Acute Myelocytic Leukemia de novo | Secondary acute myeloid leukemia
Item
diagnosis of de novo or secondary acute myeloid leukemia meeting the following criterion:
boolean
C0023467 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C0280449 (UMLS CUI [2])
Recurrent disease Post Complete remission
Item
relapse > 1 year after obtaining complete remission (any prior treatment allowed)
boolean
C0277556 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C0677874 (UMLS CUI [1,3])
Disease Philadelphia chromosome positive Blast Phase
Item
philadelphia chromosome-positive disease in blast crisis
boolean
C0012634 (UMLS CUI [1,1])
C0856536 (UMLS CUI [1,2])
C0005699 (UMLS CUI [1,3])
Disease French-American-British Classification
Item
fab m3, m6, or m7 disease
boolean
C0012634 (UMLS CUI [1,1])
C2984084 (UMLS CUI [1,2])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Life Expectancy
Item
life expectancy ≥ 4 weeks
boolean
C0023671 (UMLS CUI [1])
Transaminase Assay
Item
transaminases ≤ 5 times normal
boolean
C0919834 (UMLS CUI [1])
Creatinine measurement, serum
Item
creatinine ≤ 2 times normal
boolean
C0201976 (UMLS CUI [1])
Serum total bilirubin measurement | Exception Involvement Visceral
Item
bilirubin ≤ 3 times normal (except if visceral involvement present)
boolean
C1278039 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1314939 (UMLS CUI [2,2])
C0442045 (UMLS CUI [2,3])
Alkaline phosphatase measurement | Gamma glutamyl transferase measurement
Item
alkaline phosphatase or gamma-glutamyltransferase ≤ 5 times normal
boolean
C0201850 (UMLS CUI [1])
C0202035 (UMLS CUI [2])
Pregnancy Absent | Breast Feeding Absent
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Pregnancy test negative
Item
negative pregnancy test
boolean
C0427780 (UMLS CUI [1])
Fertility Contraceptive methods
Item
fertile patients of must use effective contraception during and for ≥ 28 days after completion of study therapy
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
FEV1
Item
fev1 < 30%
boolean
C0849974 (UMLS CUI [1])
Infectious disease of lung Uncontrolled | Infectious disease of lung Viral
Item
active uncontrolled or viral pulmonary infection
boolean
C0876973 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0876973 (UMLS CUI [2,1])
C0521026 (UMLS CUI [2,2])
Serious mental illness Independent of Leukemia | Condition Preventing Comprehension Study Protocol
Item
serious psychiatric disorders not related to leukemia or any condition that would prohibit comprehension of the study
boolean
C3841614 (UMLS CUI [1,1])
C0332291 (UMLS CUI [1,2])
C0023418 (UMLS CUI [1,3])
C0348080 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C0162340 (UMLS CUI [2,3])
C2348563 (UMLS CUI [2,4])
HIV Seropositivity
Item
hiv-positive
boolean
C0019699 (UMLS CUI [1])
Cancer Other | Exception Skin carcinoma Noninvasive | Exception Carcinoma in Situ
Item
other concurrent malignancy except noninvasive skin cancer or carcinoma in situ
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])
C2986496 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0007099 (UMLS CUI [3,2])
Patients In prison | Patient supervision | Guardianship
Item
patients who are incarcerated or under supervision or trusteeship
boolean
C0030705 (UMLS CUI [1,1])
C0392751 (UMLS CUI [1,2])
C0814286 (UMLS CUI [2])
C0870627 (UMLS CUI [3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
ID.21
Item
see disease characteristics
boolean
Investigational New Drugs
Item
prior experimental medication within the past 4 weeks
boolean
C0013230 (UMLS CUI [1])