
C0009450
UMLS CUI [1,2]
C2945640
UMLS CUI [1,3]
C0525058
UMLS CUI [2,1]
C0348080
UMLS CUI [2,2]
C2945640
UMLS CUI [2,3]
C0525058
simultaneous administration of other antineoplastic medications.
Description

Antineoplastic Agents

Data type

boolean

Alias
UMLS CUI [1]
C0003392
clinically significant hemoptysis.
Description

Hemoptysis Clinical Significance

Data type

boolean

Alias
UMLS CUI [1,1]
C0019079
UMLS CUI [1,2]
C2826293
pregnancy and/or lactation.
Description

Pregnancy | Breast Feeding

Data type

boolean

Alias
UMLS CUI [1]
C0032961
UMLS CUI [2]
C0006147

Similar models

Eligibility Lung Neoplasms NCT00657423

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
Non-Small Cell Lung Carcinoma Advanced | Non-small cell lung cancer metastatic | Measurable Disease Clinical examination | Measurable Disease Radiologic examination
Item
clinical diagnosis of advanced or metastatic nsclc (confirmed histologically, with a tumor that was measurable by clinical and/or radiologic examination.
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0278987 (UMLS CUI [2])
C1513041 (UMLS CUI [3,1])
C1456356 (UMLS CUI [3,2])
C1513041 (UMLS CUI [4,1])
C0043299 (UMLS CUI [4,2])
ECOG performance status
Item
have an eastern cooperative oncology group performance status 0 to 2.
boolean
C1520224 (UMLS CUI [1])
Renal function | Cardiac function | Liver function | Hematologic function | Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement | Elevated total bilirubin | Alanine aminotransferase increased | Aspartate aminotransferase increased | Alkaline phosphatase raised | Serum creatinine raised
Item
adequate renal, cardiac, hepatic, and hematologic function as indicated by the following parameters: absolute neutrophil count 2 x the ninth power of ten/l, thrombocytes 100 x the ninth power of ten/l, hemoglobin 10 g/dl, total bilirubin 1.25x the upper limit of normal range (uln), alt and ast 1.5x uln, alkaline phosphatase 5x uln, creatinine 1.15x uln.
boolean
C0232804 (UMLS CUI [1])
C0232164 (UMLS CUI [2])
C0232741 (UMLS CUI [3])
C0221130 (UMLS CUI [4])
C0948762 (UMLS CUI [5])
C0032181 (UMLS CUI [6])
C0518015 (UMLS CUI [7])
C0741494 (UMLS CUI [8])
C0151905 (UMLS CUI [9])
C0151904 (UMLS CUI [10])
C0151849 (UMLS CUI [11])
C0700225 (UMLS CUI [12])
Item Group
C0680251 (UMLS CUI)
Metastatic malignant neoplasm to brain | Neoplasia Secondary
Item
known brain metastases or secondary neoplasia.
boolean
C0220650 (UMLS CUI [1])
C1882062 (UMLS CUI [2,1])
C0175668 (UMLS CUI [2,2])
Myocardial insufficiency | Myocardial Infarction
Item
myocardial insufficiency or myocardial infarction within the preceding 6 months.
boolean
C1401079 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
Renal Insufficiency Severe | Hepatic Insufficiency Severe
Item
severe renal or hepatic insufficiency.
boolean
C1565489 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1306571 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Neurotoxicity Motor Pre-existing Grade | Neurotoxicity Sensory Pre-existing Grade | WHO classification
Item
pre-existing motor or sensor neurotoxicity who grade 2.
boolean
C0235032 (UMLS CUI [1,1])
C0501384 (UMLS CUI [1,2])
C2347662 (UMLS CUI [1,3])
C0441800 (UMLS CUI [1,4])
C0235032 (UMLS CUI [2,1])
C0445254 (UMLS CUI [2,2])
C2347662 (UMLS CUI [2,3])
C0441800 (UMLS CUI [2,4])
C4267671 (UMLS CUI [3])
Mental Disorder, Severe
Item
severe psychologic disease.
boolean
C4046029 (UMLS CUI [1])
Communicable Disease compromises Protocol Compliance | Condition compromises Protocol Compliance
Item
active infection, or other condition that could compromise protocol compliance.
boolean
C0009450 (UMLS CUI [1,1])
C2945640 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C0348080 (UMLS CUI [2,1])
C2945640 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
Antineoplastic Agents
Item
simultaneous administration of other antineoplastic medications.
boolean
C0003392 (UMLS CUI [1])
Hemoptysis Clinical Significance
Item
clinically significant hemoptysis.
boolean
C0019079 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
Pregnancy | Breast Feeding
Item
pregnancy and/or lactation.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])

Please use this form for feedback, questions and suggestions for improvements.

Fields marked with * are required.

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial