Study Subject Newly Diagnosed
Item
newly diagnosed subjects
boolean
C0681850 (UMLS CUI [1,1])
C1518321 (UMLS CUI [1,2])
Age
Item
the subject is male or female, aged 18 years of age or older
boolean
C0001779 (UMLS CUI [1])
Acute lymphocytic leukemia | Leukemia, Myelocytic, Acute
Item
the subject has a diagnosis of acute lymphocytic leukemia (all) or acute myelogenous leukemia (aml); the subject must have a pathology-confirmed diagnosis
boolean
C0023449 (UMLS CUI [1])
C0023467 (UMLS CUI [2])
Diagnosis Pathology Confirmed
Item
the subject must have a pathology-confirmed diagnosis
boolean
C0011900 (UMLS CUI [1,1])
C0919386 (UMLS CUI [1,2])
C0521093 (UMLS CUI [1,3])
Acute lymphocytic leukemia | Leukemia, Myelocytic, Acute | Blasts Bone marrow Percentage | Blast Cell Percentage Peripheral blood
Item
acute lymphocytic leukemia (all) or acute myelogenous leukemia (aml) is defined as having >25% blasts in the bone marrow and/or peripheral blood
boolean
C0023449 (UMLS CUI [1])
C0023467 (UMLS CUI [2])
C1982687 (UMLS CUI [3,1])
C0439165 (UMLS CUI [3,2])
C0368761 (UMLS CUI [4,1])
C0439165 (UMLS CUI [4,2])
C0229664 (UMLS CUI [4,3])
Absence Chemotherapy Acute leukemia | Absence Therapeutic procedure Acute leukemia
Item
the subject has not received any chemotherapy or treatment for their acute leukemia prior to the initial study visit
boolean
C0332197 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0085669 (UMLS CUI [1,3])
C0332197 (UMLS CUI [2,1])
C0087111 (UMLS CUI [2,2])
C0085669 (UMLS CUI [2,3])
Informed Consent
Item
the subject is able and willing to provide written informed consent
boolean
C0021430 (UMLS CUI [1])
Comprehension Study Protocol | Protocol Compliance
Item
the subject is able to understand the study and cooperate with all study instructions
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2])
Recurrent disease
Item
relapsed subjects
boolean
C0277556 (UMLS CUI [1])
Age
Item
the subject is male or female, aged 18 years of age or older
boolean
C0001779 (UMLS CUI [1])
ALL in relapse | AML in relapse
Item
the subject has a diagnosis of relapsed acute lymphocytic leukemia (all) or relapsed acute myelogenous leukemia (aml)
boolean
C2367454 (UMLS CUI [1])
C2367456 (UMLS CUI [2])
Diagnosis Pathology Confirmed
Item
the subject must have a pathology-confirmed diagnosis
boolean
C0011900 (UMLS CUI [1,1])
C0919386 (UMLS CUI [1,2])
C0521093 (UMLS CUI [1,3])
Acute lymphocytic leukemia | Leukemia, Myelocytic, Acute | Blasts Bone marrow Percentage | Blast Cell Percentage Peripheral blood
Item
acute lymphocytic leukemia (all) or acute myelogenous leukemia (aml) is defined as having ≥ 25% blasts in the bone marrow and/or peripheral blood
boolean
C0023449 (UMLS CUI [1])
C0023467 (UMLS CUI [2])
C1982687 (UMLS CUI [3,1])
C0439165 (UMLS CUI [3,2])
C0368761 (UMLS CUI [4,1])
C0439165 (UMLS CUI [4,2])
C0229664 (UMLS CUI [4,3])
Chemotherapeutic agent Quantity Acute leukemia
Item
the subject has received one or more of the pre-identified chemotherapeutic agents for treatment of their initial acute leukemia diagnosis
boolean
C0729502 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0085669 (UMLS CUI [1,3])
Absence Systemic Chemotherapy Acute leukemia in relapse | Absence Systemic therapy Acute leukemia in relapse
Item
the subject has not received any systemic chemotherapy or treatment for their relapsed acute leukemia
boolean
C0332197 (UMLS CUI [1,1])
C1883256 (UMLS CUI [1,2])
C2367453 (UMLS CUI [1,3])
C0332197 (UMLS CUI [2,1])
C1515119 (UMLS CUI [2,2])
C2367453 (UMLS CUI [2,3])
Intrathecal chemotherapy
Item
receipt of intrathecal chemotherapy will be permissible
boolean
C1517560 (UMLS CUI [1])
Informed Consent
Item
the subject is able and willing to provide written informed consent
boolean
C0021430 (UMLS CUI [1])
Comprehension Study Protocol | Protocol Compliance
Item
the subject is able to understand the study and cooperate with all study instructions
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2])
Disease Serious Uncontrolled | Serious mental illness Uncontrolled | At risk Patient safety | At risk Patient Data Collection
Item
the subject has an uncontrolled serious medical or psychiatric illness that, in the opinion of the investigator, would compromise the subject's safety or collection of data
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0205318 (UMLS CUI [1,3])
C3841614 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C1444641 (UMLS CUI [3,1])
C1113679 (UMLS CUI [3,2])
C1444641 (UMLS CUI [4,1])
C0030705 (UMLS CUI [4,2])
C0010995 (UMLS CUI [4,3])
Investigational New Drugs
Item
the subject received treatment with an investigational drug within two weeks of the initial or subsequent study visits
boolean
C0013230 (UMLS CUI [1])
Age
Item
subjects under the age of 18
boolean
C0001779 (UMLS CUI [1])